The prevalence of hepatitis B and C infections among immigrants to a newly reclaimed area endemic for Schistosoma mansoni in Sinai, Egypt

Association between Schistosomiasis mansoni and hepatitis C: systematic review

“…6,9,29,36,37,39,40 Six studies made appropriate epidemiologic and statistical analyses to confi rm the correlation between risk factors associated and HCV infection in SM patients. 19,29,32,36,37,40 The other articles suggested possible risk factors without any statistical correlation found (Table 3). …”

“…2,9,19,29,30 Among the 13 articles included in the fi nal step of the review, ten were cross-sectional studies, 8,9,19,29,30,36,37,39,40,45 one was a retrospective cases series, 6 one was a prospective cases series 2 and the other was a cases series with an external control group. 32 Five studies 6,32,39,40,45 were conducted in Brazil, fi ve in Egypt, 2,9,19,29,30 two in Sudan, 36,37 one in Ethiopia 8 and one in Kenya. 9 A higher prevalence of HCV infection was found in the SM population of Egypt, compared to the other countries (Table 1).…”

“…Eight studies 2,6,19,32,36,37,40,45 sought to determine the serologic prevalence of HCV infection in an SM population and one study proposed to verify any epidemiologic relationship of schistosomiasis and HBV and HCV serologic markers. 30 Six studies 6,9,29,37,39,40 aimed to evaluate the severity of hepatic lesions and morbidity of hepatitis C when associated with SM and to correlate this with serologic markers.…”

“…Six studies did not mention the exclusion criteria adopted. 2,9,19,30,32,36 The most commonly chosen technique of HCV diagnosis was 3 rd generation anti-HCV ELISA, utilized in fi ve studies. 8,9,36,37,45 Four other studies utilized 2 nd generation anti-HCV ELISA.…”

“…8,9,36,37,45 Four other studies utilized 2 nd generation anti-HCV ELISA. 2,19,29,30 The quantifi cation of the viral titers was performed by HCV RNA PCR in seven studies. 6,9,29,36,37,39,40 Six studies made appropriate epidemiologic and statistical analyses to confi rm the correlation between risk factors associated and HCV infection in SM patients.…”