The process of metastasis

Scanlon, Edward F.; Murthy, Satya

doi:10.3322/canjclin.41.5.301

Cited by 15 publications

(3 citation statements)

References 19 publications

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“…In the literature it has been shown that despite the fact that there is often a relatively long interval between time of primary surgery and time of initial metastasis (2-49 months), prognosis with such abdominal wall metastatic disease is poor [1,2,7]. In our study, the interval between time of primary surgery and abdominal wall metastatic disease was 34 months and survival after the first abdominal wall metastasis resection was 10 months.…”

Section: Discussionmentioning

confidence: 44%

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Abdominal wall metastasis following treatment of rectal cancer

et al. 2004

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We present a 60-year-old man with a metastatic subcutaneous lump in the left lower quadrant of the abdomen, from rectal cancer, which was treated three years earlier with low anterior resection of the rectum. Excision of the abdominal wall metastasis was accomplished with negative histological margins, but six months later a new abdominal wall mass was detected. The patient underwent surgery again, in which the abdominal wall metastasis was resected en bloc with adherent portion of small bowel, along with inguinal lymph node dissection. The patient's condition deteriorated 10 months after the initial diagnosis, presenting again with abdominal wall cancer and dying from disseminated peritoneal disease.

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Section: Discussionmentioning

confidence: 44%

“…Thus, a substratum for adhesion, a protective barrier against host defence systems and a source of nutrition are all provided at the wound site. In addition, the production of tumour necrosis factor (TNF) may also play an important role in explaining the propensity for metastasis to occur at sites of cellular damage [5][6][7].…”

Section: Discussionmentioning

confidence: 99%

Abdominal wall metastasis following treatment of rectal cancer

et al. 2004

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“…Andererseits konnten vitale Tumorzellen im Venenblut von Patienten mit malignen Erkrankungen nachgewiesen werden. Der Nachweis allein sei jedochweder ein Hinweis auf deren aggressives Verhalten, noch ein prognostisch verwertbarer Faktor (9,16,42,44). Zum Einsatz eines MAT-Gerätes bei der TUR-Prostata gibt es bezüglich der Tumorzellen keine wissenschaftlich gesicherten Erkenntnisse.…”

Section: Bewertung Der Tumorzell-kontaminationunclassified