2020
DOI: 10.1007/s00595-020-02007-5
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The prognostic value of the prognostic nutritional index and inflammation-based markers in obstructive colorectal cancer

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Cited by 28 publications
(19 citation statements)
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“…Previous studies have reported the prognostic values of hs-mGPS, hsCRP/ALB, and PNI in cancers, [14][15][16][17][18]27 which were derived from two indicators of hsCRP, LYM, and ALB. To maximize the prognostic performance of these [30][31][32] our study revealed the AUCs of 0.591, 0.604 and 0.656 for hs-mGPS, hsCRP/ALB and PNI, which implies the repeatability of our results. Therefore, it is reasonable to infer that the better prognostic performance of IINS (AUC: 0.689; C-index: 0.681) is also valid for OS.…”
Section: Discussionmentioning
confidence: 63%
“…Previous studies have reported the prognostic values of hs-mGPS, hsCRP/ALB, and PNI in cancers, [14][15][16][17][18]27 which were derived from two indicators of hsCRP, LYM, and ALB. To maximize the prognostic performance of these [30][31][32] our study revealed the AUCs of 0.591, 0.604 and 0.656 for hs-mGPS, hsCRP/ALB and PNI, which implies the repeatability of our results. Therefore, it is reasonable to infer that the better prognostic performance of IINS (AUC: 0.689; C-index: 0.681) is also valid for OS.…”
Section: Discussionmentioning
confidence: 63%
“…PNI is mainly used to evaluate the nutritional status of patients with gastrointestinal malignant tumors and is calculated based on serum albumin concentration and total lymphocyte count. There are many reports on the prognostic role of PNI in colorectal cancer [ 7 , 26 ], but its significance in the screening and diagnosis of colorectal cancer is rarely discussed. Our results show that its AUCROC is 0.733, indicating that PNI has a high diagnostic accuracy for colorectal cancer and is a good potential screening marker.…”
Section: Discussionmentioning
confidence: 99%
“…PNI, determined by the albumin level and lymphocyte count, is regarded as the reflection of the immuno-nutritious status. PNI was reported to be equally as important as rating TNM stage in the management of CRC patients ( 25 ). SII was investigated as a potent prognostic index in several types of malignant tumors, including CRC ( 26 , 27 ).…”
Section: Discussionmentioning
confidence: 99%