The prophylaxis of severe hemophilia A with inhibitors in children in the Republic of Belarus: a 12-year experience
E. V. Dmitriev,
L. I. Volkova,
О. V. Aleinikova
et al.
Abstract:The development of inhibitory antibodies against FVIII is the most serious complication associated with the use of FVIII concentrates in hemophilia A patients. There is a need for more research on measures that could reduce the risk of inhibitor formation in previously untreated patients (PUPs) with severe hemophilia A. The purpose of this study was to determine the effectiveness of the prevention of clotting inhibitor development in PUPs (or minimally treated patients) with severe hemophilia A by administerin… Show more
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