The prevalence of hypertension and diabetes defined by fasting and 2‐h plasma glucose criteria in urban Nepal

Shrestha, Umid Kumar; Singh, Dipendra Raman; Bhattarai, Madhur Dev

doi:10.1111/j.1464-5491.2006.01953.x

Cited by 80 publications

(77 citation statements)

References 12 publications

(18 reference statements)

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“…Diabetes prevalence in Nepal has increased over the past three decades [16]; and there appear to be a significant number of undiagnosed cases [17]. Effective diabetes management in Nepal, including diagnosis and treatment, is challenged by multiple factors, including poor overall understanding of diabetes in the community [18], limited healthcare resources, and substandard diagnostic and laboratory facilities [19,20].…”

Section: Introductionmentioning

confidence: 99%

Blood glucose monitoring in type 2 diabetes – Nepalese patients’ opinions and experiences

Sapkota

Brien

Aslani

2017

Global Health Action

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Background: Blood glucose monitoring forms a vital component of diabetes care. Monitoring conducted at home using glucometers, and in laboratories by professionals, are two common methods of blood glucose monitoring in clinical practice. Objective: To investigate Nepalese patients’ perceptions and practices of blood glucose monitoring in diabetes. Methods: In-depth interviews were conducted with 48 Nepalese participants with type 2 diabetes in Sydney and Kathmandu. The interviews were audio-recorded, transcribed verbatim and thematically analysed. Results: In Australia, most participants perceived home monitoring as useful; and both home and laboratory monitoring were conducted at fairly regular intervals. In Nepal, only a small number conducted home monitoring and the laboratory method formed the primary method of day-to-day monitoring. The laboratory method was preferred due to easy access to laboratories, lack of faith in glucometers and perceptions that home monitoring is costlier. However, overall monitoring was irregular in Nepal. In addition to the healthcare system which enabled cheaper self-monitoring in Australia, Nepalese in Australia also tended to have a better understanding about the purpose of home monitoring. Conclusions: This study has highlighted the disparity in perceptions and practices related to blood glucose monitoring. Understanding the importance of blood glucose monitoring and access to affordable resources are critical facilitators for conducting regular monitoring. Both patient and health-system factors play a key role in ensuring continued diabetes monitoring and management.

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Section: Introductionmentioning

confidence: 99%

Blood glucose monitoring in type 2 diabetes – Nepalese patients’ opinions and experiences

Sapkota

Brien

Aslani

2017

Global Health Action

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“…[13] The prevalence of pre-diabetes in this study is lower than 39.1% reported in Calabar, Nigeria [28] and 43% reported in Nepal. [18] However, the prevalence of pre-diabetes of 33.1% in this study is within the range of 25.0% -47.0% reported in the European Study of Hypertension and Diabetes. [29] However, this study has demonstrated the existence of pre-diabetes in essential hypertension which is an issue of phenomenal clinical and public health importance in Nigeria.…”

Section: Discussionmentioning

confidence: 71%

“…[7,28] and other parts of the world such as Nepal. [18] Although, the exact physiological mechanism linking pre-diabetes with essential hypertension are not known, but available evidence suggest that both conditions are related through insulin resistance in glucose metabolism and hyperinsulinaemia. [6,29] This is also explained in the constellation of abnormalities linking type 2 diabetes mellitus, hypertension and others constellations of metabolic syndrome.…”

Section: Discussionmentioning

confidence: 99%

“…[13] Shuqian et al, [17] in a study on the prevalence of diabetes mellitus and IFG in Chinese adults found an IFG prevalence of 4.9%. Shrestha et al, [18] reported a prevalence of 43% among hypertensive patients in urban Nepal. In Nigeria, a prevalence of 25% was reported among hypertensive patients in a teaching hospital in Enugu, Nigeria.…”

Section: Introductionmentioning

confidence: 99%

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Magnitude of Pre-Diabetes among Adult Nigerians with Essential Hypertension in a Primary Care Clinic of a Tertiary Hospital in South-Eastern, Nigeria

