The psychology of Tourette disorder: Revisiting the past and moving toward a cognitively-oriented future

Gagné, Jean-Philippe

doi:10.1016/j.cpr.2018.09.005

Cited by 23 publications

(14 citation statements)

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“…Por otra parte, dentro del tratamiento, se encuentra el ámbito psicológico, lo cual incluye la Intervención conductual integral (ICI) y la terapia de aceptación y de compromiso. El estándar de oro del tratamiento es la ICI la cual busca que el paciente con ST esté al tanto de las urgencias premonitorias de los tics y este pueda actuar de cierta manera respondiendo de una manera adecuada 7,8 .…”

Section: Síndrome De Touretteunclassified

“…La depresión y la ansiedad juegan un papel muy importante en las personas con ST debido a que, como mencionan diferentes estudios, estas comorbilidades se consideran factores de riesgo para el aumento de la sintomatología, es decir, el inicio y la exageración de los movimientos involuntarios, siendo la mayoría de las veces el factor mas importante por el cual la persona se rehúsa a realizar las actividades cotidianas de la vida e incluso a realizar actividades recreativas públicas en las cuales puedan ser juzgados por la ignorancia de la gente hacia la enfermedad 8 .…”

Section: Síndrome De Tourette Y Comorbilidadesunclassified

“…Estas creencias negativas sobre los tics generan incomodidad. Es por esto que las personas con ST erróneamente creen que el sentir incomodidad se traduce como una situación catastrófica, intolerable y de larga duración y que vivir con esta incomodidad es muy difícil 8 . En la escena de la película, donde Brad es llevado de nueva cuenta con el director por interrumpir con sus tics la clase de matemáticas, este lo invita a asistir a una presentación de la orquesta escolar, a lo que Brad responde que no, ya que no quiere causar "problemas".…”

Section: Socialización En Los Pacientes Con Síndrome De Touretteunclassified

“…En la película Brad no recibe terapia, sin embargo, con ayuda de su madrastra, luego de su última entrevista que resultó ser un desastre, ésta le dice que no es su enfermedad la que lo detiene, sino es él quien se está frenando. Brad ante esto se da cuenta que debe coexistir con sus tics y aceptarlos como son y demostrar que no son un impedimento para que pueda ejercer como profesor 7,8 .…”

Section: Socialización En Los Pacientes Con Síndrome De Touretteunclassified

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El primero de la clase (2008): un reto de aceptación social

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Rubio

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Recibido el 22 de octubre de 2018; aceptado el 4 de diciembre de 2018. RMCOriginal JMM Los autores declaran que el artículo es original y que no ha sido publicado previamente. 95 Rev Med Cine 2019; 15(2): 95-100 Ediciones Universidad de Salamanca / CC BY NC ND J Med Mov 2019; 15(2): 95-100 ResumenLa película El primero de la clase (2008) de Peter Werner, se encuentra basada en la vida de Brad Cohen, quien a partir de los 6 años empiezó a presentar manifestaciones clínicas del síndrome de Tourette. La trama se desarrolla entorno a como Brad vive su día a día con su enfermedad y cómo este logra enfrentar los diversos obstáculos que la sociedad le presenta para lograr su más grande sueño: ser profesor de escuela primaria. Brad es continuamente burlado por parte de sus compañeros, convive con profesores intolerantes e incluso tiene un padre muy poco comprensivo, esto debido a que se desconocía que era un portador de Síndrome de Tourette (ST), lo cual generó que en un principio se aislara de los demás y no quisiera interactuar con otras personas. Durante el filme observamos como continuamente Brad es víctima del estigma social al no poder comportarse como los demás a causa del ST, impidiéndole en un principio tener amigos y posteriormente conseguir trabajo. En el presente artículo, ofreceremos una revisión del padecimiento, para comprender sus manifestaciones y el modo en el que afectaron la vida de Brad.Palabras clave: síndrome de Tourette, signos y síntomas, enfermedad del sistema nervioso. SummaryThe film Front of the class (2008) by Peter Werner, is based on the life of Brad Cohen, from the age of 6 presented clinical manifestations of Tourette syndrome. The plot describes how Brad lived his day to day with his illness and how he managed with the various obstacles that society presented to achieve his greatest dream: to be an elementary school teacher. Brad was continuously bullied by his peers, he had intolerant teachers and even a very unsympathetic father, perhaps because his father did not know that he was a carrier of Tourette syndrome (TS), a disease that involves social isolation from the others and aversion to interact with other people. During the film we observe how Brad is a victim of social stigma by not being able to behave like this peers because of the TS, preventing him in the beginning to have friends and then and then, to get a job. In this article, we will offer a review of the Tourette´s Syndrome to understand its manifestations and the way in which Brad's life was affected. Front of the Class (2008): A challenge of Social AcceptanceCómo citar este artículo: Novelo Alcocer V, Janssen Aguilar R, Lizama Rubio MA, Méndez Domínguez NI. El primero de la clase (2008): un reto de aceptación social. Rev Med Cine [Internet] 2019;15(2): 95-100. Color: color. Duración: 95 minutos. Género: drama, discapacidad, educación, enfermedad, película de televisión. Sinopsis: "Siendo retado desde muy joven por el síndrome de Tourette, Brad Cohen desafía todas las posibilidades para convertirse en un maestro talentos...

