The prognostic value of arterial stiffness in systolic heart failure

Demir, Şerafettin; Akpınar, Onur; Akkuş, Oğuz; Nas, Kamil; Ünal, İlker; Molnár, F; Demir, Ahmet; Illyés, Miklós; Acartürk, Esmeray

doi:10.5603/cj.2013.0168

Cited by 19 publications

(17 citation statements)

References 38 publications

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“…The brachial AIx is calculated from the difference in amplitude (pressure difference) between the first and reflected second wave in relation to the PP, based on the formula: AIx %=[( P 2 − P 1)/PP] × 100. The brachial AIx levels are defined as normal (<−10%), high (−10% to +10%) and pathological (>+10%) for all age strata [14,15]. Aortic AIx correlates with brachial AIx using the regression equation y =0.506 x + 37.636 [4].…”

Section: Methodsmentioning

confidence: 99%

“…The distance travelled by the waves is assimilated as the distance between the jugulum and the symphysis and measured individually with a tape. Aortic PWV levels are characterized as normal (<9.7 m/s), high (9.7–9.9 m/s) or pathological (>10 m/s) for all age strata, supported by outcome data [14,16]. For data quality control, the standard deviation (S.D.)…”

Section: Methodsmentioning

confidence: 99%

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Prevalence of arterial stiffness and the risk of myocardial diastolic dysfunction in women

et al. 2016

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Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Prevalence of arterial stiffness and the risk of myocardial diastolic dysfunction in women

et al. 2016

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“…Sakuragi et al 15 and Kaji et al 16 found a significant relationship between pro-BNP level and aortic stiffness. Demir et al 3 assessed 98 ischemic cardiomyopathy patients with LVEF ≤35% and NYHA functional class III-IV and revealed a cut off value of 11.06 m/s for PWV as a prognostic factor and predictor of mortality in these patients. Regnault et al 14 investigated 306 patients of EPHESUS trial.…”

Section: Discussionmentioning

confidence: 99%

“…8-12 Some of these studies show that PWV is associated with peak VO2, level of pro-brain natriuretic peptide (BNP) and mortality in patients with HF including those with systolic HF. 3,13-16 …”

Section: Introductionmentioning

confidence: 99%

Does aortic pulse wave velocity have any prognostic significance in advanced heart failure patients?

Dohaei¹,

Taghavi²,

Amin³

et al. 2017

J Cardiovasc Thorac Res

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Introduction: Noninvasive measurement of arterial stiffness by pulse-wave velocity (PWV) has prognostic value in different sub groups of cardiovascular disorders. We aimed to measure the PWV in advanced heart failure (HF) patients with reduced left ventricular ejection fraction (LVEF) and investigate whether it has any prognostic significance in this group of patients. Methods: Between 2013 to 2015 patients with a diagnosis of advanced HF (LVEF ≤ 30%) scheduled for right heart catheterization (RHC) were included in our study. PWV was measured before RHC in each patient using vascular explorer device (Enverdis GmbH) in catheterization laboratory. The patients were subsequently followed for 6 months and their hospitalization or death (composite of all-cause death/hospitalization) were recorded. Results: A total of 50 patients (38 men) were enrolled. The mean (SD) of age was 45 (16) years. The mean PWV was 6.8 m/s. There was no statistically significant correlation between the PWV and the clinical, echocardiographic and RHC data. The PWV was not different in patients with or without composite of all-cause death/hospitalization (7.3 versus 6.3, P > 0.05). In this study cardiac output (CO) (beta = -0.53, P = 0.02, odds ratio = 0.6, 95% CI = 0.4-0.9), pulse pressure (PP) (beta = -0056, P = 0.03, odds ratio=0.95, 95% CI = 0.89-0.99) and age (beta = -0.045, P = 0.05, odds ratio = 0.96, 95% CI = 0.9-1.001) were independent predictors of composite of all-cause death/ hospitalization. Conclusion: In patients with advanced systolic HF, PWV may not be a good prognostic factor and does not have any added value over previous well known prognostic factors.

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“…Arterial stiffness is associated with an increased risk of cardiovascular disease [1] and is a predictor of cardiovascular morbidity and mortality in many clinical conditions including essential hypertension and heart failure [2,3]. Therefore, it is an important and relevant measurement in clinical care.…”

Section: Introductionmentioning

confidence: 99%

A simplified measurement of pulse wave velocity is not inferior to standard measurement in young adults and children

Edgell

Stickland

MacLean

2016

Blood Pressure Monitoring

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The standard measurement of pulse wave velocity (PWV) is restricted by the need for simultaneous tonometry measurements requiring two technicians and expensive equipment, limiting this technique to well-resourced settings. In this preliminary study, we compared a simplified method of pulse wave detection from the finger and toe to pulse wave detection from the carotid and radial arteries using applanation tonometry in children and young adults. We hypothesized that the simplified method of PWV measurement would strongly correlate with the standard measurement in different age groups and oxygen conditions. Participants included (a) boys and girls aged 8-12 years and (b) men and women aged 18-40 years. Participants rested supine while carotid and radial artery pulse waves were measured using applanation tonometry and finger and toe pulse waves were simultaneously collected using a Finometer Midi and a piezo-electric pulse transducer, respectively. These measurements were repeated under hypoxic conditions. Finger-toe PWV measurements were strongly correlated to carotid-radial PWV in adults (R=0.58; P=0.011), but not in children (R=0.056; P=0.610). Finger-toe PWV was sensitive enough to show increases in PWV with age (P<0.0001) and hypoxia in children (P<0.0001) and adults (P=0.003). These results indicate that the simplified measurement of finger-toe PWV strongly correlates with the standard measurement of carotid-radial PWV in adults, but not in children. However, finger-toe PWV can be used in either population to determine changes with hypoxia.

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The prognostic value of arterial stiffness in systolic heart failure

Abstract: Measurement of arterial stiffness is a convenient, inexpensive and reliable method for predicting mortality in patients with advanced heart failure.

Cited by 19 publications

References 38 publications

Prevalence of arterial stiffness and the risk of myocardial diastolic dysfunction in women

Prevalence of arterial stiffness and the risk of myocardial diastolic dysfunction in women

Does aortic pulse wave velocity have any prognostic significance in advanced heart failure patients?

A simplified measurement of pulse wave velocity is not inferior to standard measurement in young adults and children

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