The prevalence of frailty syndrome in an older population from Spain. The Toledo study for healthy aging

García‐García, Francisco José; Ávila, Gonzalo Gutiérrez; Alfaro‐Acha, Ana; Andrés, María Solange Amor; Lanza, M. De Los Angeles de la Torre; Aparicio, M. V. Escribano; Aparicio, S. Humanes; Zugasti, José Luis Larrión; Reus, M. Gomez-Serranillo; Rodríguez‐Artalejo, Fernando; Rodríguez‐Mañas, Leocadio

doi:10.1007/s12603-011-0075-8

Cited by 244 publications

(203 citation statements)

References 30 publications

(41 reference statements)

Supporting

Mentioning

169

Contrasting

Unclassified

Order By: Relevance

“…This impairment in cognition is more severe in frail subjects over time than in non-frail subjects (Buchman et al 2007;McGough et al 2011;Samper-Ternentet al 2008). Additionally, poor physical outcomes, such as reduced gait velocity and muscle weakness, are associated with cognitive impairment (Samper-Ternent et al 2008), and these outcomes are physical domains of frailty (Garcia-Garcia et al 2011). In the present study, we aimed to investigate the possible differences in dual-task costs (i.e., decreases in performance when elderly participants switch from a single to a dual task) (Montero-Odasso et al 2012) between four groups differentiated by frailty status and cognitive impairment level.…”

Section: Discussionmentioning

confidence: 97%

“…One of the major negative consequences of dementia is a severe decline in physical activity, which can be attributed to several causes, including the use of physical restraints to prevent falls (Berzlanovich et al 2012;Gulpers et al 2010). Cognitive impairment and dementia have been closely related to frailty because these diseases share some of the same pathophysiological mechanisms, phenotypes, and short-and mid-term consequences (e.g., hospitalization, an increased incidence of falls, disability, institutionalization, and death) (Garcia-Garcia et al 2011;Hantikainen 1998;Roberston et al 2013).…”

Section: Introductionmentioning

confidence: 99%

“…A sensitive method for detecting these early interactions is the measurement of the effect that cognitive load has on gait (e.g., during simultaneous talking or counting while walking). It has been demonstrated that the inability to maintain a conversation while walking (i.e., Bstopping walking while talking^) is a marker of future falls in older adults (Lundin-Olsson et al 1997;Uemura et al 2012); therefore, walking while performing a secondary task (the dual-task paradigm) has become the classic method of assessing the interaction between cognition and gait (Casas-Herrero et al 2013;Doi et al 2012;Garcia-Garcia et al 2011;Makizako et al 2012;Maquet et al 2010;MonteroOdasso et al 2012). Dual-task tests reflect executive function, which is an essential cognitive resource for normal walking.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Do frailty and cognitive impairment affect dual-task cost during walking in the oldest old institutionalized patients?

Cadore

Casas‐Herrero

Zambom-Ferraresi

et al. 2015

AGE

View full text Add to dashboard Cite

The objective of this study was to investigate dual-task costs in several elderly populations, including robust oldest old, frail oldest old with MCI, frail oldest old without MCI, and frail elderly with dementia. Sixtyfour elderly men and women categorized into frail without MCI (age 93.4±3.2 years, n=20), frail with MCI (age 92.4±4.2 years, n=13), robust (age 88.2±4.1 years, n=10), and patients with dementia (age 88.1±5.1 years, n=21). Five-meter gait ability and timed-up-and-go (TUG) tests with single and dual-task performance were assessed in the groups. Dual-task cost in both 5-m habitual gait velocity test and TUG test was calculated by the time differences between single and dual-task performance. The robust group exhibited better 5-m gait and TUG test performances in the single and dual-task conditions compared with the other three groups (P < 0.001), and the frail and frail + MCI groups exhibited better performances than the dementia group (P<0.001). No significant differences were observed between the frail and frail + MCI groups. However, all groups exhibited lower gait velocities in the verbal and arithmetic task conditions, but the dual-task cost of the groups were similar. Robust individuals exhibited superior single and dual-task walking performances than the other three groups, and the frail and frail + MCI individuals exhibited performances that were superior to those of the patients with dementia. However, the dual-task costs, i.e., the changes in gait performance when elderly participants switch from a single to a dual task, were similar among all four of the investigated groups. Therefore, these results demonstrated that the magnitude of the impairment in gait pattern is independent of frailty and cognitive impairment status.

show abstract

Section: Discussionmentioning

confidence: 97%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Do frailty and cognitive impairment affect dual-task cost during walking in the oldest old institutionalized patients?

