The protective effect of coenzyme Q10 and berberine on sperm parameters, with and without varicocelectomy in rats with surgically induced varicoceles

Najaran, Hamed; Rashtbari, Hamid; Mohammadi, Abouzar; Soleimanifar, Fatemeh; Izadpanah, Fatemeh; Kashani, Hamed Haddad; Bafrani, Hassan Hassani

doi:10.1007/s00580-018-2850-y

Cited by 7 publications

(5 citation statements)

References 44 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This study indicated decreased concentration, motility, and viability of sperm in rats with varicocele after 2 months and also reduction in the same parameters and the membrane integrity of sperm after 4 months compared to healthy rats (p < .05). Several studies have reported the same results as those of the present study and documented increased concentration, motility, viability (Hassani-Bafrani et al, 2019;Najaran et al, 2019), and membrane integrity of sperm in the varicocele disease (Vivas-Acevedo et al, 2014). The high levels of ROS, however, have a direct correlation with a decrease in spermatozoa count, motility, morphology, and membrane integrity (Agarwal et al, 2014).…”

Section: Discussionsupporting

confidence: 87%

Lycopene improves testicular damage and sperm quality in experimentally induced varicocele: Relationship with apoptosis, hypoxia, and hyperthermia

Babaei

Asadpour

Mansouri

et al. 2022

Food Science & Nutrition

View full text Add to dashboard Cite

Varicocele is defined as high pressure, stasis in the spermatic veins, and venous enlargement of the scrotal pampiniform plexus (Yetkin & Ozturk, 2018). The prevalence of varicocele disease is about 35% and 80% with primary and secondary infertility, respectively (Alsaikhan et al., 2016). The relationship between varicocele and infertility is unclear, but several articles have demonstrated that varicocele has

show abstract

Section: Discussionsupporting

confidence: 87%

Lycopene improves testicular damage and sperm quality in experimentally induced varicocele: Relationship with apoptosis, hypoxia, and hyperthermia

Babaei

Asadpour

Mansouri

et al. 2022

Food Science & Nutrition

View full text Add to dashboard Cite

show abstract

“…In addition, the rate of nosocomial infections may be increased due to phototherapy [16,17]. The use of alternative therapeutic methods offered by traditional medicine such as herbal remedies may be beneficial in the recovery of infants from hyperbilirubinemia [18–22].…”

Section: Introductionmentioning

confidence: 99%

Comparison of Purgative Manna Drop and Phototherapy with Phototherapy Treatment of Neonatal Jaundice: A Randomized Double-Blind Clinical Trial

Monsef

Eghbalian²,

Rahimi³

2019

Osong Public Health Res Perspect

View full text Add to dashboard Cite

Objectives Herbal remedies such as purgative manna are used to treat neonatal jaundice. In this study Bilineaster drop (purgative manna) and phototherapy, and phototherapy treatment alone were compared by assessing phototherapy duration and number of days in hospital. Methods There were 150 consecutive term neonates with jaundice, weighting from 2,500 g to 4,000 g enrolled in this randomized double blind clinical trial. The neonates were randomly assigned to intervention and control groups. The control patients received only phototherapy and the intervention group underwent phototherapy treatment and purgative manna drop (5 drops per kg of body weight, 3 times a day). Direct and total measurements of bilirubin concentration in the serum were measured and the reduction in concentration of bilirubin was calculated. Results There were 28% of patients whose hospital duration following phototherapy was 2 days, for Bilineaster and phototherapy treatment this was 49.3% of patients. At 48 hours and 72 hours the reduction in the concentration of total bilirubin in the serum was statistically significantly different across groups ( p < 0.05) but at 24 hours and 96 hours there were no significant differences between groups ( p > 0.05). The reduction in direct bilirubin concentration in the serum was significantly different between groups at 72 hours and 96 hours ( p > 0.001). Conclusion Purgative manna and phototherapy, can statistically significantly reduce total bilirubin concentration at 48 hours and 72 hours compared with phototherapy alone, and reduce the length of hospital stay for jaundiced neonates at 2 days compared with phototherapy treatment.

show abstract

“…Initially, the normalization of the dependent variables is investigated using Kolmogorov Smirnov test [18][19][20], then, if the data are normal, binary variations in each group are performed using paired t-test and comparison of the two groups is done using independent t-test [21][22][23][24][25][26][27].…”

Section: Discussionmentioning

confidence: 99%

Effect of intraoperative dexmedetomidine infusion during functional endoscopic sinus surgery: a prospective cohort study

et al. 2020

View full text Add to dashboard Cite

Background Dexmedetomidine, an α2 agonist, has well-known anesthetic and analgesic-sparing effects. We designed this study to evaluate the effect of intraoperative dexmedetomidine infusion on intra operative blood loss and postoperative pain in functional endoscopic sinus surgery. Methods This prospective cohort study included 90 patients planning to undergo endoscopic sinus surgery, who were randomly divided into three groups. 2 to 2.5 mg/kg of propofol was used in all groups to induce anesthesia. One group received dexmedetomidine 0.2 μg/kg per hour infusion whereas the other group received dexmedetomidine 0.5 μg/kg per hour infusion. The control group received normal saline infusion. Results The mean age of patients was 41.02 ± 11.93. 33 patients in the dexmedetomidine 0.2 μg/kg/h group, 30 patients in the dexmedetomidine 0.5 μg/kg/h group and 27 patients in the placebo group. The lowest amount of bleeding was related to the dexmedetomidine 0.5 μg/kg/h group. The volume of bleeding between the three groups was significantly different (p = 0.012). The satisfaction of the surgeon in the dexmedetomidine 0.5 μg/kg/h group was more than other groups. There was a significant relationship between the satisfaction of the surgeon and the treatment groups (p < 0.001). The lowest duration of surgery was related to the dexmedetomidine 0.2 μg/kg/h group. The most Trinitroglycerin (TNG) consumption was in the placebo group and the highest dose of labetalol was in the dexmedetomidine 0.5 μg/kg/h group. There was no significant difference in the TNG and labetalol consumption between three groups. The lowest consumption of morphine and pethidine in the dexmedetomidine 0.5 μg/kg/h group. Conclusions Infusion of dexmedetomidine 0.5 μg/kg/h decreased blood loss and consumption of morphine and pethidine in patients who underwent endoscopic sinus surgery.

show abstract

The protective effect of coenzyme Q10 and berberine on sperm parameters, with and without varicocelectomy in rats with surgically induced varicoceles

Cited by 7 publications

References 44 publications

Lycopene improves testicular damage and sperm quality in experimentally induced varicocele: Relationship with apoptosis, hypoxia, and hyperthermia

Lycopene improves testicular damage and sperm quality in experimentally induced varicocele: Relationship with apoptosis, hypoxia, and hyperthermia

Comparison of Purgative Manna Drop and Phototherapy with Phototherapy Treatment of Neonatal Jaundice: A Randomized Double-Blind Clinical Trial

Effect of intraoperative dexmedetomidine infusion during functional endoscopic sinus surgery: a prospective cohort study

Contact Info

Product

Resources

About