Abstract:This study determined the prevalence of Rheumatoid arthritis in elderly people that attended pilgrimage center, Elele Rivers state, Nigeria. A total of 200 subjects attending the pilgrimage center were examined for Rhematoid Factor using Latex agglutination method. The data was subjected to statistical analysis using Statistical Package for Social Sciences (SPSS) version 16.0. A prevalence of 4% was seen in the female subjects within the age bracket of 65-80 years and a prevalence of 1% was seen in the male su… Show more
“…The results of a study conducted by Eledo et al [9] showed that positive Rheumatoid Arthritis occurred significantly in 5% of the population. The prevalence of this population is 4% in female subjects in the age range of 65-80 years and 1% in men in the age range of 61-70 years.…”
Section: Rheumatoid Arthritis In Elderly Womenmentioning
Rheumatoid Arthritis (RA) is an autoimmune disease that causes joint inflammation. Elderly, especially women are more susceptible to RA due to hormonal factors. RA patient often feel inconvenient during physical activity because of pain in their joint. The purpose of this study was to determine the effect of physical activity on elderly woman with Rheumatoid Arthritis. This research is a literature study using traditional review method. Journal article studies were searched in Google Scholar, OneSearch Indonesia, and Garuda in Bahasa and English language that published online from 2012-2022 according to keywords. Of 9.030 studies from databases identified 30 journal studies were included. Literature studies show that the prevalence of elderly women with RA is higher than men. These studies also shows that severity of RA affects the ability of elderly to do a physical activity and physical activity itself influences reducing pain and preventing the severity of RA. The conclusion of this study is that the prevalence of elderly women with RA is higher than men and physical activity is associated with RA. Suggestions for future researchers to focus more on treatments that can be done to reduce the risk of Rheumatoid Arthritis in elderly.
“…The results of a study conducted by Eledo et al [9] showed that positive Rheumatoid Arthritis occurred significantly in 5% of the population. The prevalence of this population is 4% in female subjects in the age range of 65-80 years and 1% in men in the age range of 61-70 years.…”
Section: Rheumatoid Arthritis In Elderly Womenmentioning
Rheumatoid Arthritis (RA) is an autoimmune disease that causes joint inflammation. Elderly, especially women are more susceptible to RA due to hormonal factors. RA patient often feel inconvenient during physical activity because of pain in their joint. The purpose of this study was to determine the effect of physical activity on elderly woman with Rheumatoid Arthritis. This research is a literature study using traditional review method. Journal article studies were searched in Google Scholar, OneSearch Indonesia, and Garuda in Bahasa and English language that published online from 2012-2022 according to keywords. Of 9.030 studies from databases identified 30 journal studies were included. Literature studies show that the prevalence of elderly women with RA is higher than men. These studies also shows that severity of RA affects the ability of elderly to do a physical activity and physical activity itself influences reducing pain and preventing the severity of RA. The conclusion of this study is that the prevalence of elderly women with RA is higher than men and physical activity is associated with RA. Suggestions for future researchers to focus more on treatments that can be done to reduce the risk of Rheumatoid Arthritis in elderly.
The presence or lack of antibodies is normally used for the classification of rheumatoid arthritis into a seropositive or seronegative condition. The inflammatory nature of rheumatoid arthritis often leads to permanent disability with approximately 60% of the affected individuals being unproductive at least, 10 years after the onset of the disease. 6 Osteoarthritis on the other hand is associated with cartilage breakdown, synovial membrane inflammation and restructuring of the hip and knee. It also affects the joints of the extremities and spine and manifest occasionally with stroke. 11 Therefore, understanding the pathogenic mechanism of the onset of polyarthritis will give insight into its management. The mechanism underlying oedema and polyarthritis involves transduction and reactions that modulate the expression of TNF-α, NF-κB, 3,12 cyclooxygenases, 13-14 pancreatic enzymes that upregulate subcutaneous fat necrosis and arthritis 1 and hepatocytes immune effector cells and cytokines. 15 Studies reveal polyarthritis disease was observed in some patients after inoculation with mRNA vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). [16][17][18] Complications and mortality arising from oedema and polyarthritis have increased the reliance on the use of corticosteroids, analgesics, non-steroidal anti-inflammatory drugs (NSAIDs), and diseasemodifying antirheumatic drugs in their treatment. Unfortunately, the therapeutic approaches of these treatment options, are often not achieved in clinical practice due to reduced levels of effective treatment compared with clinical trial results. 19 Additionally, these therapeutic approaches do not stop or reduce the progress of structural damage and are often associated with gastrointestinal and digestive disturbances. This has increased the need for the search of alternative management and treatment outcomes from dietary plant supplements. 11,13,20
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