The prevalence of newly diagnosed hyperlipidaemia in men with erectile dysfunction

Abstract

OBJECTIVETo determine the prevalence of newly diagnosed hypercholesterolaemia and hypertriglyceridaemia in patients presenting to an andrology clinic with erectile dysfunction (ED), and to assess the relationship between serum lipid levels and the severity of ED. PATIENTS AND METHODSIn all, 199 consecutive men attending an ED clinic were assessed for risk factors for ED; patients completed the International Index of Erectile Function (IIEF)-15 questionnaire and provided venous blood samples for assaying fasting total cholesterol and total triglyceride levels. The proportion of newly diagnosed hyperlipidaemia in patients presenting with ED was calculated and related to patient age, total IIEF score and severity of ED. RESULTSUsing a threshold of 5.0 mmol/L, there was newly diagnosed hypercholesterolaemia in 40% of the men, while there was undiagnosed hypertriglyceridaemia ( > 2 mmol/L) in 29% of the population. There was no clear correlation between patient age and the fasting lipid levels, and no association between total IIEF-15 score or severity of ED and serum cholesterol and triglyceride levels. CONCLUSIONThis study shows the high prevalence of undiagnosed hypercholesterolaemia and hypertriglyceridaemia in men presenting with ED. The opportunity to screen for and treat these risk factors has long-term benefits in preventing cardiovascular disease in this group of patients.

Asexuality Development among Middle Aged and Older Men

“…These inconsistent findings might originate from the difference of population. Smith et al [31] found that there was no association between total IIEF-15 score or severity of ED and serum cholesterol and triglyceride levels, and Hall et al [32] also found there was no significant positive association between untreated hyperlipidemia and ED in multivariate model. In our study population, most subjects had older age (64.5 percent >60 years) and suffered increasing systemic diseases, thus their poor health status would urge them to improve their lifestyles (for example, the improvement of diet and physical activity behaviors), which might benefit their control of dyslipidemia and obesity.…”

The Association Between Dyslipidemia and Its Treatment with Erectile Dysfunction

“…However, the study failed to highlight dyslipidemia as an independent risk factor [ 10 ]. On the contrary, Smith et al [ 11 ] reported a high prevalence of newly diagnosed hypercholesterolemia and hypertriglyceridemia in men attending an ED clinic. In a large cohort of 272,325 patients with ED, the prevalence of hyperlipidemia was 20.2 %, and the age-specifi c prevalence ranged from 3.9 to 52.3 % [ 12 ].…”

Assessment of endothelial function in the patient with erectile dysfunction: an opportunity for the urologist

“…Just how important the role of the urologist can be in helping discover cardiovascular disease was demonstrated by a study by Smith et al, 105 in which 40% of patients presenting with ED to the urologist's office were diagnosed with new dyslipidemia. Although the cardiovascular benefits of diagnosis and treatment of dyslipidemia are undoubted, one would not define the prescription of statin therapy as a core task for a urologist.…”