The Profile of Glycated Hemoglobin in Non-Diabetic Pregnant Women with Preeclampsia: A Case-Control Study in Kinshasa, the Democratic Republic of Congo

Abstract

Background: A disturbed glucose metabolism is quite common during pregnancy. It is due to the diabetogenic potential of pregnancy and responsible for many obstetric complications. The glycated hemoglobin is one of the markers used to depict these disorders. Higher concentrations of this marker would be associated with unfavorable results of pregnancy. Objective: To describe the profile of HbA1c in non-diabetic preeclamptic pregnant women and to establish the association between the values of this marker and the maternal and fetal complications. Materials and Method: This is a case-control study of 142 pregnant women in their second and third trimester. They were followed in the maternity hospitals of University Clinics and the General Reference Hospital in Kinshasa, Democratic Republic of Congo between May and October 2019. The sampling of preeclamptic pregnant women was exhaustive.

A prospective study on HbA1c levels in patients without GDM and its correlation with pregnancy outcome

“…In a study conducted by Mane et al 26 the incidence of macrosomia in the newborns was found to be raised (16.7% from 5.9%) in the participants with HbA1c of ≥5.9% also they found that they had an elevated risk of preeclampsia (9.32% vs. 3.9%). In our present study we did not include variables like macrosomia or preeclampsia but, 17 5.29 Nielsen et al 18 5.0 Yu et al 19 5.0 Bhavadharani et al 20 4.9 Versantvoort et al 21 4.9…”