The Problem of Information Transfer from the Nucleic Acids to Proteins

Gamow, George; Rich, Alexander; Yčas, Martynas

doi:10.1016/b978-1-4832-3110-5.50006-6

Cited by 100 publications

(28 citation statements)

References 48 publications

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“…It suggested, that life developed somewhere in the universe and spread in the cosmos, even to the Earth, as DNA trapped in cosmic debris. In this case only a short part of biological evolution is available for us; we can see trends, suggest necessary events (like the AT-only nucleic acids [8] and overlapping translation [13][14][15]) without the possibility to find remains of these evolutionary steps.…”

Section: The Possible Origin Of the Genetic Codementioning

confidence: 99%

“…In the years immediately following the proposal of the structure for dsDNA, George Gamow suggested a so-called "diamond code" to explain the connection and information transfer between DNA and proteins [13][14][15]. In his model the nucleic acid bases from 20 different cavities into which the 20 different amino acids fit specifically.…”

Section: The Possible Origin Of the Genetic Codementioning

confidence: 99%

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Evolution of the Genetic Code ? Some Novel Aspects

Biro¹

2014

J Theor Comput Sci

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Section: The Possible Origin Of the Genetic Codementioning

confidence: 99%

Section: The Possible Origin Of the Genetic Codementioning

confidence: 99%

Evolution of the Genetic Code ? Some Novel Aspects

Biro¹

2014

J Theor Comput Sci

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“…Gamow (1954b) argued that this structural difference was functionally irrelevant because most amino acids were bilaterally symmetric. Their side chain could be turned around the Cα-bond by 180° (Gamow et al 1956), 10 which would allow them to bind to both cavities. So, 9 I thank a reviewer for emphasising this contrast.…”

Section: Functional Equivalencementioning

confidence: 99%

Physical models and embodied cognition

Stegmann

2018

Synthese

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Philosophers have recently paid more attention to the physical aspects of scientific models. The attention is motivated by the prospect that a model's physical features strongly affect its use and that this suggests re-thinking modelling in terms of extended or distributed cognition. This paper investigates two ways in which physical features of scientific models affect their use and it asks whether modelling is an instance of extended cognition. I approach these topics with a historical case study, in which scientists kept records not only of their findings, but also of some the mental operations that generated the findings. The case study shows how scientists can employ a physical model (in this case diagrams on paper) as an external information store, which allows alternating between mental manipulations, recording the outcome externally, and then feeding the outcome back into subsequent mental manipulations. The case study also demonstrates that a models' physical nature allows replacing explicit reasoning with visuospatial manipulations. I argue, furthermore, that physical modelling does not need to exemplify a strong kind of extended cognition, the sort for which external features are mereological parts of cognition. It can exemplify a weaker kind, instead.

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“…First the information stored in DNA molecules are transmitted to the molecules of RNA (Ribonucleic Acid) which move out into the cytoplasm of the cell and form the so-called microsomes. (Gamow, 1955: 1)…”

Section: The Early Years and The Introduction Of The Metaphor Of The mentioning

confidence: 99%

Communicating novel and conventional scientific metaphors: a study of the development of the metaphor of genetic code

Knudsen

2005

Public Underst Sci

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To cite this version:Susanne Knudsen. Communicating novel and conventional scientific metaphors: a study of the development of the metaphor of genetic code. Public Understanding of Science, SAGE Publications, 2005, 14 (4), pp.373-392. <10.1177/0963662505056613>. Communicating novel and conventional scientific metaphors: a study of the development of the metaphor of genetic code Susanne KnudsenMetaphors are more popular than ever in the study of scientific reasoning and culture because of their innovative and generative powers. It is assumed, that novel scientific metaphors become more clear and well-defined, as they become more established and conventional within the relevant discourses. But we still need empirical studies of the career of metaphors in scientific discourse and of the communicative strategies identifying a given metaphor as either novel or conventional. This paper presents a case study of the discursive development of the metaphor of "the genetic code" from the introduction of the metaphor to its establishment as an entire network of interrelated conventional metaphors. Not only do the strategies in communicating the metaphor change as the metaphor becomes more established within the discourse, but the genres in which the metaphor is developed and interpreted change too during the career of the metaphor. Whereas the standard scientific article is central in experimentally researching and explaining the metaphor, a mixture of more popular scientific genres dominates in the innovative conceptual development of the metaphor.

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The Problem of Information Transfer from the Nucleic Acids to Proteins

Cited by 100 publications

References 48 publications

Evolution of the Genetic Code ? Some Novel Aspects

Evolution of the Genetic Code ? Some Novel Aspects

Physical models and embodied cognition

Communicating novel and conventional scientific metaphors: a study of the development of the metaphor of genetic code

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