The prevalence of depression and anxiety in patients with cancer in Iran: a systematic review and meta-analysis

Darvishi, Niloufar; Ghasemi, Hooman; Rahbaralam, Zahra; Shahrjerdi, Puneh; Akbari, Hakimeh; Mohammadi, Masoud

doi:10.1007/s00520-022-07371-1

Cited by 6 publications

(4 citation statements)

References 45 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the present study, patients with breast cancer and gastrointestinal cancer showed increased anxiety and depression. The fact that breast cancer patients are at high risk for developing psychiatric disorders such as depression and anxiety is consistent with the reported literature [11][12][13][14][15]. The prevalence of depression and anxiety was 42.6% and 40.9%, respectively, in a cross-sectional study involving 425 cancer patients from the Butaro Cancer Center of Excellence.…”

Section: Discussionsupporting

confidence: 89%

Prevalence of Depression and Anxiety Disorders Among Cancer Patients: An Insight From a Single Institute

Radhakrishnan,

Selvaraj,

Chidambaram

et al. 2023

Cureus

View full text Add to dashboard Cite

show abstract

Section: Discussionsupporting

confidence: 89%

Prevalence of Depression and Anxiety Disorders Among Cancer Patients: An Insight From a Single Institute

Radhakrishnan,

Selvaraj,

Chidambaram

et al. 2023

Cureus

View full text Add to dashboard Cite

show abstract

“…estimate is in line with a meta-analysis by Hashemi et.al, 41.9% (40). This finding is also congruent with recent conducted in Iran 40.9% (41), and China 38% (42). However, our estimate was quite high when compared to a meta-analysis of studies from developed settings, 15.09% (43).…”

Section: Discussionsupporting

confidence: 93%

“…The pooled estimate of depression among cancer patients in Ethiopia was 42.96% (95% CI: 34.98, 50.93). Our depression estimate was also in line with other meta-analyses from China 38% ( 42 ), and Iran 50.1% ( 41 ). Nevertheless, the depression prevalence estimate in this study was higher than in a previous meta-analysis conducted in Low- and Lower-Middle–Income Countries 21% ( 39 ).…”

Section: Discussionsupporting

confidence: 92%

Anxiety and depression among cancer patients in Ethiopia: a systematic review and meta-analysis

Geremew,

Abdisa,

Mazengia

et al. 2024

Front. Psychiatry

View full text Add to dashboard Cite

IntroductionAnxiety and depression are among the common comorbidities of people diagnosed with cancer. However, despite the progress in therapeutic options and outcomes, mental health care and support have lagged behind for cancer patients. Estimating the extent and determinants of mental health disorders among cancer patients is crucial to alert concerned bodies for action. In view of this, we aimed to determine the pooled prevalence and determinants of anxiety and depression among cancer patients in Ethiopia.MethodsRelevant literatures were searched on PubMed, African Journals Online, Hinari, Epistemonikos, Scopus, EMBASE, CINAHL, Cochrane Library, and Gray literature sources. Data were extracted into an Excel spreadsheet and analyzed using STATA 17 statistical software. The random effect model was used to summarize the pooled effect sizes with their respective 95% confidence intervals. The I2 statistics and Egger’s regression test in conjunction with the funnel plot were utilized to evaluate heterogeneity and publication bias among included studies respectively.ResultsA total of 17 studies with 5,592 participants were considered in this review. The pooled prevalence of anxiety and depression among cancer patients in Ethiopia were 45.10% (95% CI: 36.74, 53.45) and 42.96% (95% CI: 34.98, 50.93), respectively. Primary and above education (OR= 0.76, 95% CI: 0.60, 0.97), poor social support (OR= 2.27, 95% CI: 1.29, 3.98), occupational status (OR= 0.59; 95% CI: 0.43, 0.82), advanced cancer stage (OR= 2.19, 95% CI: 1.38, 3.47), comorbid illness (OR= 1.67; 95% CI: 1.09, 2.58) and poor sleep quality (OR= 11.34, 95% CI: 6.47, 19.89) were significantly associated with depression. Whereas, advanced cancer stage (OR= 1.59, 95% CI: 1.15, 2.20) and poor sleep quality (OR= 12.56, 95% CI: 6.4 1, 24.62) were the factors associated with anxiety.ConclusionThis meta-analysis indicated that a substantial proportion of cancer patients suffer from anxiety and depression in Ethiopia. Educational status, occupational status, social support, cancer stage, comorbid illness and sleep quality were significantly associated with depression. Whereas, anxiety was predicted by cancer stage and sleep quality. Thus, the provision of comprehensive mental health support as a constituent of chronic cancer care is crucial to mitigate the impact and occurrence of anxiety and depression among cancer patients. Besides, families and the community should strengthen social support for cancer patients.Systematic Review Registrationhttps://www.crd.york.ac.uk/prospero/, identifier CRD42023468621.

