The progressive trend of modeling and drug screening systems of breast cancer bone metastasis
Hanieh Kolahi Azar,
Maliheh Gharibshahian,
Mohammadreza Rostami
et al.
Abstract:Bone metastasis is considered as a considerable challenge for breast cancer patients. Various in vitro and in vivo models have been developed to examine this occurrence. In vitro models are employed to simulate the intricate tumor microenvironment, investigate the interplay between cells and their adjacent microenvironment, and evaluate the effectiveness of therapeutic interventions for tumors. The endeavor to replicate the latency period of bone metastasis in animal models has presented a challenge, primarily… Show more
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