The prevalence of mixed DNA profiles on fingernail swabs

Dowlman, Edward A.; Martin, Nicola; Foy, Melanie J.; Lochner, Tobie; Neocleous, Tereza

doi:10.1016/j.scijus.2009.03.005

Cited by 31 publications

(24 citation statements)

References 9 publications

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“…This non-self DNA was possibly present on the hands prior to experiment commencement or alternatively picked-up during the experiment from the ''dirty'' objects/surfaces. This is supported by a number of studies which show that hands can contain non-self DNA [19][20][21][22][23][24][25][26]. An example of this was the multi-step transfer of DNA in experiment 1 where DNA from the chair arm was picked up by a participant's hand and transferred to other experimental surfaces.…”

Section: Discussionmentioning

confidence: 90%

The complexities of DNA transfer during a social setting

Goray

Oorschot

2015

Legal Medicine

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Section: Discussionmentioning

confidence: 90%

The complexities of DNA transfer during a social setting

Goray

Oorschot

2015

Legal Medicine

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“…perform more studies similar to those of Raymond et al [67], Cook and Dixon [202], Dowlman et al [203] and Toothman et al [201] in order to learn more about the occurrence and persistence of DNA on particular surfaces in different environmental conditions…”

Section: Contamination Issuesmentioning

confidence: 99%

Forensic trace DNA: a review

2010

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DNA analysis is frequently used to acquire information from biological material to aid enquiries associated with criminal offences, disaster victim identification and missing persons investigations. As the relevance and value of DNA profiling to forensic investigations has increased, so too has the desire to generate this information from smaller amounts of DNA. Trace DNA samples may be defined as any sample which falls below recommended thresholds at any stage of the analysis, from sample detection through to profile interpretation, and can not be defined by a precise picogram amount. Here we review aspects associated with the collection, DNA extraction, amplification, profiling and interpretation of trace DNA samples. Contamination and transfer issues are also briefly discussed within the context of trace DNA analysis. Whilst several methodological changes have facilitated profiling from trace samples in recent years it is also clear that many opportunities exist for further improvements.

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“…The presence of saliva on its own does not indicate cunnilingus occurred due to the potential of indirect transfer of the fluid. The same can be said for low‐level DNA transfer (<11 alleles), as sporadic alleles from background populations has been seen in other research and DNA transfer due to indirect transfer has been highlighted to take place .…”

Section: Resultsmentioning

confidence: 68%

Background Levels of Salivary‐α‐amylase Plus Foreign DNA in Cases of Oral Intercourse: a Female Perspective

Breathnach

Moore

2015

Journal of Forensic Sciences

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Saliva plus DNA from a suspect is commonly encountered in sexual assault cases on bodily swabs. However, without background knowledge, the weight of this evidence is unknown. It may indicate the presence of saliva resulting from cunnilingus, or it may represent indirect transfer. In this study, females who refrained from cunnilingus donated 43 items of underwear and 19 vaginal swabs. The samples were subjected to Phadebas(®) , RSID(™) -Saliva and mRNA profiling and were subsequently DNA-profiled to determine the prevalence of background saliva in the female population. The results report that 15.8% of females who refrained from cunnilingus were positive for saliva and a further 10.5% also had DNA from unknown source(s). These findings of the rate of indirect transfer were evaluated with the Bayesian approach, and it was found that the evidence of saliva plus a high foreign DNA source adds moderately strong support to the allegation of cunnilingus.

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The prevalence of mixed DNA profiles on fingernail swabs

Cited by 31 publications

References 9 publications

The complexities of DNA transfer during a social setting

The complexities of DNA transfer during a social setting

Forensic trace DNA: a review

Background Levels of Salivary‐α‐amylase Plus Foreign DNA in Cases of Oral Intercourse: a Female Perspective

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