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Section: Síndrome De Touretteunclassified

Section: Síndrome De Tourette Y Comorbilidadesunclassified

Section: Socialización En Los Pacientes Con Síndrome De Touretteunclassified

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El primero de la clase (2008): un reto de aceptación social

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et al. 2019

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“…In addition, studies have also shown that TS is more common in males than females, the ratio between male and female is about 3-4:1 [4,8]. Although the etiology and pathogenesis of TS remain uncertain, it has been proved to be closely related to genetic factors, neurobiochemical factors, environmental factors, psychology, and other factors [10][11][12][13]. Besides, Evidence has shown that the Cortico Striato Thalamo Cortex (CSTC) loop is related to the pathophysiology of TS closely [14].…”

Section: Introductionmentioning

confidence: 99%

Potential Plasma Metabolic Biomarkers of Tourette Syndrome Discovery Based on Integrated Non-Targeted and Targeted Metabolomics Screening

Zhou

Huan

et al. 2020

Preprint

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Background Tourette syndrome (TS) is a chronic neuropsychiatric disorder, characterized by abnormal movements and phonations, tics, but accurate TS diagnosis remains challenging and indeed depends on its description of clinical symptoms. Our study was to identify some metabolites biomarkers based on non-targeted and targeted metabolomics. Methods We conducted untargeted ultra-high-performance liquid chromatography -quadrupole time-off light mass spectrometry (UHPLC-Q-TOF/MS) for preliminary screening of potential biomarkers from 30 TS patients and 10 healthy controls. And then performed validation experiments based on targeted ultra-high-performance liquid Chromatography-Triple Quadrupole-MS (UHPLC/MS/MS).Results 1775 differentially metabolites were identified by partial least squares discriminant analysis (PLS-DA), fold change analysis, T-tests, and hierarchical clustering analysis (Adjusted p-value < 0.05 and |logFC| >1). TS plasma samples were found differentiated from healthy samples in our approach. Further, the aspartate and asparagine metabolism pathway was considered as a significant enrichment pathway in TS progression based on the metabolite pathway enrichment analysis. For the 8 metabolites involved in this pathway that we detected, we then performed validation experiments based on targeted UHPLC/MS/MS from 35 TS patients and 14 healthy controls. T-test, Mann-Whitney U test, and receiver operating characteristic (ROC) curve analysis were used to determine potential biomarkers. Ultimately, L-Arginine and L-Pipecolic acid were validated as significantly differentiated metabolites (p<0.05) with an AUC of 70% and 87%.Conclusions L-Arginine and L-Pipecolic acid were defined as potential biomarkers for TS diagnosis by the combined application of non-targeted and targeted metabolomics analysis.

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European clinical guidelines for Tourette syndrome and other tic disorders—version 2.0. Part II: psychological interventions

Andrén

Jakubovski

Murphy

et al. 2021

Eur Child Adolesc Psychiatry

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Part II of the European clinical guidelines for Tourette syndrome and other tic disorders (ECAP journal, 2011) provides updated information and recommendations for psychological interventions for individuals with tic disorders, created by a working group of the European Society for the Study of Tourette Syndrome (ESSTS). A systematic literature search was conducted to obtain original studies of psychological interventions for tic disorders, published since the initial European clinical guidelines were issued. Relevant studies were identified using computerized searches of the MEDLINE and PsycINFO databases for the years 2011–2019 and a manual search for the years 2019–2021. Based on clinical consensus, psychoeducation is recommended as an initial intervention regardless of symptom severity. According to a systematic literature search, most evidence was found for Habit Reversal Training (HRT), primarily the expanded package Comprehensive Behavioral Intervention for Tics (CBIT). Evidence was also found for Exposure and Response Prevention (ERP), but to a lesser degree of certainty than HRT/CBIT due to fewer studies. Currently, cognitive interventions and third-wave interventions are not recommended as stand-alone treatments for tic disorders. Several novel treatment delivery formats are currently being evaluated, of which videoconference delivery of HRT/CBIT has the most evidence to date. To summarize, when psychoeducation alone is insufficient, both HRT/CBIT and ERP are recommended as first-line interventions for tic disorders. As part of the development of the clinical guidelines, a survey is reported from ESSTS members and other tic disorder experts on preference, use and availability of psychological interventions for tic disorders.

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The psychology of Tourette disorder: Revisiting the past and moving toward a cognitively-oriented future

Cited by 23 publications

References 116 publications

El primero de la clase (2008): un reto de aceptación social

El primero de la clase (2008): un reto de aceptación social

Potential Plasma Metabolic Biomarkers of Tourette Syndrome Discovery Based on Integrated Non-Targeted and Targeted Metabolomics Screening

European clinical guidelines for Tourette syndrome and other tic disorders—version 2.0. Part II: psychological interventions

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