The prevalence of oilseed rape hypersensitivity in a mixed cereal farming population

Abstract

Oilseed rape does not cause significant allergy, even in areas of high production. It is likely that those patients exhibiting oilseed rape allergy may in fact be symptomatic due to the effect of other allergens, acting either synergistically with the oilseed rape allergen, or more likely, in spite of it.

Allergens and Toxins from Oleaginous Plants: Problems and Solutions

“…Knowing that the oilseed rape production is widespread in cereal growing areas and that many patients who attend the clinic (district general hospital, UK) for seasonal allergies claim that they are allergic to it, the aim of the work in development by Trinidade et al (2010) is to determine the prevalence of oilseed rape allergy in this population. They observed that oilseed rape hypersensitivity was relatively uncommon, comprising only 2% of the population tested (n = 28).…”

“…Oilseed rape does not cause significant allergy, even in areas of high production. It is likely that those patients exhibiting oilseed rape allergy may in fact be symptomatic due to the effect of other allergens, acting synergistically with the oilseed rape allergen (Trinidade et al, 2010).…”

Computational identification of Brassica napus pollen specific protein Bnm1 as an allergen

“…With the pace of the cultivation rate of this plant an alarming concern for allergenicity is generated, since pollen from oilseed rape have been reported as potential allergen. In the most abundant regions, most patients with hay-fever blame the blooming of Brassica napus for their symptoms during its flowering season [15]. During this flowering season the microscopic male cells of the plant make round or oval structural grain which is programmed to transport along the wind to help in the process of pollination.…”

“…During this flowering season the microscopic male cells of the plant make round or oval structural grain which is programmed to transport along the wind to help in the process of pollination. Pollens of Brassica napus guided by the wind are spreaded everywhere around the cultivated land and people mostly farmers having exposed to it suffer from hay-fever, allergic rhinitis like seasonal diseases [15] Although some of the high molecular mass proteins in oilseed rape pollen have been identified as allergens [16][17][18][19][20], a quest for other allergens is going on in different laboratories. In modern biology, in silico approaches have made it possible to give a straightforward time and money saving way to find out the solution of many biological problems like vaccine design [21], prediction of deleterious effects of mutations [22] and many more.…”