The Prognosis of Generalized Pustular Psoriasis Terence

Ryan, John F.; Baker, Harvey

doi:10.1111/j.1365-2133.1971.tb14044.x

Cited by 100 publications

(76 citation statements)

References 3 publications

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“…The pro vocative effect of recurrent tonsillitis on GPP has been reported by Ryan and Baker [13] and the beneficial effect of tonsillectomy on the course of psoriasis in children has been demonstrated by Nyfors and Lemholt [9], We agree with these authors that one should be aware of the triggering effect of up per respiratory infections.…”

Section: Discussioncontrasting

confidence: 28%

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Generalized Pustular Psoriasis in a Child

Kerkhof¹

1985

Dermatology

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Section: Discussioncontrasting

confidence: 28%

“…The relation between GPP and ACH has already been described by Ryan and Baker [13], who showed that GPP can evolve from ACH. The prognosis of these patients is very bad.…”

Section: Discussionmentioning

confidence: 94%

Generalized Pustular Psoriasis in a Child

Kerkhof¹

1985

Dermatology

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“…The attacks may be induced in some cases by triggering factors such as infections, drugs, sunlight, or pregnancy. 1,2 Since the first description of the disease in 1910, there have been reports of patients with GPP who present with extracutaneous manifestations, which consist mostly of mucous membranes lesions and arthritis. 3,4 Evidence of liver involvement of unknown physiopathology has been suggested in isolated case reports.…”

Section: G Eneralized Pustular Psoriasis (Gpp) Of the Vonmentioning

confidence: 99%

High frequency of cholestasis in generalized pustular psoriasis: Evidence for neutrophilic involvement of the biliary tract

et al. 2004

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Generalized pustular psoriasis is a rare form of psoriasis that is sometimes associated with extracutaneous manifestations. Evidence for biliary involvement has been suggested in isolated cases. We investigated the prevalence and nature of liver abnormalities occurring in this disease. Twenty-two patients consecutively admitted for generalized pustular psoriasis who underwent liver biological tests at the time of the attack and during the following weeks were included. Twenty patients (90%) had at least one abnormal biological liver parameter. Eleven patients (50%) had pronounced abnormalities: jaundice (4/22), gammaglutamyl transferase higher than 5 times the normal value (10/22), alkaline phosphatase higher than twice the normal value (7/22), and/or aminotransferases higher than 3 times the normal value (7/22). These abnormalities returned to normal range at the time of remission of pustular psoriasis, suggesting that severe liver abnormalities could be associated with severe cutaneous disease. Neutrophilic cholangitis was observed on liver biopsy. Persistent magnetic resonance cholangiopancreatography features similar to those observed in sclerosing cholangitis were found in 3 of the 4 patients studied. No causal factor other than pustular psoriasis could be identified. In conclusion, our results demonstrate the high frequency of liver abnormalities in patients with generalized pustular psoriasis. Biliary involvement related to neutrophilic cholangitis should be added to the spectrum of extracutaneous manifestations of this disease, and physicians should be aware of such a complication. (HEPATOLOGY 2004;40:452-458.)

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“…In SSSS, a superficial cleavage through the upper layer of the epidermis is caused by a staphylococcal-phage group II exotoxin, which is probably excreted by the mature kidney [ [84][85][86][87][88]. Its exact pathogenesis remains unknown; however, the factors that trigger an episode of generalized pustular psoriasis of von Zumbusch include topical or oral steroid use [84,[86][87][88]89], lithium [90], butazones [91], pregnancy [84], infections [84,86], ultraviolet irradiation [92,93], emo-. tional factors [87], and hypocalcemia [94].…”

mentioning

confidence: 99%

Dermatologic Problems in the Intensive Care Unit: Part I

Berman

Silvestri

1986

J Intensive Care Med

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Skin disorders are present in many patients hospitalized in the intensive care unit. They range in severity from being the reason for admission to being a nuisance acquired during care These cutaneous problems have been categorized into four groups: (1) serious skin diseases that may incur life-threatening complications; (2) subtle skin findings associated with systemic disorders that may be characterized by critical events; (3) prominent cutaneous manifestations that accompany lifethreatening systemic diseases: and (4) skin disorders that develop as complications during intensive care. Diseases in the first category are discussed in this article.

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The Prognosis of Generalized Pustular Psoriasis Terence

Cited by 100 publications

References 3 publications

Generalized Pustular Psoriasis in a Child

Generalized Pustular Psoriasis in a Child

High frequency of cholestasis in generalized pustular psoriasis: Evidence for neutrophilic involvement of the biliary tract

Dermatologic Problems in the Intensive Care Unit: Part I

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