The prognostic value of serum troponin T in unstable angina

Cina, Viviane; Gök, Kasan; Kaptanoǧlu, Bünyamin

doi:10.1016/0167-5273(95)02532-4

Cited by 14 publications

(3 citation statements)

References 30 publications

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“…When stratified by gender, males had higher procedures compared to females in both types of MI ( Table 3). The CABG procedures revealed increasing trends from 9% in 1990 to 10% in 1996 and decreased to 9% in 2006 for QWMI while wave MI (Table 1) might be due to changes in the pathophysiology of atherosclerotic plaque with the increasing incidence of [25,26] and non-ruptured plaques (more commonly associated with diabetes and younger age group) and increased risk of 1 inhibitor and tissue factor in diabetics, obesity and hypertension), The changes in the diagnostic criteria with the redefinition of AMI using as a biomarker with good sensitivity and specificity leading to probable distinction of unstable angina, NQWMI and QWMI [31][32][33][34] The role of aspirin in reducing the size of infarction leading to increasing incidence of unstable angina, use of and increasing prevalence of in preventing the evolution of NQWMI to QWMI, use of statins in reducing the inflammation and cholesterol in reducing the incidence of CHD 39]. The increasing elderly population [40] in the united states and increasing prevalence of diabetes, hyperlipidemia and associated with other modifiable risk factors like hypertension, smoking, physical activity, poor dietary contribute to incidence of AMI.…”

Section: Discussionmentioning

confidence: 99%

Secular trends of hospitalization and in-hospital mortality rates of Q-wave and Non-Q-wave myocardial infarction in US: 1990-2006

Ponna¹,

Pothula

Upadrasta³

2016

Public Health Rev: Int J Public Health Res

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Background: Q-wave and non-Q-wave electrocardiogram (EKG/ECG) findings are proving to be significant prognostic factors for Acute myocardial infarction (AMI) as corroborated from previous studies has implications in patient care. Objective: To document secular changes in proportion of Q-wave myocardial infarction (QWMI) and NQWMI hospitalizations from 1990-2006 and its correlation with changes in demographics and co-morbidities like diabetes mellitus, hypertension and shock, cardiac interventions like PCI and CABG and to investigate change in risk of QWMI and NQWMI death rates from 1990 to 2006. Methods: Trend analysis of QWMI and NQWMI hospitalizations and in-hospital death rates from 1990-2006 of 1,22,841 patients aged ≥35 years admitted for AMI of National Hospital Discharge Survey populationbased sample. Trends of QWMI and NQWMI hospitalization and death rates, procedure rates and risk of death from QWMI and NQWMI were documented. Results: The hospitalization rate of QWMI patients decreased from 56 for 100 AMI in 1990 and 92 to 27 for 100 AMI in 2003 and 2006, while hospitalization of NQWMI patients increased from 25 for 100 to 56 for100 AMI. There was increasing trend in PCI procedure rates in both QWMI and NQWMI patients while the trend for CABG procedure rates remained flat in QWMI patients compared to slightly decreasing trends in NQWMI. Conclusions: The increasing trends of NQWMI is in concurrence with increasing trends of diabetes mellitus and hypertension in the population, changes in the diagnostic criteria of AMI and evolution of new treatment patterns of PCI.

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Section: Discussionmentioning

confidence: 99%

Secular trends of hospitalization and in-hospital mortality rates of Q-wave and Non-Q-wave myocardial infarction in US: 1990-2006

Ponna¹,

Pothula

Upadrasta³

2016

Public Health Rev: Int J Public Health Res

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“…A cTnT of greater than 0.1 ng/ml was generally taken as pathological, however in two trials a cut-off point of 0.2 ng/ml was used [23, 25]. …”

Section: Methodsmentioning

confidence: 99%

“…Many clinical trials have addressed the role of cTn measurement in acute coronary syndrome without ST elevation (ACS) [4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25]. A substantial proportion of these trials have, however, had small numbers of patients at a single centre or a limited number of centres, and sample timing and analytical techniques have varied between centres.…”

Section: Introductionmentioning

confidence: 99%

Cardiac Troponins in Suspected Acute Coronary Syndrome

Fleming

Daly²

2001

Cardiology

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We performed a meta-analysis of published trials to determine the predictive value of cardiac troponin I (cTnI) and T (cTnT) levels for adverse events (death and myocardial infarction) in acute coronary syndrome without ST elevation (ACS). The accumulated odds ratio (OR) for adverse events (30 days) in ACS with elevated cTnI (n = 5,759) and cTnT (n = 5,483) was 4.9 (95% confidence interval, CI, 3.9–6.2) and 4.6 (95% CI 3.8–5.5), respectively. Trials that mandated timed serum sampling (6 or more hours after symptom onset) had an improved predictive value for elevated cTnI (n = 2,807, OR 8.8; 95% CI 5.9–13.2) and cTnT (n = 1,990, OR 8.5; 95% CI 5.9–12.5). In conclusion, cTnI and cTnT provide similar information in ACS. The risk of adverse events is 4-fold higher in patients with suspected ACS and elevated serum cTn. For patients with an elevated timed (6-hour) sample the risk is over 8-fold higher.

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Retraction of a paper containing plagiarized material: The prognostic value of serum troponin T in unstable angina. Gökhan Cin V, Gök H, Kaptanoğlu B. Int J Cardiol. 1996 Mar;53(3):237–44

Coats¹

2010

International Journal of Cardiology

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The prognostic value of serum troponin T in unstable angina

Cited by 14 publications

References 30 publications

Secular trends of hospitalization and in-hospital mortality rates of Q-wave and Non-Q-wave myocardial infarction in US: 1990-2006

Secular trends of hospitalization and in-hospital mortality rates of Q-wave and Non-Q-wave myocardial infarction in US: 1990-2006

Cardiac Troponins in Suspected Acute Coronary Syndrome

Retraction of a paper containing plagiarized material: The prognostic value of serum troponin T in unstable angina. Gökhan Cin V, Gök H, Kaptanoğlu B. Int J Cardiol. 1996 Mar;53(3):237–44

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