The promising rise of bioprinting in revolutionalizing medical science: Advances and possibilities

Jamee, Radia; Araf, Yusha; Naser, Iftekhar Bin; Promon, Salman Khan

doi:10.1016/j.reth.2021.05.006

Cited by 22 publications

(7 citation statements)

References 202 publications

(215 reference statements)

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“…The various potential uses of 3D bio-printing are causing it to grow quickly into a significant industry. Numerous studies have recently found the use of 3D bio-printing in biomedical applications to be intriguing, and numerous businesses around the world have helped to further the use of this technology use in medicine by funding research projects in their labs [ 60 , 144 , 169 , 194 ]. The capacity to produce the optional product in accordance with particular patient needs makes this technology extremely advantageous for biomedical applications and devices.…”

Section: Biomedical Applications Of 3d Bio-printingmentioning

confidence: 99%

Recent Developments in 3D Bio-Printing and Its Biomedical Applications

Assad

Assad²,

Kumar³

2023

Pharmaceutics

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The fast-developing field of 3D bio-printing has been extensively used to improve the usability and performance of scaffolds filled with cells. Over the last few decades, a variety of tissues and organs including skin, blood vessels, and hearts, etc., have all been produced in large quantities via 3D bio-printing. These tissues and organs are not only able to serve as building blocks for the ultimate goal of repair and regeneration, but they can also be utilized as in vitro models for pharmacokinetics, drug screening, and other purposes. To further 3D-printing uses in tissue engineering, research on novel, suitable biomaterials with quick cross-linking capabilities is a prerequisite. A wider variety of acceptable 3D-printed materials are still needed, as well as better printing resolution (particularly at the nanoscale range), speed, and biomaterial compatibility. The aim of this study is to provide expertise in the most prevalent and new biomaterials used in 3D bio-printing as well as an introduction to the associated approaches that are frequently considered by researchers. Furthermore, an effort has been made to convey the most pertinent implementations of 3D bio-printing processes, such as tissue regeneration, etc., by providing the most significant research together with a comprehensive list of material selection guidelines, constraints, and future prospects.

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Section: Biomedical Applications Of 3d Bio-printingmentioning

confidence: 99%

Recent Developments in 3D Bio-Printing and Its Biomedical Applications

Assad

Assad²,

Kumar³

2023

Pharmaceutics

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“…In situ bioprinting is a novel technology that merges with portable bioprinting, so it has some facilities to improve the disease and accelerate healing. 47 When compared to standard in vitro bioprinting, in situ bioprinting may be favored since de novo tissues are produced immediately on the predicted anatomical site in the real organism. 48 In situ bioprinting may be described as the direct printing of bioinks to build or repair living tissues or organs at a fault location in a clinical context.…”

Section: In Situ Bioprintingmentioning

confidence: 99%

Portable hand‐held bioprinters promote in situ tissue regeneration

Pazhouhnia

Beheshtizadeh

Namini

et al. 2022

Bioengineering & Transla Med

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Three‐dimensional bioprinting, as a novel technique of fabricating engineered tissues, is positively correlated with the ultimate goal of regenerative medicine, which is the restoration, reconstruction, and repair of lost and/or damaged tissue function. The progressive trend of this technology resulted in developing the portable hand‐held bioprinters, which could be used quite easily by surgeons and physicians. With the advent of portable hand‐held bioprinters, the obstacles and challenges of utilizing statistical bioprinters could be resolved. This review attempts to discuss the advantages and challenges of portable hand‐held bioprinters via in situ tissue regeneration. All the tissues that have been investigated by this approach were reviewed, including skin, cartilage, bone, dental, and skeletal muscle regeneration, while the tissues that could be regenerated via this approach are targeted in the authors' perspective. The design and applications of hand‐held bioprinters were discussed widely, and the marketed printers were introduced. It has been prospected that these facilities could ameliorate translating the regenerative medicine science from the bench to the bedside actively.

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“…Three-dimensional bioprinting was developed on the basis of 3D printing. Cells and scaffolds are generally made of polymers and extruded from a nozzle and cultured in 3D ( Elalouf, 2021 ; Jamee et al, 2021 ). Many organs, such as bone ( Arrigoni et al, 2017 ; Kim et al, 2021 ; Alcala-Orozco et al, 2022 ), lung ( Hu et al, 2021 ), and skin ( Gao et al, 2021c ), have already been generated by 3D bioprinting, showing plenty of potential in the future.…”

Section: Advanced Models For Ex Vivo Non Studiesmentioning

confidence: 99%

Lab-on-Chip Microsystems for Ex Vivo Network of Neurons Studies: A Review

Zhang

Rong

Bian

2022

Front. Bioeng. Biotechnol.

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Increasing population is suffering from neurological disorders nowadays, with no effective therapy available to treat them. Explicit knowledge of network of neurons (NoN) in the human brain is key to understanding the pathology of neurological diseases. Research in NoN developed slower than expected due to the complexity of the human brain and the ethical considerations for in vivo studies. However, advances in nanomaterials and micro-/nano-microfabrication have opened up the chances for a deeper understanding of NoN ex vivo, one step closer to in vivo studies. This review therefore summarizes the latest advances in lab-on-chip microsystems for ex vivo NoN studies by focusing on the advanced materials, techniques, and models for ex vivo NoN studies. The essential methods for constructing lab-on-chip models are microfluidics and microelectrode arrays. Through combination with functional biomaterials and biocompatible materials, the microfluidics and microelectrode arrays enable the development of various models for ex vivo NoN studies. This review also includes the state-of-the-art brain slide and organoid-on-chip models. The end of this review discusses the previous issues and future perspectives for NoN studies.

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The promising rise of bioprinting in revolutionalizing medical science: Advances and possibilities

Cited by 22 publications

References 202 publications

Recent Developments in 3D Bio-Printing and Its Biomedical Applications

Recent Developments in 3D Bio-Printing and Its Biomedical Applications

Portable hand‐held bioprinters promote in situ tissue regeneration

Lab-on-Chip Microsystems for Ex Vivo Network of Neurons Studies: A Review

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