The prevalence of panic disorder in pregnant women during the third trimester of pregnancy

Güler, Özkan; Şahin, Figen Kır; Emül, H. Murat; Özbulut, Ömer; Geçici, Ömer; Uğuz, Faruk; Gezginç, Kazım; Zeytinci, Ismet Esra; Karatayli, Savas; Askin, Rustem

doi:10.1016/j.comppsych.2007.08.008

Cited by 32 publications

(15 citation statements)

References 22 publications

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“…Few studies have examined PD in OB/GYN clinics, particularly among pregnant patients and the detailed analyses of factors affecting POPD were not included. There is no uniformity worldwide for the observed prevalence of PD during pregnancy, which generally averages between 0.2% and 5.2% in multiple studies (10,11,12,29,30). One explanation for this diversity is that the screening and diagnostic instruments used in these studies vary in sensitivity.…”

Section: Discussionmentioning

confidence: 99%

“…We previously reported the current prevalence rate of PD as 2.5% (n=13) in 512 pregnant women during the third trimester of pregnancy (10). Of these 13 women who met the criteria for PD according to SCID-I, seven (1.3%) reported that their PD began during the 6 th -28 th weeks of their gestation.…”

Section: Discussionmentioning

confidence: 99%

“…Although a large group of women are likely to experience PD during their childbearing years, the incidence-prevalence and correlation of panic during the pregnancy period are not well defined. Limited data indicate that PD consequently affects approximately 1.5%-2.5% of pregnancies during pregnancy (10,11,12). Similarly, there are limited data on the comorbidity of PD, including Axis II disorders, during gestation.…”

Section: Introductionmentioning

confidence: 99%

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Pregnancy-Onset Panic Disorder: Incidence, Comorbidity and Associated Factors

Güler

Kaya

Gezginç

et al. 2015

Arch Neuropsychiatr

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Introduction: The present study aimed to investigate the incidence rate of pregnancy-onset panic disorder (POPD) among Turkish pregnant women using a diagnostic interview. Additionally, we examined whether the independent socio-demographic or clinical risk factors were associated with the risk of panic disorder in these women.Methods: The study sample comprised 1475 consecutive pregnant women who presented to the obstetric outpatient clinics of two research centers. The rate of POPD in these participants was 1.3% (Group 1, n=20). The 20 women with POPD were compared with 250 pregnant women without pregnancy-onset depression or anxiety (Group 2; controls). Panic disorder and other anxiety or mood disorders were determined by means of the Structured Clinical Interview for DSM-IV. Comorbid Axis II disorders were diagnosed with the Structured Clinical Interview for DSM-III-R Personality Disorders. Results:The incidence rate of panic disorder was 1.3% (n=20). In group 1, 55% (n=11) of the women with POPD had an additional mood or anxiety disorder. In addition, the prevalence rate of any cluster C personality disorder, including avoidant, passive-aggressive and obsessivecompulsive personality disorders, were significantly greater in the group 1 women with POPD than the control pregnant women without a panic disorder (group 2). Conclusion:The women with POPD were more likely than the controls to have a cluster C Axis II disorder and a history of a pre-existing anxiety or mood disorder.Keywords: Pregnancy, panic, comorbidity, personality ABSTRACTResearch Article

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Pregnancy-Onset Panic Disorder: Incidence, Comorbidity and Associated Factors

Güler

Kaya

Gezginç

et al. 2015

Arch Neuropsychiatr

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“…The peripartum period is also a high‐risk time for a woman to develop anxiety disorders, including post‐traumatic stress disorder (PTSD), panic disorder and obsessive‐compulsive disorder (OCD) (Ayers & Pickering, 2001; Forray, Focseneanu, Pittman, McDougle, & Epperson, 2010; Guler et al, 2008). Severe maternal anxiety during pregnancy can affect birth weight (Field et al, 2003), labor timing (Dayan et al, 2002) and fetal blood flow (Sjöström, Valentin, Thelin, & Marsál, 2002), and can contribute to long‐term behavioral and emotional problems in children (O'Connor et al, 2005).…”

Section: Implications Of Perinatal Mental Healthmentioning

confidence: 99%

Statewide Innovations to Improve Services for Women with Perinatal Depression

Shade¹,

Miller²,

Borst³

et al. 2011

Nursing for Women's Health

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“…[3] Indeed, literature underlines that between 3 and 16% of pregnant women fulfill the diagnostic criteria for unipolar major depression. [4,5] Of women with obsessive-compulsive disorder, 15-39% report the onset of their symptoms during pregnancy, [6][7][8] whereas data from a small study suggest that the prevalence of panic disorder during pregnancy may be as high as 2.5% [9] : in this specific condition, the worsening of panic symptoms is more frequent than their improvement. [10] Prenatal bipolar depression may affect nearly 50% of women with a history of bipolar disorder, [11,12] whereas evidence regarding both course and prevalence of generalized anxiety, personality, and schizophreniaspectrum disorders in this phase of the female reproductive cycle remains inconclusive.…”

Section: Introductionmentioning

confidence: 98%

Neurodevelopmental effects of prenatal exposure to psychotropic medications

Gentile¹

2010

Depress. Anxiety

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Until now, studies on the reproductive safety of psychotropics have typically assessed the risk of congenital malformations and perinatal complications associated with in utero exposure to such medications. However, little is known of their inherent potential neurobehavioral teratogenicity. The objective is to analyze available data from studies investigating developmental outcome of children exposed prenatally to psychotropics. A computerized Medline/PubMed/TOXNET/ENBASE search (1960-2010) was conducted using the following keywords: pregnancy, child/infant development/neurodevelopment, antidepressants, benzodiazepines, mood stabilizers, and antipsychotics. A separate search was also run to complete the safety profile of single specific medications. Resultant articles were cross-referenced for other relevant articles not identified in the initial search. A noncomputerized review of pertinent journals and textbooks was also performed. All studies published in English and reporting primary data on the developmental outcome of infants exposed in utero to psychotropics and born without malformations were collected. As regards antiepileptic drugs, only studies that provided data on specific medications approved for psychiatric practice use (carbamazepine, lamotrigine, and valproate) were considered. Data were extracted from 41 articles (38 identified electronically and 3 nonelectronically), which met the inclusion criteria. Despite reviewed studies showing relevant methodological limitations, concordant, albeit preliminary, information seems to exclude that prenatal exposure to both selective serotonin reuptake inhibitors and tricyclic antidepressants may interfere with the infants' psychological and cognitive development. Conversely, information on valproate strongly discourages its use in pregnant women. Moreover, although data on carbamazepine remain controversial, information on whole classes of drugs and single medications is either absent (second-generation antipsychotics) or too limited (first-generation antipsychotics, benzodiazepines, lithium, and lamotrigine) to inform the decision-making process. For all classes of psychotropics, new and/or further studies are warranted to answer definitively the urgent question about the impact of prenatal exposure to such medications on infant development.

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The prevalence of panic disorder in pregnant women during the third trimester of pregnancy

Cited by 32 publications

References 22 publications

Pregnancy-Onset Panic Disorder: Incidence, Comorbidity and Associated Factors

Pregnancy-Onset Panic Disorder: Incidence, Comorbidity and Associated Factors

Statewide Innovations to Improve Services for Women with Perinatal Depression

Neurodevelopmental effects of prenatal exposure to psychotropic medications

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