The Prevalence of Secondary and Curable Hypertension

Danielson, Mats; Dammström, Bo-Göran

doi:10.1111/j.0954-6820.1981.tb11628.x

Cited by 67 publications

(21 citation statements)

References 10 publications

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“…OSA and PA were the most common secondary causes and coexisting diseases of hypertension among hypertensive patients. Previous studies described that prevalence of secondary causes of hypertension ranges from 4.7% to 10.5% [18–20] and that the most common secondary causes of hypertension are RPD and RAS [21]. In these previous studies, however, OSA was not included.…”

Section: Discussionmentioning

confidence: 99%

Detection of Secondary Causes and Coexisting Diseases in Hypertensive Patients: OSA and PA Are the Common Causes Associated with Hypertension

Wang

Yao

et al. 2017

BioMed Research International

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Background Since the control rate of blood pressure is lower in mainland China, the aim of this study is to investigate the proportion of secondary causes and coexisting diseases of hypertension in hypertensive patients. Methods Data on consecutive patients with hypertension who visited the Hypertension Center. Diseases were detected using an established strict screening protocol. Results Detection rate of secondary causes and coexisting diseases of hypertension was 39.5% among 3003 hypertensive patients. Obstructive sleep apnea (OSA) was the most common, accounting for 24.7% of patients, followed by primary aldosteronism (PA) (5.8%) and PA + OSA (4.9%). Endocrine hypertension accounted for 12.1% of patients, including 10.7% of patients with PA, 1.1% with hypothyroidism, 0.1% with pheochromocytoma, 0.1% with Cushing's syndrome, and 0.1% with hyperthyroidism, respectively. Those who smoke, those who are obese, and those who have diabetes accounted for 31.3%, 27.5%, and 16.6% of total patients, respectively. There were overlapping conditions in secondary causes and coexisting diseases of hypertension. OSA was the most common in each age- and BMI-stratified group. Conclusion Findings from the current study suggest an increasing frequency of secondary forms of hypertension, highlighting the burden of OSA and PA in hypertensive patients.

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Section: Discussionmentioning

confidence: 99%

Detection of Secondary Causes and Coexisting Diseases in Hypertensive Patients: OSA and PA Are the Common Causes Associated with Hypertension

Wang

Yao

et al. 2017

BioMed Research International

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“…as having hypertension in a primary care clinic, 95% have primary or essential hypertension, and only 5% have a secondary cause. 35 In a study at a hypertension clinic, secondary hypertension accounted for only 9% of all patients seen. 36 Severe or difficult-to-control hypertension, hypertension that suddenly develops or suddenly worsens, or hypertension that is associated with other clinical findings may indicate secondary hypertension.…”

Section: Phosphate-containing Bowel Preparations Should Be Used With mentioning

confidence: 99%

The Top 10 Things Nephrologists Wish Every Primary Care Physician Knew

Paige

Nagami

2009

Mayo Clinic Proceedings

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Renal disease is commonly encountered by primary care physicians during their day-to-day visits with patients. Common renal disorders include hypertension, proteinuria, kidney stones, and chronic kidney disease. Despite their prevalence, many physicians may be unfamiliar with the diagnosis and initial treatment of these common renal disorders. Early recognition and intervention are important in slowing the progression of chronic kidney disease and preventing its complications. The evidence-based pearls in this article will help primary care physicians avoid common pitfalls in the recognition and treatment of such disorders and guide their decision to refer their patients to a specialist. © 2009 Mayo Foundation for Medical Education and Research CONCISE REVIEW FOR CLINICIANSAfter reviewing this article, the reader should be able to (1)

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“…1,2 Owing to recent developments in diagnostic imaging, more cases with APA have been detected, and its prevalence is now several percent of all hypertensive cases. 3,4 Mesangial proliferative glomerulonephritis (MesPGN) is a histological fi nding frequently identifi ed in IgA nephropathy (IgAN), but it can also be observed as systemic disease-associated glomerular lesions.…”

Section: Introductionmentioning

confidence: 99%

Mesangial proliferative glomerulonephritis with aldosterone-producing adenoma

et al. 2007

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We describe a case of mesangial proliferative glomerulonephritis (MesPGN), the clinical symptoms of which were exacerbated by aldosterone-producing adenoma (APA). A 45-year-old man, who had had a history of hypertension for several years, presented with renal derangement, with serum creatinine at its upper normal limit and with microhematuria and proteinuria. He also presented with hypokalemia, with a plasma aldosterone concentration at its upper normal limit and plasma renin activity at its lower normal limit. After the administration of spironolactone, we resected his left adrenal gland, which had a nodular lesion as well as aldosterone hypersecretion. The treatment normalized his arterial blood pressure and serum potassium concentration. Although his proteinuria disappeared with the reduction in arterial blood pressure, the microhematuria continued. The administration of losartan because of the histological finding of MesPGN reduced the amount of hematuria. A dissociated response of hematuria and proteinuria to antihypertensive treatment indicated that MesPGN was coincidental with APA.

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The Prevalence of Secondary and Curable Hypertension

Cited by 67 publications

References 10 publications

Detection of Secondary Causes and Coexisting Diseases in Hypertensive Patients: OSA and PA Are the Common Causes Associated with Hypertension

Detection of Secondary Causes and Coexisting Diseases in Hypertensive Patients: OSA and PA Are the Common Causes Associated with Hypertension

The Top 10 Things Nephrologists Wish Every Primary Care Physician Knew

Mesangial proliferative glomerulonephritis with aldosterone-producing adenoma

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