show abstract

“…Anxiety is the most widely reported psychological disorder found in up to 38% of cancer patients 2 .Age, gender, and cancer location are believed to be mediators, with higher anxiety levels generally seen in younger patients 7 . An Iranian meta-analysis in 2022 and another meta-analysis conducted in Iran revealed a higher prevalence of both anxiety and depression, as well as depression alone in breast cancer patients, respectively 8 , 9 . Moreover, depression is a common issue among cancer patients, affecting up to 16% 10 .…”

Section: Introductionmentioning

confidence: 99%

Prospective study of predictors for anxiety, depression, and somatization in a sample of 1807 cancer patients

Velasco-Durantez,

Cruz-Castellanos,

Hernandez

et al. 2024

Sci Rep

View full text Add to dashboard Cite

In cancer patients, psychological distress, which encompasses anxiety, depression, and somatization, arises from the complex interplay of emotional and behavioral reactions to the diagnosis and treatment, significantly influencing their functionality and quality of life. The aim was to investigate factors associated with psychological distress in cancer patients. This prospective and multicenter study, conducted by the Spanish Society of Medical Oncology (SEOM), included two cohorts of patients with cancer (localized resected or advanced unresectable). They completed surveys assessing psychological distress (BSI-18) before and after cancer treatment and coping (MINI-MAC) and spirituality (FACIT-sp) prior to therapy. A multivariable logistic regression analysis and a Structural Equation Modeling (SEM) were conducted. Between 2019 and 2022, 1807 patients were evaluated, mostly women (54%), average age 64 years. The most frequent cancers were colorectal (30%), breast (25%) and lung (18%). Men had lower levels of anxiety and depression (OR 0.66, 95% CI 0.52–0.84; OR 0.72, 95% CI 0.56–0.93). Colorectal cancer patients experienced less anxiety (OR 0.63, 95% CI 0.43–0.92), depression (OR 0.55, 95% CI 0.37–0.81), and somatization (OR 0.59, 95% CI 0.42–0.83). Patients with localized cancer and spiritual beliefs had reduced psychological distress, whereas those with anxious preoccupation had higher level. SEM revealed a relationship between psychological distress and coping strategies, emphasizing how baseline anxious preoccupation exacerbates post-treatment distress. This study suggests that age, sex, extension and location of cancer, coping and spirituality influence psychological distress in cancer patients.

show abstract

The prevalence of depression and anxiety in patients with cancer in Iran: a systematic review and meta-analysis

Cited by 6 publications

References 45 publications

Prevalence of Depression and Anxiety Disorders Among Cancer Patients: An Insight From a Single Institute

Prevalence of Depression and Anxiety Disorders Among Cancer Patients: An Insight From a Single Institute

Anxiety and depression among cancer patients in Ethiopia: a systematic review and meta-analysis

Prospective study of predictors for anxiety, depression, and somatization in a sample of 1807 cancer patients

Contact Info

Product

Resources

About