The Problem of the Colorectal Anastomosis

Ionescu, S

doi:10.5772/intechopen.100302

Cited by 2 publications

(2 citation statements)

References 21 publications

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“…Problems in Physics, and in general, should not be solved in isolation (e.g. [33] The most important consequence is that it explains theoretically, based on the accepted SM, that Gravity is of quantum origin, due to quark structure and nucleon spin-spin orientation dependent, which is confirmed by experiment [5] and implemented technologically, as far as we can tell from observation and historical data.…”

Section: Beyond the Standard Modelmentioning

confidence: 99%

Adapted Metrics for a Modified Coulomb/Newton’s Potential

Ionescu,

Pripoae,

Pripoae

2023

JHEPGC

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Modified Theories of Gravity include spin dependence in General Relativity, to account for additional sources of gravity instead of dark matter/energy approach. The spin-spin interaction is already included in the effective nuclear force potential, and theoretical considerations and experimental evidence hint to the hypothesis that Gravity originates from such an interaction, under an averaging process over spin directions. This invites to continue the line of theory initiated by Einstein and Cartan, based on tetrads and spin effects modeled by connections with torsion. As a first step in this direction, the article considers a new modified Coulomb/Newton Law accounting for the spin-spin interaction. The physical potential is geometrized through specific affine connections and specific semi-Riemannian metrics, canonically associated to it, acting on a manifold or at the level of its tangent bundle. Freely falling particles in these "toy Universes" are determined, showing an interesting behavior and unexpected patterns.

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Section: Beyond the Standard Modelmentioning

confidence: 99%

Adapted Metrics for a Modified Coulomb/Newton’s Potential

Ionescu,

Pripoae,

Pripoae

2023

JHEPGC

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“…Most colorectal procedures involve the resection of a target pathology followed by the restoration of gastrointestinal continuity through the creation of an anastomosis. An anastomosis can be defined as a hand-sewn or stapled connection between two tubular structures ( 4 ). As with any surgical intervention, the creation of an anastomosis does not come without risk.…”

Section: Introductionmentioning

confidence: 99%

Colorectal anastomotic leakage: a narrative review of definitions, grading systems, and consequences of leaks

Rennie,

Sharma,

Helwa

2024

Front. Surg.

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BackgroundAnastomotic leaks (ALs) are a significant and feared postoperative complication, with incidence of up to 30% despite advances in surgical techniques. With implications such as additional interventions, prolonged hospital stays, and hospital readmission, ALs have important impacts at the level of individual patients and healthcare providers, as well as healthcare systems as a whole. Challenges in developing unified definitions and grading systems for leaks have proved problematic, despite acknowledgement that colorectal AL is a critical issue in intestinal surgery with serious consequences. The aim of this study was to construct a narrative review of literature surrounding definitions and grading systems for ALs, and consequences of this postoperative complication.MethodsA literature review was conducted by examining databases including PubMed, Web of Science, OVID Embase, Google Scholar, and Cochrane library databases. Searches were performed with the following keywords: anastomosis, anastomotic leak, colorectal, surgery, grading system, complications, risk factors, and consequences. Publications that were retrieved underwent further assessment to ensure other relevant publications were identified and included.ResultsA universally accepted definition and grading system for ALs continues to be lacking, leading to variability in reported incidence in the literature. Additional factors add to variability in estimates, including differences in the anastomotic site and institutional/individual differences in operative technique. Various groups have worked to publish guidelines for defining and grading AL, with the International Study Group of Rectal Cancer (ISGRC/ISREC) definition the current most recommended universal definition for colorectal AL. The burden of AL on patients, healthcare providers, and hospitals is well documented in evidence from leak consequences, such as increased morbidity and mortality, higher reoperation rates, and increased readmission rates, among others.ConclusionsColorectal AL remains a significant challenge in intestinal surgery, despite medical advancements. Understanding the progress made in defining and grading leaks, as well as the range of negative outcomes that arise from AL, is crucial in improving patient care, reduce surgical mortality, and drive further advancements in earlier detection and treatment of AL.

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The Problem of the Colorectal Anastomosis

Cited by 2 publications

References 21 publications

Adapted Metrics for a Modified Coulomb/Newton’s Potential

Adapted Metrics for a Modified Coulomb/Newton’s Potential

Colorectal anastomotic leakage: a narrative review of definitions, grading systems, and consequences of leaks

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