The prevalence of folic acid deficiency among adolescent girls living in Edirne, Turkey

Öner, Naci; Vatansever, Ülfet; Karasalihoğlu, Serap; Ekuklu, Galip; Çeltik, Coşkun; Biner, Betül

doi:10.1016/j.jadohealth.2005.03.027

Cited by 30 publications

(38 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…age was also detected. 9,[29][30][31] Similarly, our study revealed that seropositivity increases with age among our population; we found a seropositivity ratio of 95.2% in the adult age group which was very higher than the ratio of children. The causes of this increase are suggested as vaccination and cumulative exposure over time/age.…”

Section: Methodssupporting

confidence: 58%

Rubella seroprevalence among healthy individuals in Izmir, Turkey

Kurugöl

Midyat²,

Türkoğlu³

et al. 2011

Human Vaccines

View full text Add to dashboard Cite

Section: Methodssupporting

confidence: 58%

Rubella seroprevalence among healthy individuals in Izmir, Turkey

Kurugöl

Midyat²,

Türkoğlu³

et al. 2011

Human Vaccines

View full text Add to dashboard Cite

“…Folate deficiency, defined as ! 3 ng/ml serum folate, appeared in about 16% of 704 Turkish adolescent females aged 12-17 years [35] . Median and ranges appear to be similar to our results.…”

Section: Discussionmentioning

confidence: 99%

Methylenetetrahydrofolate Reductase 677CT Polymorphism and Cobalamin, Folate, and Homocysteine Status in Spanish Adolescents

Al-Tahan

Sola²,

Ruiz³

et al. 2008

Ann Nutr Metab

View full text Add to dashboard Cite

Background: Folate and cobalamin are responsible for healthy growth. However, the B-vitamin and homocysteine status of adolescents is not well known. The aim was to assess the status of folate, cobalamin, and homocysteine in healthy Spanish adolescents. Methods: Serum cobalamin, serum folate, homocysteine, methylenetetrahydrofolate reductase 677C>T variant, BMI, smoking habits, and Tanner stage were determined according to gender in 165 adolescents (84 females, 81 males; 13–18.5 years) using the Student’s t test, Mann-Whitney U test and χ² test, respectively. Interactions between socioeconomic status, age group, methylenetetrahydrofolate reductase polymorphism, BMI, smoking habits, Tanner stage, and vitamin status, respectively, were examined by ANOVA or Kruskal-Wallis H test (p < 0.05). Results: Boys had markedly higher homocysteine (males 8.92 (5.51–22.94) µmol/l; females 7.91 (5.09–13.86) µmol/l), whereas girls showed higher serum cobalamin concentrations (males 540.00 (268.00–946.47) pmol/l; females 594.82 (280.63–1,559.64) pmol/l). Data are shown as medians and the 2.5th to 97.5th percentiles in parentheses. Adolescents with the homozygous variant of methylenetetrahydrofolate reductase displayed significantly higher homocysteine and lower serum folate: normal 5.73 (3.09–10.73) ng/ml serum folate, 7.57 (4.94–12.94) µmol/l homocysteine; homozygous 4.10 (2.75–7.88) ng/ml serum folate, 10.83 (7.00–22.82) µmol/l homocysteine. Conclusion: The present study provides data on the folate, cobalamin, and homocysteine status of Spanish adolescents. To assure a better assessment, revision of references for adolescents is still needed.

show abstract

“…Folic acid deficiency leads to cardiovascular diseases, major depression, schizophrenia, Alzheimer's disease, and some carcinomas such as colorectal, uterine, cervical, lung and oesophageal. Various studies and randomised trials over the last three decades have shown that adequate intake of folate during early pregnancy reduces the risk of abnormalities in early embryonic brain development and specifically the risk of malformations of the embryonic brain/spinal cord, collectively referred to as NTDs [9][10][11][12][13][14]. Fortification of wheat flour to overcome folic acid deficiency diseases has been proven effective in many developed countries.…”

Section: Folic Acid Deficiencymentioning

confidence: 99%

Micronutrients Fortification of Rice by Parboiling: Lab Scale and Pilot Scale Studies

Thiruselvam¹,

Cheong²,

Mohan³

et al. 2014

J Nutr Food Sci

View full text Add to dashboard Cite

Deficiency diseases due to micronutrient insufficiency occur worldwide, especially in developing countries. Folic acid deficiency causes neural tube defects (NTD) and affects the central nervous system in 1:1000 births leading to anencephaly and spina bifida. Anaemia, a public health problem is caused by iron deficiency in 50% of the cases. Sub-clinical Vitamin A deficiency (VAD) causes morbidity and mortality, especially among young children and pregnant women. In young children, it can cause xerophthalmia and keratomalacia and lead to blindness or limited growth and weakening of the immune system, thereby increasing the risk of death. This study investigates the efficiency of using parboiling as a processing technique to fortify rice with folic acid, β-carotene and iron. Brown rice was parboiled by soaking with the micronutrients at the optimum conditions (70°C for 2 hours), steaming the soaked rice at 100°C for 1 hour and air drying until the moisture dropped to 10 ± 2% wb. Retention of these nutrients was assessed by analysis in the dried rice after milling (0 s, 60 s and 120 s) and in the cooked rice. The fortification was scaled up using 2.5 kg rice by parboiling with the highest concentration of the micronutrient mixture. The experimental process was compared with the conventional parboiling process for which the retention of the micronutrients was analysed. Retention of the nutrients in rice reduced during milling and cooking decreased by 10-15% (folic acid); 2-8% (β-carotene) and 4-5% (iron). Fortification of rice using parboiling is feasible. The laboratory scale method correlated well with the pilot scale.

show abstract

The prevalence of folic acid deficiency among adolescent girls living in Edirne, Turkey

Cited by 30 publications

References 30 publications

Rubella seroprevalence among healthy individuals in Izmir, Turkey

Rubella seroprevalence among healthy individuals in Izmir, Turkey

Methylenetetrahydrofolate Reductase 677CT Polymorphism and Cobalamin, Folate, and Homocysteine Status in Spanish Adolescents

Micronutrients Fortification of Rice by Parboiling: Lab Scale and Pilot Scale Studies

Contact Info

Product

Resources

About