The prevalence of hypertension in relation with the normal albuminuria range in type 2 diabetes mellitus within the South Korean population: The Korean National Health and Nutrition Examination Survey, 2011–2012

Shin, Koh Eun; Roh, Yong Kyun; Cho, Kyung-Hwan; Han, Kyung Do; Park, Yong Gyu; Kim, Do-Hoon; Kim, Yang Hyun

doi:10.1016/j.pcd.2017.02.007

Cited by 3 publications

(2 citation statements)

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“…The most significant contributing factor in the pathogenesis and the progression of abnormal ACR is elevated blood pressure, which eventually leads to the development of diabetic nephropathy in both Type 1 and Type 2 diabetic patients [44,45]. In the present study microalbuminuric had significantly higher SBP (p=0.03) and DBP (p=0.02) than normoalbuminuric subjects which is consistent with findings from other studies [32,46,47]. Microalbuminuric patients tend to have higher DM, family history of DM, family history of HTN, but no independent significant association was observed in the present study although in most of the studies a good association has been observed [48].…”

Section: Discussionsupporting

confidence: 92%

Determination of Microalbuminuraia and Its Relation to HTN in Type 2 Diabetic Patients and General People

Monir¹,

Zeba²,

Sultana³

et al. 2019

EJPM

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Background: Microalbuminuria is a clinical marker of glomerular injury and identified as a risk of progressive renal damage, cardiovascular disease and morbidity. Hypertension (HTN) is a worldwide public health problem andcommonly coexists with Diabetes Mellitus (DM). Objective: The aim of the study was todetermine the prevalence of microalbuminuriain type 2diabetic patients and general people and the relationship between microalbuminuria withHTN and other clinical parametersin these twogroups of people. Methodology: A cross-sectional study was carried out using a pretested structured questionnaire amongrandomly selected107 participants aged from 35-70 years. Out of 107 participants 64 persons were type 2 diabetic patients and 43 were healthy individuals. Biochemical analysis of blood and urine samples was performed. Result: The prevalence of microalbuminuria was 17.2% in diabetic patients and 25.6% ingeneral people whereas the prevalence of HTN was 48.4% among diabetic patients and 51.6% in normal healthy persons. Regardless of the group considered, when microalbuminuria was analyzed according to the different clinical parameters, microalbuminuricpatients had significantly highersystolic (p=0.03) diastolic (p=0.02) blood pressure, urine creatinine (p=0.000), serum creatinine (p=0.012), urine albumin (p=0.019) and GFR (p=0.000). Microalbuminuria was found to be associated with HTN (odds ratio [OR] 3.5, 95% confidence interval [CI] 1.2-9.7). Conclusion: The study concluded thatmicroalbuminuria prevalence is high among general people and HTN has a significant relationship with microalbuminuria. These findings suggest early screening of microalbuminuria and the proper management of other clinical parameters to halt and prevent end stage renal disease and cardiovascular risk in future.

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Section: Discussionsupporting

confidence: 92%

Determination of Microalbuminuraia and Its Relation to HTN in Type 2 Diabetic Patients and General People

Monir¹,

Zeba²,

Sultana³

et al. 2019

EJPM

View full text Add to dashboard Cite

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“…And vitamin D analog also exhibited the inhibitory effect on inflammatory response in human thyroid cells and T cells [88]. ATD treatment caused a greater decline in TRAb in GD patients with normal vitamin D levels compared to that in GD patients with decreased vitamin D levels [89]. Moreover, a decreased baseline vitamin D level was associated with greater thyroid goiter in female patients with newly onset GD [90].…”

Section: Influencing Factors For the Recurrence In Gd Patientsmentioning

confidence: 99%

Antithyroid Drug Therapy for Graves’ Disease and Implications for Recurrence

Liu

et al. 2017

International Journal of Endocrinology

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Graves' disease (GD) is the most common cause of hyperthyroidism worldwide. Current therapeutic options for GD include antithyroid drugs (ATD), radioactive iodine, and thyroidectomy. ATD treatment is generally well accepted by patients and clinicians due to some advantages including normalizing thyroid function in a short time, hardly causing hypothyroidism, and ameliorating immune disorder while avoiding radiation exposure and invasive procedures. However, the relatively high recurrence rate is a major concern for ATD treatment, which is associated with multiple influencing factors like clinical characteristics, treatment strategies, and genetic and environmental factors. Of these influencing factors, some are modifiable but some are nonmodifiable. The recurrence risk can be reduced by adjusting the modifiable factors as much as possible. The titration regimen for 12–18 months is the optimal strategy of ATD. Levothyroxine administration after successful ATD treatment was not recommended. The addition of immunosuppressive drugs might be helpful to decrease the recurrence rate of GD patients after ATD withdrawal, whereas further studies are needed to address the safety and efficacy. This paper reviewed the current knowledge of ATD treatment and mainly focused on influencing factors for recurrence in GD patients with ATD treatment.

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The independent and interactive effects of phthalates exposure and hypertension on the indicators of early renal injury in US adults: Evidence from NHANES 2001–2004

Liu

Yang²,

Yang³

et al. 2022

Environmental Research

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The prevalence of hypertension in relation with the normal albuminuria range in type 2 diabetes mellitus within the South Korean population: The Korean National Health and Nutrition Examination Survey, 2011–2012

Cited by 3 publications

References 45 publications

Determination of Microalbuminuraia and Its Relation to HTN in Type 2 Diabetic Patients and General People

Determination of Microalbuminuraia and Its Relation to HTN in Type 2 Diabetic Patients and General People

Antithyroid Drug Therapy for Graves’ Disease and Implications for Recurrence

The independent and interactive effects of phthalates exposure and hypertension on the indicators of early renal injury in US adults: Evidence from NHANES 2001–2004

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