The protective effect of pregabalin and xanthenone on testicular ischemia/reperfusion injury in rats
Maha M. Abdel‐Fattah,
Ahmed Mamdouh Ahmed,
Rabeh Khairy Saleh
et al.
Abstract:BackgroundTorsion of the spermatic cord is a hazardous and common urologic issue. The current work evaluates the possible protective effect of pregabalin (PGB) and xanthenone (XAN) in testicular ischemia/reperfusion injury induced by testicular torsion/detorsion in rats.Materials and methodsSeven groups of adult male Wistar albino rats were allocated randomly into seven groups, namely, sham control, torsion/detorsion (T/D), PGB 50 mg/kg, PGB 100 mg/kg, XAN 1 mg/kg, XAN 2 mg/kg, and PGB 50 mg/kg plus XAN 1 mg/k… Show more
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