The prevalence of macrovascular disease and lipid abnormalities amongst diabetic patients in Sri Lanka

Fernando, D. J. S.; Siribaddana, Sisira; Perera, Nilanka; Perera, S.; Silva, Dulmini Kavindya De

doi:10.1136/pgmj.69.813.557

Cited by 14 publications

(10 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Gender and past history were significant predictors of CAD. These findings are consistence with findings of other studies done in Sri Lanka and in the region [13,14,15,16,17].…”

Section: Papersupporting

confidence: 77%

“…In this study significantly higher prevalence of ECG coronary possible (on Minnesota coding) was detected in the study group compared to the age and sex matched control group [16]. Prevalence of CAD was assessed using the London School of Hygiene questionnaire and 12 lead ECG to diagnose definitive CAD (positive symptoms and ECG), evidence of CAD (history alone) and silent ischaemia (positive ECG without symptoms).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Prevalence of coronary artery disease in a semi urban population in Southern Sri Lanka

Jayawardene

Samarutilake²,

Zackie

et al. 2017

Ceylon Med. J.

View full text Add to dashboard Cite

Introduction Prevalence of coronary artery disease (CAD) is on the rise in Sri Lanka resulting in high hospital mortality rates. Because of paucity of community based data on CAD we carried out this study to assess prevalence of CAD and associated factors in a suburban population in Southern Sri Lanka.Methods A cross sectional descriptive study was carried out among community living adults aged 30 years or more in Bope-Poddala Medical Officer of Health (MOH) area. Total of 1000 eligible individuals were recruited using cluster sampling. Cardiovascular Questionnaire of London School of Hygiene was administered to each participant by trained data collectors. CAD was diagnosed using criteria by Epstein and colleagues and electrocardiograms were classified according to the Minnesota code by a Cardiologist blinded to participant details [9,10].Results Total of 579 (57.9%) females and 421 (42.1%) males were studied. Mean age of the group was 53 years. Among the participants 32% had cardiovascular risk related non communicable diseases (NCDs) and 22.2% had a family history of the same. Prevalence of CAD was 6.9% (95% CI: 5.33 -0.47) and silent ischaemia was 2.2% (95% CI: 1.29 -3.11). Only gender and past history of cardiovascular risk related NCDs emerged as predictors of CAD.Conclusion CAD was more prevalent among males and those with past history of cardiovascular risk related NCDs. Community based preventive programmes should be implemented to minimize the adverse impact of CAD.

show abstract

“…Gender and past history were significant predictors of CAD. These findings are consistence with findings of other studies done in Sri Lanka and in the region [13,14,15,16,17].…”

Section: Papersupporting

confidence: 77%

Section: Introductionmentioning

confidence: 99%

Prevalence of coronary artery disease in a semi urban population in Southern Sri Lanka

Jayawardene

Samarutilake²,

Zackie

et al. 2017

Ceylon Med. J.

View full text Add to dashboard Cite

show abstract

“…This estimation is relatively high when compared to the values obtained in a previous study done in 1993 (10). The high prevalence of myocardial ischaemia could be explained by the characteristics of the sample.…”

Section: Discussionmentioning

confidence: 62%

Prevalence of myocardial ischaemia among diabetics determined by validated Sinhala version of the WHO Rose angina questionnaire

