The prognosis of patients on hemodialysis with foot lesions

Abstract

Hemodialysis patients with foot lesions have a poor prognosis, with high rates of mortality and amputation. Prompt assessments of the severity of systemic conditions, such as cardiac ischemia, and focal wound conditions, such as ischemia and infection, are necessary to treat hemodialysis patients with foot lesions.

Outcomes of lower extremity revascularization among the hemodialysis-dependent

“…These results remain within previous literature reported ranges at similar time points (AFS, 15%–23% 2,25,26 and survival, 20%–50% 1,2,4,7,28,29 ) and highlight a lack of temporal improvement in treatment of HD patients with critical limb ischemia.…”

“…1–6 With less than 25% of HD patients with a foot lesion alive at 5 years, the prognosis of a HD patient with peripheral artery disease (PAD) remains worse than most cancers. 7 Furthermore, PAD is a common and growing problem in HD patients. PAD has been shown to affect nearly one-third of patients on HD, 8 and, according to the U.S. Department of Health and Human Services, end-stage renal disease (ESRD) has increased by 600% over the past three decades.…”

Clinical Outcomes After Infrainguinal Bypass Grafting for Critical Limb Ischaemia in Patients with Dialysis-dependent End-stage Renal Failure

“…In other studies, hyperlipidaemia has been reported in 5e23% of patients. 13,16,26 Other reports have shown that myocardial infarction, congestive heart failure, and CAD are predictors of survival. 27,28 The present study showed that non-ambulatory status was one of the negative predictors of limb salvage, AFS, and survival.…”

Clinical Efficacy of Infrapopliteal Endovascular Procedures for Hemodialysis Patients with Critical Limb Ischemia

“…Moreover, as diabetic patients with end-stage renal disease (ESRD) resulting from diabetic nephropathy are increasing annually, HD patients are also increasing. 1 According to the Japanese Society for Dialysis Therapy Annual Report, the total HD population surpassed 300,000 at the end of 2011, with HD patients making up a high proportion of the total population at 0.24%. 2 Peripheral artery disease (PAD) is common among HD patients, and in HD patients it is often detected with the onset of critical limb ischemia (CLI) with recalcitrant ulcers or gangrene.…”