Abstract:Background: In clinical studies, the combination of methylprednisolone (MP) and cyclophosphamide (CTX) has great benefits for patients with pulmonary fibrosis (PF), but the mechanism of improving PF is not clear.Methods: PF rat models were induced by bleomycin and treated with MP or MP/CTX combination. Transmission electron microscope, hematoxylin and eosin (H&E) and Masson staining were used to measure the morphology of PF. ELISA kits were used to test inflammatory factor levels. MDA, SOD, GSH-PX levels w… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.