The Prognosis of Localized Scleroderma

Linear Scleroderma with Hemiatrophy: Report of Three Cases Associated with Collagen-Vascular Disease

“…Curtiss and Janssen [2] reported on the prognosis of 115 patients with localized scleroderma, 33 with the linear type. Six (5.7%) developed systemic scleroderma.…”

Scleroderma: Nomenclature, etiology, pathogenesis, prognosis, and treatments: Facts and controversies

“…[27][28][29] Examination for sclerodactyly, Raynaud's phenomenon, and nailfold capillary changes at presentation is not thoroughly documented in all nine cases, raising the possibility that at least some of these cases were incorrectly diagnosed with morphea at presentation. Large cohorts of patients with morphea have reported no transitions to systemic sclerosis, 3,30 further supporting that morphea and systemic sclerosis are distinct diseases.…”

Coexistence of Morphea and Systemic Sclerosis

“…Because Raynaud's phenomenon and sclerodactyly are not observed in patients with morphea, morphea is generally considered to be a different entity from SSc. There have been previous reports of SSc associated with morphea [1][2][3][4]. Jablonska et al [1] suggested that morphea and SSc were manifestations of essentially the same basic process, and Curtis and Jansen [2] reported that SSc was present in 6 of 106 morphea patients, suggesting progres sion from morphea to SSc.…”

“…There have been previous reports of SSc associated with morphea [1][2][3][4]. Jablonska et al [1] suggested that morphea and SSc were manifestations of essentially the same basic process, and Curtis and Jansen [2] reported that SSc was present in 6 of 106 morphea patients, suggesting progres sion from morphea to SSc. According to Spencer [5], how ever, the so-called transition from morphea to SSc may in fact have been SSc originally mistakenly identified as mor phea.…”