The prevalence of primary open-angle glaucoma in Japanese

Iwase, Aiko; Suzuki, Yoshiyuki; Araie, Makoto; Yamamoto, Tetsuya; Abe, Haruki; Shirato, Shiroaki; Kuwayama, Yasuaki; Mishima, Hiromu K.; Shimizu, Hiroyuki; Tomita, Goji; Inoue, Yoshio; Kitazawa, Yoshiaki

doi:10.1016/j.ophtha.2004.03.029

Cited by 468 publications

(277 citation statements)

References 42 publications

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“…Progression ( prevalence of myopia and NTG are both high (Iwase et al 2004;Suzuki et al 2006;Sawada et al 2008). Although IOP is consistently a risk factor for the progression of POAG or progression from ocular hypertension to POAG (Gordon et al 2002;Heijl et al 2002;Bengtsson & Heijl 2005;Leske et al 2007), IOP is not always a strong risk factor for progression in NTG (Ishida et al 1998(Ishida et al , 2000Drance et al 2001;Tezel et al 2001).…”

Section: Discussionmentioning

confidence: 99%

“…In Japan, the prevalence of POAG was reported to be 3.9%, and 92% of POAG has been classified as NTG whose mean IOP was 15.2 mmHg (Iwase et al 2004;Kawase et al 2008). Extrapolating the results obtained in NTG eyes with IOP of 16-17 mmHg (Collaborative NormalTension Glaucoma Study Group 1998; Leske et al 2007), many of these patients are currently treated with ocular hypotensive eye drops.…”

Section: Risk Factors For Progression Of Normal-tension Glaucoma Undementioning

confidence: 99%

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Risk factors for progression of normal‐tension glaucoma under β‐blocker monotherapy

Araie

Shirato²,

Yamazaki

et al. 2012

Acta Ophthalmologica

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ABSTRACT.Purpose: To prospectively study prognostic factors for normal-tension glaucoma (NTG) under treatment with topical b-blocker. Methods: One hundred and forty-six eyes of 146 patients with NTG with a mean untreated intraocular pressure (IOP) of 14 mmHg, mild to moderate visual field damage and mean spherical equivalent refraction of )3.5 ()8.0 to +2.0) dioptre were randomized to topical nipradilol or timolol and followed for 3 years. The Humphrey full threshold 30-2 visual field test was performed every 6 months, and optic disc photographs were obtained every 12 months. Progression was defined as visual field progression, optic disc and ⁄ or peripapillary nerve fibre layer change, and factors relating to progression were evaluated using Cox proportional hazards models. Results: IOP decreased by 1.0 mmHg over the 3-year period, during which 35% showed progression according to the aforementioned criteria. Optic disc haemorrhage (hazard ratio [HR] 4.00, p < 0.001) and less extent of myopia (per dioptre, HR 1.15, p = 0.013) were significant risk factors. When progression was defined by visual field progression only, less extent of myopia was again a significant risk factor (HR 1.17, p = 0.038). Conclusion: Beside optic disc haemorrhage, less extent of myopia was a risk factor for progression in the current NTG population where most patients were mildly myopic and IOP during follow-up averaged 13.2 mmHg under topical b-blocker.

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Section: Discussionmentioning

confidence: 99%

Section: Risk Factors For Progression Of Normal-tension Glaucoma Undementioning

confidence: 99%

Risk factors for progression of normal‐tension glaucoma under β‐blocker monotherapy

Araie

Shirato²,

Yamazaki

et al. 2012

Acta Ophthalmologica

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“…The Japan Glaucoma Society conducted a population-based screening of glaucoma (the Tajimi Study) during 2000 and 2001. The prevalence of glaucoma in Japanese aged ≥ 40 years was estimated at 5.8% (3.9% with open-angle glaucoma, 1.1% with angle-closure glaucoma, and others), which is even higher than that of Caucasians [4]. As both OAB and glaucoma increase with age, many elderly will have both conditions.…”

