“…The active ingredients of saffron are able to exert antioxidant (Nikbakht‐Jam et al, ; Rahiman, Akaberi, Sahebkar, Emami, & Tayarani‐Najaran, ; Yaribeygi, Mohammadi, Rezaee, & Sahebkar, ), anti‐inflammatory (Yaribeygi, Mohammadi, Rezaee, et al, ), memory enhancer (Abe & Saito, ; Ghadrdoost et al, ), antitumor (Hoshyar & Mollaei, ; Moradzadeh, Sadeghnia, Tabarraei, & Sahebkar, ), antidepressant (Jam et al, ; Lopresti & Drummond, ; Shafiee, Arekhi, Omranzadeh, & Sahebkar, ), antiasthma (Javadi, Sahebkar, & Emami, ), cough suppressant (El‐Alfy, ), cardiovascular protection (Hatziagapiou & Lambrou, ; Sobhani, Nami, Emami, Sahebkar, & Javadi, ), neuroprotection (Wang et al, ), visual function improvement (Liou et al, ; Riazi et al, ) and sexual behavior potentiation effects (Malviya, Malviya, Jain, & Vyas, ; Sadoughi, ; Table ). This evidence implies that the active compounds of saffron can alter molecular mechanisms by affecting transcription factors, growth factors and diverse intracellular signaling pathways (Samarghandian, Azimi‐Nezhad, & Farkhondeh, ; Yang et al, ; Yaribeygi, Mohammadi, Rezaee, et al, ).…”