The Prevalence of Severe Asthma and Low Asthma Control Among Danish Adults

Utilization and Costs of Severe Uncontrolled Asthma in a Managed-Care Setting

“…24 More recently, a nationwide Danish adult study reported a severe asthma prevalence of 8.1% among asthmatics based on a high level of controller medications. 25 A more comprehensive Dutch study that applied pharmacy databases of 500,000 patients and questionnaires to a random sample noted a 3.6% (95% CI, 3.0% to 4.1%) prevalence of severe refractory asthma (10.4 patients per 10,000 inhabitants) among asthmatics based on high-dose ICS/LABA combination or medium-high dose ICS/LABA and oral corticosteroids. 2 Differences in the reported prevalence of severe asthma probably relate to differences in more stringent diagnostic criteria, populations studied, and available asthma care management.…”

Nordic consensus statement on the systematic assessment and management of possible severe asthma in adults

“…Systematic assessment is also important in ensuring that novel expensive treatments are only used in patients likely to respond. Unfortunately only a minority of subjects considered having severe asthma have been systematically assessed [9]. There are no studies formally assessing the best way to organize the management of severe asthma, but based on current understanding and recommendations by other societies [103] we recommend the following.…”

“…The Nordic Countries share similar healthcare systems, as well as a similar demography: Based on the reported prevalence rates of severe asthma [9,10], approximately 33,000 patients among the 22 million inhabitants of the Nordic countries can be estimated to suffer from severe asthma.…”

Emerging corticosteroid agonists for the treatment of asthma

“…The remaining patients exhibit persistent disease requiring daily treatment. About 10% of the asthma cases can be classified as a severe, difficult-to-treat phenotype [17,18].…”