The prevalence of obstructive sleep apnoea syndrome in ankylosing spondylitis patients

Abstract

The prevalence of OSAS in AS patients is higher than reported in the general population. The diagnosis of OSAS should be kept in mind and OSAS symptoms should be considered especially in AS patients at the age of >or=35 years and in AS patients with a disease duration of >or=5 years.

http://www.archivesofrheumatology.org/abstract/745

“…9 The other study found an OSAS prevalence of 22.6% based on PSG examination in AS patients. 10 Considering that the OSAS prevalence is 2-7% in the normal population, 21 OSAS prevalence is substantially high in our study as well as in both of the other studies.…”

“…These findings suggest that OSAS prevalence increased in patients with advanced cervical vertebral disease (increased occiput-to-wall distance and neck thickness) causing oropharyngeal airway obstruction and tracheal compression. In fact, Solak et al 10 also found a greater occiput-to-wall distance and neck thickness in patients with OSAS even though their results could not reach statistical significance, most probably due to the limited sample size. This was overcome by a larger sample size in our study.…”

“…Studies employing PSG to determine sleep disturbance in AS have either been scarce or studied in limited numbers of patients. 9,10 Thus, in this study, we aimed to determine the prevalence of OSAS and assess sleep efficiency in patients with AS.…”

Prevalence and factors associated with disturbed sleep in patients with ankylosing spondylitis and non-radiographic axial spondyloarthritis: a systematic review

“…The method of collection of sleep data varied within the 15 studies as shown in Table 2 . Two studies included objective measurements of sleep: polysomnography (PSG), [ 21,35 ] and measurement of Apnoea-Hypopnoea Index (AHI) [ 35 ]. Both studies supplemented objective data with subjective data.…”

Lower Frequency of Obstructive Sleep Apnea in Spondyloarthritis Patients Taking TNF-Inhibitors

“…Two small uncontrolled studies reported OSA prevalences of 12% and 23% in ankylosing spondylitis (AS) patients, compared to 1% to 9% in the general population. 5,6 Psoriatic arthritis (PsA) has been associated with sleep interference independent of body mass index (BMI), 7 and a higher prevalence of OSA has been reported in psoriasis patients compared to controls. 8 Various mechanisms have been proposed to explain the high prevalence of OSA in SpA patients including (1) glucocorticoidinduced weight gain, (2) compression of the oropharyngeal airway by the cervical spine, and (3) systemic infl ammation.…”