The Primary Outcomes and Epidemiological and Clinical Features of Coronavirus Disease 2019 (COVID-19) in Iran

Vahedian‐Azimi, Amir; Ashtari, Sara; Alishiri, Gholam Hossein; Shahriary, Alireza; Saberi, Mohsen; Rahimi–Bashar, Farshid; Panahi, Yunes; Samadinia, Hossein; Ferdosi, Mojtaba; Jafari, Iman; Vahedi, Ensieh; Ghazvini, Ali; Nikpouraghdam, Mohamad; Gohari-Moghadam, Keivan; Izadi, Morteza; Jonaidi-Jafari, Nematollah; Shojaee, Saeedeh; Aghdaei, Hamid Asadzadeh; Pourhoseingholi, Mohamad Amin; Sahebkar, Amirhossein

doi:10.1007/978-3-030-59261-5_17

Cited by 2 publications

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References 20 publications

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“…Iran has been among the most prone countries to the virus, especially in the Middle East [ 4 – 7 ]. Approximately 3 851 162 COVID-19 patients and 90 344 deaths (mortality rate: 2.34%) have been recorded in Iran until July 30, 2021 [ 8 ].…”

Section: Introductionmentioning

confidence: 99%

Epidemiology of COVID-19 in Tehran, Iran: A Cohort Study of Clinical Profile, Risk Factors, and Outcomes

Hatamabadi

Sabaghian

Sadeghi

et al. 2022

BioMed Research International

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Background. The outbreak of coronavirus disease 2019 (COVID-19) dates back to December 2019 in China. Iran has been among the most prone countries to the virus. The aim of this study was to report demographics, clinical data, and their association with death and CFR. Methods. This observational cohort study was performed from 20th March 2020 to 18th March 2021 in three tertiary educational hospitals in Tehran, Iran. All patients were admitted based on the WHO, CDC, and Iran’s National Guidelines. Their information was recorded in their medical files. Multivariable analysis was performed to assess demographics, clinical profile, outcomes of disease, and finding the predictors of death due to COVID-19. Results. Of all 5318 participants, the median age was 60.0 years, and 57.2% of patients were male. The most significant comorbidities were hypertension and diabetes mellitus. Cough, dyspnea, and fever were the most dominant symptoms. Results showed that ICU admission, elderly age, decreased consciousness, low BMI, HTN, IHD, CVA, dialysis, intubation, Alzheimer disease, blood injection, injection of platelets or FFP, and high number of comorbidities were associated with a higher risk of death related to COVID-19. The trend of CFR was increasing (WPC: 1.86) during weeks 25 to 51. Conclusions. Accurate detection of predictors of poor outcomes helps healthcare providers in stratifying patients, based on their risk factors and healthcare requirements to improve their survival chance.

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Section: Introductionmentioning

confidence: 99%

Epidemiology of COVID-19 in Tehran, Iran: A Cohort Study of Clinical Profile, Risk Factors, and Outcomes

Hatamabadi

Sabaghian

Sadeghi

et al. 2022

BioMed Research International

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“…The epidemic of Coronavirus disease-2019 (COVID-19), caused by Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2), which was first discovered in Wuhan, China, quickly became a global pandemic 1 , 2 . Acute respiratory distress syndrome (ARDS), a life-threatening form of respiratory failure, is common among COVID-19 patients 3 , 4 .…”

Section: Introductionmentioning

confidence: 99%

1-year survival rate of SARS-CoV-2 infected patients with acute respiratory distress syndrome based on ventilator types: a multi-center study

Mahmoodpoor

Gohari-Moghadam

Rahimi–Bashar

et al. 2023

Sci Rep

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The aim of this study was to evaluate the association between types of ventilator and the one-year survival rate of patients with acute respiratory distress syndrome (ARDS) due to SARS‑CoV-2 infection. This multi-center, retrospective observational study was conducted on 1078 adult patients admitted to five university-affiliated hospitals in Iran who underwent mechanical ventilator (MV) due to ARDS. Of the 1078 patients, 781 (72.4%) were managed with ICU ventilators and 297 (27.6%) with transport ventilators. Overall mortality was significantly higher in patients supported with transport ventilator compared to patients supported with ICU ventilator (16.5% vs. 9.3% P = 0.001). Regression analysis revealed that the expected hazard overall increased with age (HR: 1.525, 95% CI 1.112–1.938, P = 0.001), opacity score (HR: 1.448, 95% CI 1.122–2.074, P = 0.001) and transport ventilator versus ICU ventilator (HR: 1.511, 95% CI 1.143–2.187, P = 0.029). The Kaplan–Meier curves of survival analysis showed that patients supported with ICU ventilator had a significantly higher 1-year survival rate (P = 0.001). In MV patients with ARDS due to COVID-19, management with non-ICU sophisticated ventilators was associated with a higher mortality rate compared to standard ICU ventilators. However, more studies are needed to determine the exact effect of ventilator types on the outcome of critically ill patients.

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The Primary Outcomes and Epidemiological and Clinical Features of Coronavirus Disease 2019 (COVID-19) in Iran

Cited by 2 publications

References 20 publications

Epidemiology of COVID-19 in Tehran, Iran: A Cohort Study of Clinical Profile, Risk Factors, and Outcomes

Epidemiology of COVID-19 in Tehran, Iran: A Cohort Study of Clinical Profile, Risk Factors, and Outcomes

1-year survival rate of SARS-CoV-2 infected patients with acute respiratory distress syndrome based on ventilator types: a multi-center study

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