The psychosocial and financial impact of non-severe hypoglycemic events on people with diabetes: two international surveys

Abstract

The findings suggest that nocturnal and daytime non-severe hypoglycemic events have a large financial and psychosocial impact. Diabetes management that minimizes hypoglycemia while maintaining good glycemic control may positively impact upon the psychological wellbeing of people with diabetes, as well as reducing healthcare costs and increasing work productivity.

Assessing the impact of non-severe hypoglycemic events and treatment in adults: development of the Treatment-Related Impact Measure—Non-severe Hypoglycemic Events (TRIM-HYPO)

“…Further, since each domain of the TRIM-HYPO has been validated as well as the total score, the The concept elicitation phase of the TRIM-HYPO development clearly confirmed not only the broad spectrum of domains that are impacted by these events, but also that the severity of these impacts can be very detrimental to patients' daily functioning and well-being. These findings confirm findings from prior studies that have reported major and life disruptive impacts of non-severe hypoglycemic events [35,36]. Further, the validation phase of the TRIM-HYPO development found that the measure can be considered well validated as the PCA confirmed the preliminary theoretical framework, the item-to-domain correlations, and the overall fit statistics showed high item reliability coefficients, indicating that each of the TRIM-HYPO domains is a reliable measure with a good spread placement of items along the scale.…”

Continuous Glucose Monitoring: A Review of Recent Studies Demonstrating Improved Glycemic Outcomes

“…Brod [130][131][132] and coworkers have reported a series of studies showing the enormous economic, psychological, and loss-of-work-productivity costs of nonsevere hypoglycemia. This factor must also be considered when evaluating the cost-effectiveness of approaches to mitigate hypoglycemia.…”

Cost-effectiveness of Continuous Glucose Monitoring for Adults With Type 1 Diabetes Compared With Self-Monitoring of Blood Glucose: The DIAMOND Randomized Trial

“…The cost of a NSHE episode used in the study was $20.32, including $11.09 in direct medical costs and $9.23 in indirect costs (35,36). Lowering NSHEs not only reduces the risk of subsequent severe hypoglycemia (37) but also improves QoL, including psychological well-being, adherence to treatment regimens, work productivity, and quality and quantity of sleep (6,18,19).…”

“…, which greatly increase the costs of diabetes care (1,5). A barrier to delivering intensive glycemic management is the increased risk of hypoglycemia (severe and nonsevere), which negatively affects quality of life (QoL) and further increases treatment costs (6,7).…”