Section: Discussionmentioning

confidence: 97%

“…Fink et al [8] reported that, even when radiologists understand the difference between open-angle and angleclosure glaucoma, nearly half still withhold buscopan in patients with a history of glaucoma, because of established teaching and fear of litigation. In the Tajimi Study [4], the prevalence of angle-closure glaucoma was rather high in the Japanese, especially in women, consistent with other reports that angle-closure glaucoma varies with race; angle-closure glaucoma occurs in 1 : 1000 Caucasians, in ª 1 : 100 Asians (especially Mongoloids) and Hispanics, and in 2-4 : 100 Inuits [5]. The incidence of drug-induced cases is uncertain [5], but the mydriatic effect of systemically administered anticholinergics is much smaller than that of dilating eye drops used for diagnostic purposes.…”

Section: Discussionmentioning

confidence: 99%

“…Although OAB and glaucoma are common, with an individual and coexistent prevalence higher in the elderly [3,4], the instructions provided with anticholinergics often state that the generalized term 'glaucoma' is a contraindication, without specifying the mechanism of drug-induced angle-closure glaucoma [5]. This statement is confusing to both clinicians and patients, and deprives many patients with OAB and a history of glaucoma of the most suitable drug treatment.…”

Section: Introductionmentioning

confidence: 99%

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Managing patients with an overactive bladder and glaucoma: a questionnaire survey of Japanese urologists on the use of anticholinergics

Kato¹,

Yoshida²,

Suzuki³

et al. 2004

BJU International

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prescribing anticholinergics, and 45 (29%) routinely referred patients with such a history to ophthalmologists. To treat patients with OAB and glaucoma, 102 (66%) would prescribe anticholinergics if permission were available from the ophthalmologist, 33 (21%) chose other treatments and 17 (11%) abandoned treatment. Forty-nine urologists (32%) were currently prescribing anticholinergics to patients with glaucoma.As to knowledge about glaucoma, 132 (85%) urologists knew that there were two types of glaucoma and 98 (63%) knew about laser iridotomy. The proportion of urologists who knew of the two types of glaucoma and asked patients for this information was significantly higher in university than in general hospitals ( P < 0.05). CONCLUSIONSAlthough anticholinergic drugs can precipitate angle-closure glaucoma by pupillary block, they are not contraindicated in open-angle glaucoma or in angle-closure glaucoma that has already been treated by laser iridotomy. Not all urologists are aware of this difference, at least in Japan. Some urologists avoid anticholinergics in all patients with glaucoma, while others pay little attention to glaucoma. Routine history taking and referral to ophthalmologists allows many patients with OAB and glaucoma to benefit safely from anticholinergics. Moreover, clinicians should be aware of patients with OAB who have not been evaluated by ophthalmologists but who are at risk of angle-closure glaucoma.

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Increase of Peak Intraocular Pressure During Sleep in Reproduced Diurnal Changes by Posture

Hara

Tsuru³

2006

Arch Ophthalmol

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Objective: To characterize diurnal intraocular pressure (IOP) changes in primary open-angle glaucoma by reproducing IOPs based on patient posture. Methods: In 148 patients with untreated primary openangle glaucoma who had IOPs recorded during clinic hours that were less than 21 mm Hg (average, 14.8±3.2 mm Hg), we measured IOP by noncontact tonometry every 2 hours from 6 AM to midnight and every 3 hours from midnight to 6 AM with patients sitting and supine. The IOP was reproduced by designating the sitting IOP as measurements taken when the patient was awake and the supine IOP as measurements taken when the patient was asleep for each individual. The reproduced diurnal IOP was composed of 12 measurements that included 2 to 4 IOP levels measured with the patients supine and the rest while they were sitting. Results: The peak of sitting diurnal IOP (mean±SD) for 148 patients was 16.0 ± 2.7 mm Hg, which was signifi

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The prevalence of primary open-angle glaucoma in Japanese

Cited by 468 publications

References 42 publications

Risk factors for progression of normal‐tension glaucoma under β‐blocker monotherapy

Risk factors for progression of normal‐tension glaucoma under β‐blocker monotherapy

Managing patients with an overactive bladder and glaucoma: a questionnaire survey of Japanese urologists on the use of anticholinergics

Increase of Peak Intraocular Pressure During Sleep in Reproduced Diurnal Changes by Posture

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