Cadore

Casas‐Herrero

Zambom-Ferraresi

et al. 2015

AGE

View full text Add to dashboard Cite

show abstract

“…Along with sarcopenia, skeletal muscle fat infiltration, which is assessed through muscle tissue attenuation, is associated with an increased risk of mobility loss in older men and women (Visser et al 2005). As a consequence of impaired muscle function, the diagnosis of frailty includes physical impairments, such as low gait speed, fatigue, and low grip strength (Fried et al 2001;Bandeen-Roche et al 2006;Garcia-Garcia et al 2011;Cameron et al 2013). Due to the physical domains that are related to frailty, physical activity is one of the most important components in the prevention and treatment of this syndrome.…”

Section: Introductionmentioning

confidence: 99%

Multicomponent exercises including muscle power training enhance muscle mass, power output, and functional outcomes in institutionalized frail nonagenarians

Cadore

Casas‐Herrero

Zambom-Ferraresi

et al. 2013

AGE

402

430

View full text Add to dashboard Cite

This randomized controlled trial examined the effects of multicomponent training on muscle power output, muscle mass, and muscle tissue attenuation; the risk of falls; and functional outcomes in frail nonagenarians. Twenty-four elderly (91.9±4.1 years old) were randomized into intervention or control group. The intervention group performed a twice-weekly, 12-week multicomponent exercise program composed of muscle power training (8-10 repetitions, 40-60 % of the one-repetition maximum) combined with balance and gait retraining. Strength and power tests were performed on the upper and lower limbs. Gait velocity was assessed using the 5-m habitual gait and the timeup-and-go (TUG) tests with and without dual-task performance. Balance was assessed using the FICSIT-4 tests. The ability to rise from a chair test was assessed, and data on the incidence and risk of falls were assessed using questionnaires. Functional status was assessed before measurements with the Barthel Index. Midthigh lower extremity muscle mass and muscle fat infiltration were assessed using computed tomography. The intervention group showed significantly improved TUG with single and dual tasks, rise from a chair and balance performance (P<0.01), and a reduced incidence of falls. In addition, the intervention group showed enhanced muscle power and strength (P<0.01). Moreover, there were significant increases in the total and high-density muscle cross-sectional area in the intervention group. The control group significantly reduced strength and functional outcomes. Routine multicomponent exercise intervention should be prescribed to nonagenarians because overall physical outcomes are improved in this population.

show abstract

“…It is estimated that by 2025, 1.2 billion people worldwide will be over 60 years old (1), with similar prevalence in Europe (2). In France, men and women aged 50 years old can expect to live free of disability respectively for another 18.0 years and 19.7 years.…”

mentioning

confidence: 99%

Frailty and aging

Sourdet

Rougé‐Bugat

Vellas

et al. 2012

The Journal of nutrition, health and aging

View full text Add to dashboard Cite

The prevalence of frailty syndrome in an older population from Spain. The Toledo study for healthy aging

Abstract: The prevalence of the frailty syndrome in older Spanish adults is high and similar to that reported in other populations in the Mediterranean basin.

Cited by 244 publications

References 30 publications

Do frailty and cognitive impairment affect dual-task cost during walking in the oldest old institutionalized patients?

Do frailty and cognitive impairment affect dual-task cost during walking in the oldest old institutionalized patients?

Multicomponent exercises including muscle power training enhance muscle mass, power output, and functional outcomes in institutionalized frail nonagenarians

Frailty and aging

Contact Info

Product

Resources

About