2007
DOI: 10.1016/j.jocn.2006.05.001
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The prothrombin gene G20210A variant and puerperal cerebral venous and sinus thrombosis in South Indian women

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Cited by 12 publications
(18 citation statements)
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References 28 publications
(27 reference statements)
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“…2 However, this mutation is not a risk factor for Tunisian patients with CVT in our study, which it is in agreement with data from India. 5 Also, our results agree with a Lebanese study. 4 This mutation seems to occur at lower frequencies than FVL in Lebanon and Tunisia.…”
Section: Discussionsupporting
confidence: 91%
“…2 However, this mutation is not a risk factor for Tunisian patients with CVT in our study, which it is in agreement with data from India. 5 Also, our results agree with a Lebanese study. 4 This mutation seems to occur at lower frequencies than FVL in Lebanon and Tunisia.…”
Section: Discussionsupporting
confidence: 91%
“…Several studies have found that the hyperhomocysteinemia is associated with a several fold-increased risk of CVT [13][14][15]. In the case of our patient, the elevated homocysteine levels were brought down by treatment with pyridoxine, methylcobalamin and folic acid supplementation, similarly described in another case by Hassan et al [16].…”
Section: Discussionsupporting
confidence: 78%
“…12 In another study, prothrombin gene G20210A was not found in any patient, whereas MTHFR C677T was present in 16.3% and factor V Leiden (heterozygous) in 2.3%. 13 We have evaluated 60% of our patients for various prothrombotic conditions, and none had antithrombin-III and prothrombin gene mutations. Protein S deficiency was the most common and was present in 57.1%, followed by the MTHFR variant gene in 35%.…”
Section: Discussionmentioning
confidence: 99%