The prevalence of frozen shoulder in patients with limited Dupuytren disease

Abstract

Evidence from the literature suggests an association between Dupuytren disease and frozen shoulder syndrome, both clinically and histologically. An increased tendency for fibrotic healing after repetitive microtrauma could be an underlying mechanism. However, it remains unclear how strong this associa- tion is and if only mild signs of Dupuytren disease would also increase the risk of frozen shoulder. In 61 patients, we examined the hands for signs of Dupuytren disease and the shoulders for pain and limited motion. We found a 21,7% prevalence of frozen shoulder syndrome in patients with signs of Dupuytren disease versus 13,9% in those without. The other way around, in patients with frozen shoulder syndrome the prevalence of Dupuytren disease was 50% versus 36.7% in those without frozen shoulder syndrome. These differences were not statistically significant, contrary to similar research in the literature. However, methodological issues, especially the choice of control group, may explain the differences between our findings and previous studies. We conclude that the clinical association between Dupuytren disease may not be so strong as previously thought, especially in patients with only limited signs of the disease.

Exploring the potential relationship between frozen shoulder and Dupuytren’s disease through bioinformatics analysis and machine learning

“…The prevalence of DD ranges from 3% to 42% worldwide ( 11 ). DD is a common benign fibroproliferative condition ( 12 ). A fibrotic nodule over the palmar fascia is the most common symptom of the disorder.…”

“…Therefore, studying the pathogenesis is helpful and necessary for the development of disease treatments. Increasing evidence shows not only that there are some similar pathological features between DD and FS but also that there is a strong clinical correlation between them ( 12 , 15 ). There may be a breakthrough in understanding the pathogenesis of these two diseases due to their similarity.…”

“…DD is one of the most widespread inherited connective tissue disorders and appears to be common in northern Europeans (10). The prevalence of DD ranges from 3% to 42% worldwide (11). DD is a common benign fibroproliferative condition (12).…”