The Prevalence of Thyroid Disease in Patients Admitted to a Geriatric Department

Jefferys, Peter

doi:10.1093/ageing/1.1.33

Cited by 30 publications

(12 citation statements)

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“…In this longitudinal study no new cases of thyroid disease were diagnosed, contrasting sharply with the results of previously re ported surveys carried out in the 1970s [ 1,2], The discrepancy can probably be explained by the differences in the severity of illness in the patients studied, the study design, the type of tests used and the heightened aware ness of the prevalence of thyroid disease in the elderly population. The finding of known and treated thyroid disease in 3.3% of our study group supports the latter.…”

Section: Discussioncontrasting

confidence: 99%

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Longitudinal Study of Thyroid Function in Acutely Ill Elderly Patients Using a Sensitive TSH Assay-Defer Testing until Recovery

Bhakri

Fisher²,

Khadri³

et al. 1990

Gerontology

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A prospective longitudinal study of thyroid function was conducted in 180 consecutive admissions to an acute geriatric unit. The rest strategy included assay of TSH and TRH testing when appropriate. On admission TSH was suppressed ( < 0.1 mU/l) in 17 patients (9.4%) and elevated ( > 4.0 mU/l) in 8 (4.4%). Follow-up of these initial abnormalities showed resolution in almost all cases. Our findings suggest that acute illness may interfere with the hypothalamic-pituitary-thyroid axis, causing either temporary suppression or stimulation of TSH release. Although no new cases of thyroid disease were diagnosed, the prevalence of established dysfunction was 3.3% (2.7% hypothyroid; 0.6% hyperthyroid). To avoid misleading results, testing of thyroid dysfunction should be delayed until recovery from illness.

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Section: Discussioncontrasting

confidence: 99%

“…Previously reports of a high prevalence of occult thyroid disease in elderly patients ad mitted to hospital [1,2] have produced ad vocates for a policy of routine screening of such patients [3]. However, in acute nonendocrine illness conventional thyroid and other endocrine function tests may give rise to a significant number of misleading results [4].…”

mentioning

confidence: 99%

Longitudinal Study of Thyroid Function in Acutely Ill Elderly Patients Using a Sensitive TSH Assay-Defer Testing until Recovery

Bhakri

Fisher²,

Khadri³

et al. 1990

Gerontology

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“…Hyperthyroidism in the elderly frequently has an atypical clinical presentation (Jefferys, 1972;Green, 1973), and is associated with nodular rather than diffuse goitres (McKeown, 1965). Of our patients with hyperthyroid func tion tests, half had nodular glands.…”

Section: Discussionmentioning

confidence: 75%

“…Abnormal thyroid function is demonstrable in 2-3% of elderly in-patients (Jefferys, 1972;Bahemuka and Hodkinson, 1975;Kind and Ghosh, 1976). It was, therefore, decided to study the thyroid glands obtained at post mortem examination from patients admitted to the geriatric unit at Northwick Park Hospital during [1970][1971][1972][1973] and attempt to relate the morphological findings to thyroid function studies.…”

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confidence: 99%

A Clinico-Pathological Survey of Thyroid Glands in Old Age

Denham

Wills²

1980

Gerontology

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A quarter of the thyroid glands obtained at post-mortem examination from a group of elderly inpatients were nodular. There was a significant preponderance of women with goitre, but no relationship to age. The incidence of hyperthyroidism was increased in patients with nodular glands. There was no correlation between the weight of the thyroid gland, the age of the patient and the free-thyroxine index. Histological examination of macroscopic ally normal glands showed tiny follicles, microscopic colloid nodules and fibrosis. Nodular glands had the features of long-standing colloid nodular goitre. Focal lymphocytic thyroiditis was observed in a fifth of the glands. Microscopic evidence of altered function was common but could not always be correlated with the results of the thyroid function studies.

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“…Tests of thyroid function have been performed routinely [Jefferys, 1972] and provide a number of examples of drug effects. Our earlier ex perience was in using protein-bound iodine (PBI) and the T3 uptake test in combination.…”

Section: Thyroid Function Testsmentioning

confidence: 99%

Biochemical Side Effects of Drugs in the Elderly

Hodkinson¹

1974

Geront clin

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The Prevalence of Thyroid Disease in Patients Admitted to a Geriatric Department

Cited by 30 publications

References 0 publications

Longitudinal Study of Thyroid Function in Acutely Ill Elderly Patients Using a Sensitive TSH Assay-Defer Testing until Recovery

Longitudinal Study of Thyroid Function in Acutely Ill Elderly Patients Using a Sensitive TSH Assay-Defer Testing until Recovery

A Clinico-Pathological Survey of Thyroid Glands in Old Age

Biochemical Side Effects of Drugs in the Elderly

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