The prevalence of diastolic dysfunction in adult hypertensive Nigerians

Ike, SO; Ikeh, V. O.

doi:10.4314/gmj.v40i2.36018

Cited by 18 publications

(13 citation statements)

References 15 publications

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“…26 The prevalence of diastolic dysfunction in our study was 84%. This is correlating with the studies done by Akintunde et al 21 and Ike et al 27 who studied the prevalence of diastolic dysfunction in adult hypertensive in Nigeria. However, this is higher than the 46% -48% as reported by Angiomachalelis et al 28 and De Mora et al 29 in European population.…”

Section: Discussionsupporting

confidence: 88%

Evaluation of diastolic function in hypertensive using echocardiography

Lavanya¹,

Singh

Sajja³

et al. 2015

Int J Res Med Sci

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INTRODUCTIONHigh blood pressure is more prevalent in the general population. Hypertension significantly contributes to cardiovascular (CV) morbidity and mortality by causing substantial structural and functional adaptations, including diastolic dysfunction (DD), left ventricular hypertrophy (LVH), ventricular and vascular stiffness. Chronic hypertension is the most common cause of diastolic dysfunction and failure. Abnormalities of ventricular relaxation and the consequences of diastolic dysfunction may signify myocardial end-organ damage in patients who have hypertension which precede ventricular hypertrophy. 1,2Isolated diastolic dysfunction is impairment of isovolumetric ventricular relaxation and decreased compliance of the left ventricle. Symptomatic diastolic dysfunction is called diastolic heart failure. With diastolic dysfunction, heart meets the body's metabolic needs, whether at rest or during exercise, but at a higher filling pressure's. With mild dysfunction, late filling increases ABSTRACT Background: Heart failure is one of the most common causes of cardiovascular morbidity along with mortality and hypertension is the most common cause of cardiac failure. Recent studies have shown that isolated diastolic dysfunction very often accompanies hypertensive heart disease. Aims: The present study was conducted to identify the risk of cardiac failure in hypertensive individuals by evaluating diastolic function using mitral inflow velocities of echocardiography. Methods: Subjects attending cardiology outpatient department for master health check up with age between 25 to 80 years were selected. The procedure was explained and consent was obtained from the subjects. All the subjects underwent a detailed clinical examination. Height, weight and blood pressure of the subjects was measured and BMI was calculated. Two-dimensional Doppler echocardiographic examinations were performed with an ultrasonographic system (Philips iE 133 Echo Doppler). The student t test, chi square test and logistic regression analysis were used to find the influence of ejection fraction and heart rate on diastolic function. Results: The trans-mitral inflow parameters on Doppler echocardiography such as E wave deceleration time (DT), isovolumetric relaxation time (IVRT) and early to late transmitral peak flow velocities ratio (E/A) were significantly different in hypertensive subjects on treatment having normal ejection fraction, when compared to normotensive subjects. We observed a decrease in E/A ratio and increase in DT, IVRT with hypertension. Conclusions: From the present study it can be concluded that hypertension is significantly associated with diastolic dysfunction of heart, even in subjects with normal systolic function.

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Section: Discussionsupporting

confidence: 88%

Evaluation of diastolic function in hypertensive using echocardiography

Lavanya¹,

Singh

Sajja³

et al. 2015

Int J Res Med Sci

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“…LV diastolic dysfunction has been demonstrated in hypertensive Nigerians by various workers [134][135][136][137][138] . Furthermore it has also been demonstrated in offspring of hypertensive individuals.…”

Section: Left Ventricular Diastolic Dysfunctionmentioning

confidence: 99%

Blood pressure, prevalence of hypertension and hypertension related complications in Nigerian Africans: A review

Ogah¹,

Okpechi²,

Chukwuonye³

et al. 2012

WJC

219

232

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To review studies on hypertension in Nigeria over the past five decades in terms of prevalence, awareness and treatment and complications. Following our search on Pubmed, African Journals Online and the World Health Organization Global cardiovascular infobase, 1060 related references were identified out of which 43 were found to be relevant for this review. The overall prevalence of hypertension in Nigeria ranges from 8%-46.4% depending on the study target population, type of measurement and cut-off value used for defining hypertension. The prevalence is similar in men and women (7.9%-50.2% vs 3.5%-68.8%, respectively) and in the urban (8.1%-42.0%) and rural setting (13.5%-46.4%). The pooled prevalence increased from 8.6% from the only study during the period from 1970-1979 to 22.5% (2000-2011). Awareness, treatment and control of hypertension were generally low with attendant high burden of hypertension related complications. In order to improve outcomes of cardiovascular disease in Africans, public health education to improve awareness of hypertension is required. Further epidemiological studies on hypertension are required to adequately understand and characterize the impact of hypertension in society.

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“…In 2006, Ike and VO Ikeh et al in study population of 69 males and 71 females found that prevalence of diastolic dysfunction in the hypertensive groups in this study was 82.86%. 6 Majority, i.e. 67 (78.8%) of the patients of diastolic dysfunction were from the age group of 51 -60 years out of 153 patients.…”

Section: Discussionmentioning

confidence: 99%

Study of Left Ventricular Diastolic Dysfunction in Systemic Hypertension and Evaluation by Doppler Echocardiography

Gupta¹,

Singh²,

Gupta³

et al. 2017

jemds

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BACKGROUND Persons suffering from Systemic Hypertension are likely to have cardiovascular side effects and this can be evaluated via a Doppler Echocardiography. Hypertension has been shown to be a good prognostic marker in the cardiovascular mortality. This study was done to detect the relationship between Hypertension and Left Ventricular Diastolic Dysfunction to evaluate its role in pathogenesis and its influence amidst other factors such as gender, smoking, hypercholesterolaemia and effect of lifestyle. MATERIALS AND METHODS 153 random patients presenting with or already having been diagnosed with systemic hypertension and not having any renal disease, diabetes mellitus, IHD, cardiomyopathy, valvular heart disease, pericardial disease etc. Consent was taken from all patients. History and examination was done according to a proforma. Blood pressure was taken along with haematological and biochemical examination and ECG was done to rule out secondary hypertension and IHD. All those in the inclusion criteria were taken for Echocardiography and M-mode measurements were taken and EF was calculated. RESULTS 55.6% were having diastolic dysfunction. Majority of them, i.e. 67 (72.8%) of those having diastolic dysfunction were from age group of 51-60 years. Overweight patients, i.e. 52 (33.98%) among which 27 (51.9%) were having diastolic dysfunction. 64 patients (41.8%) were having hypertension since 5-10 years, out of which 39 (60.9%) were having diastolic dysfunction. There are 3 patients above 15 years history of hypertension and all had diastolic dysfunction. CONCLUSION Our study revealed that there is positive co-relation of duration of hypertension with diastolic dysfunction. Other contributory factors found were greater age, male sex, urban population, obesity and smoking which contributed to development of diastolic dysfunction.

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The prevalence of diastolic dysfunction in adult hypertensive Nigerians

Cited by 18 publications

References 15 publications

Evaluation of diastolic function in hypertensive using echocardiography

Evaluation of diastolic function in hypertensive using echocardiography

Blood pressure, prevalence of hypertension and hypertension related complications in Nigerian Africans: A review

Study of Left Ventricular Diastolic Dysfunction in Systemic Hypertension and Evaluation by Doppler Echocardiography

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