The prevention of gambling bahavior in switzerland

Abstract

The aim of this study is to test the hypothesis that coadjuvant treatment with SSRI and topiramate would improve the outcome of patients with comorbid OCD and impulsive behaviour disorders. Methods: We will describe two clinical cases admitted to our Psychiatric Hospitalization Unit. Case 1 is a 39 years old female diagnosed with OCD, borderline personality disorder and alcohol dependence and case 2 is a 38 years old male with OCD, mixed personality disorder and cocaine abuse. Results: Treatment with topiramate (range dosage: 250-400 mg/ daily) as well as SSRI (paroxetine 40 mg/daily-case 1; sertraline 200 mg/daily-case 2) improved affective instability and impulsive symptoms in both patients. Topiramate was well tolerated without important side effects. Conclusions: Topiramate could be an interesting alternative in the coadjuvant treatment of OCD with impulsive features.