Iloh¹,

Uchenna²

2014

EJPM

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Abstract:Background: Hypertension co-existing with Diabetes mellitus is increasing globally. However, current evidence has demonstrated the existence of a prolonged, intermediate phase of diabetes termed pre-diabetes in hypertensive patients. Aim: This study was designed to determine the magnitude of pre-diabetes among adult Nigerians with essential hypertension in a primary care clinic of a tertiary hospital in South-eastern, Nigeria. Materials and Methods: A crosssectional analytic study carried out on 320 adult hypertensive Nigerians who were age and sex matched with 320 nonhypertensive, non-diabetic control group at the primary care clinic of a tertiary hospital in South-eastern Nigeria. These patients were screened for pre-diabetes. Pre-diabetes was defined as fasting plasma glucose of 100-125 mg/dL and /or plasma glucose level of 140-199 mg/dL two hours after a 75g oral glucose load. Hypertension was defined as systolic and/or diastolic blood pressures ≥140/90 mmHg or documented use of antihypertensive medications in a previously diagnosed person with hypertension. Results: The prevalence of pre-diabetes was significantly higher in hypertensive patients (33.1%) than control (16.2%) (p= 0.001) with impaired fasting glycaemia ((29.4%) being the more common pattern. The mean fasting plasma glucose of the hypertensive patients (122.4mg/dL±1.7)) was significantly higher than that of the control (91.8mg/dL±2.4) (p=0.000). Similarly, the mean two hours oral glucose load of the hypertensive patients (183.4mg/dL±1.6) was significantly higher than that of the control (161.8mg/dL±1.9)(p=0.001). Conclusion: This study has shown the existence of pre-diabetes among the hypertensive patients with impaired fasting glycaemia being the more common pattern. Screening adult Nigerians with essential hypertension for pre-diabetes should constitute clinical targets for intervention in primary care clinic.

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“…A study shows that the prevalence of diabetes and impaired fasti ng glycemia in Urban Nepal are higher than that of rural Nepal 5 . Diabetes mellitus is potent risk factors for CAD, but impaired glucose tolerance is coming up indicators for CAD 6 . This study was designed to correlate blood glucose level in the pati ents with coronary artery disease with acute coronary syndrome and to determine the relati onship of other risk factors.…”

Section: Introductionmentioning

confidence: 99%

Blood Glucose Levels in Patients with Coronary Artery Disease

Rajbhandari

Pandeya

Bhattarai

et al. 2013

Med. J. Shree Birendra Hosp.

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Introducti on: Diabetes Mellitus is a potent risk factor for Coronary Artery Diseases, but Impaired Glucose Tolerance is increasingly known risk factor for Coronary Artery Diseases. The aim of this study was to correlate blood glucose level in the pati ents with Coronary Artery Diseases with Acute Coronary Syndrome and to determine the relati onship of other risk factors.Methods: This was a cross-secti onal prospecti ve study of consecuti ve pati ents admitt ed in coronary care unit of Bir Hospital and Shaid Gangalal Nati onal Heart Center, with diagnosis of Acute Coronary Syndrome.Results: Total 209 pati ents were enrolled. 90.9% (190) had dyslipidemia, 78.5% were smokers with mean Standard Deviati on of durati on of smoking were 25.35 years. Abnormal waist to hip rati o in male and female are 56.3% and 76.1% respecti vely. 14.4 % (30) had Random Blood Glucose > 200mg%, 17.2 % had Impaired Fasti ng Glucose (110-126 mg% World Health Organizati on); 34.4% had Impaired Fasti ng Glucose (100-126 mg% American Diabeti c Associati on) 28.2% had Impaired Glucose Tolerance (postprandial blood glucose 140-200mg %).19.1% were old diabetes, 21.3% had recent diabetes mellitus, 52.7% had impaired glycemia.93.1% of total pati ents had Glucose Intolerance of any form.Conclusions: Almost all pati ents had diabeti c or glucose intolerance of any form prior to coronary artery disease with acute coronary syndrome. This study consisted with Asian criteria of body mass index and Waist circumference for overweight or obesity.

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The prevalence of hypertension and diabetes defined by fasting and 2‐h plasma glucose criteria in urban Nepal

Abstract: Our study shows that diabetes and hypertension are common and related problems in people aged >/= 40 years in urban Nepal. The overall sensitivity of the 2-h PG criteria was greater than that of the FPG criteria for diagnosing diabetes, except in subjects aged >/= 60 years.

Cited by 80 publications

References 12 publications

Blood glucose monitoring in type 2 diabetes – Nepalese patients’ opinions and experiences

Blood glucose monitoring in type 2 diabetes – Nepalese patients’ opinions and experiences

Magnitude of Pre-Diabetes among Adult Nigerians with Essential Hypertension in a Primary Care Clinic of a Tertiary Hospital in South-Eastern, Nigeria

Blood Glucose Levels in Patients with Coronary Artery Disease

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