Liyanage

Sathananthan

2013

Galle Med J

View full text Add to dashboard Cite

Objectives:Design Setting: Results:Interpretation:The aim of this study was to validate the original version of the Rose Angina Questionnaire (RAQ) and apply it to a group of long standing diabetics in a cross-sectional manner to assess it applicability in clinical settings.After a face validation and piloting the Part A of the Sinhala translated RAQ (SRAQ-Part A) was given to 47 adult patients who presented with chest pain where the possibility of stable angina was considered in the differential diagnosis. In these patients, the diagnosis of stable angina was confirmed by resting ECG. Patients who had a normal resting ECG or changes non-confirmatory of myocardial ischaemia underwent treadmill examination to detect exercise-induced myocardial ischaemia.Part B of the translated RAQ (SRAQ-Part B) was given to 68 patients who presented with acute chest pain of less than 24 hours where acute coronary syndrome was considered a possibility. These patients underwent serial ECGs and cardiac enzymes/troponin estimations.The validated SRAQ were administered to a group of diabetics (n = 311) attending medical clinics of Teaching hospital, Karapitiya in a cross-sectional manner to detect the prevalence of stable angina or history of acute coronary syndrome. Sensitivity, specificity, positive predictive value, and negative predictive values of SRAQ-Part A were 86.4%, 76%,76%, 86% and of part-B were 74.1, 70%, 93.5%, 31.8%, respectively.Of 311 diabetic patients the prevalence of stable angina in this group of patients would be 31% (95% CI = 26-37%). Part B of the questionnaire, 17 answered positively and rest negatively. Of these 17 positives, 16 were likely to have acute coronary disease.Our analysis shows that the Sinhala translation of the RAQ has an acceptable specificity and sensitivity in detecting either stable angina or acute coronary syndrome. The prevalence of stable angina was 31% among the diabetics selected for this analysis.

show abstract

“…162,163 By contrast, there have been no large populationbased studies specifically describing the prevalence of PAD in BMEGs. Retrospective hospital-based series from developing countries suggest that the overall prevalence of PAD may be lower than that seen in Western series [163][164][165][166][167][168] (Supplementary Table W4). By contrast, data from developed countries, notably the USA, suggest that non-white Europeans may at risk of accelerated atherosclerosis and lower limb ischaemia.…”

Section: Secondary Preventionmentioning

confidence: 99%

Ethnicity and cardiovascular disease prevention in the United Kingdom: a practical approach to management

et al. 2007

View full text Add to dashboard Cite

The United Kingdom is a diverse society with 7.9% of the population from black and minority ethnic groups (BMEGs). The causes of the excess cardiovascular disease (CVD) and stroke morbidity and mortality in BMEGs are incompletely understood though socio-economic factors are important. However, the role of classical cardiovascular (CV) risk factors is clearly important despite the patterns of these risk factors varying significantly by ethnic group. Despite the major burden of CVD and stroke among BMEGs in the UK, the majority of the evidence on the management of such conditions has been based on predominantly white European populations. Moreover, the CV epidemiology of African Americans does not represent well the morbidity and mortality experience seen in black Africans and black Caribbeans, both in Britain and in their native African countries. In particular, atherosclerotic disease and coronary heart disease are still relatively rare in the latter groups. This is unlike the South Asian diaspora, who have prevalence rates of CVD in epidemic proportions both in the diaspora and on the subcontinent. As the BMEGs have been under-represented in research, a multitude of guidelines exists for the 'general population.' However, specific reference and recommendation on primary and secondary prevention guidelines in relation to ethnic groups is extremely limited. This document provides an overview of ethnicity and CVD in the United Kingdom, with management recommendations based on a roundtable discussion of a multidisciplinary ethnicity and CVD consensus group, all of whom have an academic interest and clinical practice in a multiethnic community.

show abstract

The prevalence of macrovascular disease and lipid abnormalities amongst diabetic patients in Sri Lanka

Abstract: Hyperlipidaemia and macrovascular disease is common in non-insulin-dependent diabetic patients in Sri Lanka and accounts for significant morbidity.

Cited by 14 publications

References 15 publications

Prevalence of coronary artery disease in a semi urban population in Southern Sri Lanka

Prevalence of coronary artery disease in a semi urban population in Southern Sri Lanka

Prevalence of myocardial ischaemia among diabetics determined by validated Sinhala version of the WHO Rose angina questionnaire

Ethnicity and cardiovascular disease prevention in the United Kingdom: a practical approach to management

Contact Info

Product

Resources

About