The prevalence of dental fluorosis and exposure to fluoride in drinking water: A systematic review

Goodarzi, Fatemeh; Mahvi, Amir Hossein; Hosseini, Mostafa; Nodehi, Ramin Nabizadeh; Kharazifard, Mohammad Javad; Parvizishad, Mina; Cheraghi, Zahra

doi:10.15171/joddd.2016.021

Cited by 32 publications

(25 citation statements)

References 19 publications

(16 reference statements)

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“…Evidences from other studies also indicated that dental fluorosis is well recognized health problem (2,4,8,32). According to the systematic review conducted in India, the pooled estimation of dental fluorosis was reported as 12.9% (33), which is much more lower than this result. Another study in Iran revealed the prevalence of dental fluorosis was 61% (34),which is more than the pooled estimation of this review.…”

Section: Pooled Prevalence Of Dental Fluorosismentioning

confidence: 67%

Fluoride Concentration in Ground Water and Prevalence of Dental Fluorosis in Ethiopian Rift Valley: Systematic Review and Meta-Analysis

Enyew

Beyene

Abebe

et al. 2019

Preprint

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Background High fluoride concentrations in ground water is a serious health, social and economic problem in developing countries. The Ethiopian Rift Valley is associated with high fluoride levels in ground water where deep wells are the major source of drinking water supply. Many epidemiological studies on fluoride concentration and its adverse effects have been carried out. However, the result is scattered in different studies which needs systematically summarized for utilization.Objective The aim of this research is to estimate the pooled level of fluoride concentration in ground water and the prevalence of dental fluorosis in Ethiopian rift valley.Methods MEDLINE/PubMed, Cochrane library and Google scholar databases were systematically searched for studies reporting the mean concentration of fluoride in ground water and prevalence of dental fluorosis in Ethiopian Rift valley. We identified search terms by extracting key terms from reviews and selected relevant papers and review medical subject headings for relevant and appropriate terms.Results The mean concentration of fluoride in ground water and the prevalence of dental fluorosis were pooled from eleven and nine primary studies conducted in Ethiopian Rift Valley respectively. The pooled mean concentration of fluoride in ground water therefore was 6.03 mg/l (95% CI; 4.72–7.72, p < 0.001) and the pooled prevalence of dental fluorosis among residents in Ethiopian rift valley was 32% (95% CI: 25, 39%, p<0.001), 29% (95% CI: 22, 36%, p<0.001) and 24% (95% CI: 17, 32%, p<0.001 for mild, moderate and sever fluorosis respectively. The overall prevalence of dental fluorosis is 28% (95% CI: 24, 32%, p<0.001).Conclusions The mean concentration of fluoride in ground water in Ethiopian rift valley is nearly four times greater than the WHO guideline (1.5mg/l). Relatively high-level pooled prevalence of dental fluorosis was also seen in Ethiopian rift valley. Therefore, further studies covering the temperature, exposure time and other intake path ways including diet with large sample size is recommended. Interventional projects should conduct to decrease the concentration of fluoride in the ground drinking water source.

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Section: Pooled Prevalence Of Dental Fluorosismentioning

confidence: 67%

Fluoride Concentration in Ground Water and Prevalence of Dental Fluorosis in Ethiopian Rift Valley: Systematic Review and Meta-Analysis

Enyew

Beyene

Abebe

et al. 2019

Preprint

View full text Add to dashboard Cite

show abstract

Section: Pooled Prevalence Of Dental Fluorosismentioning

confidence: 67%

Fluoride Concentration in Ground Water and Prevalence of Dental Fluorosis in Ethiopian Rift Valley: Systematic Review and Meta-Analysis

Enyew

Beyene

Abebe

et al. 2019

Preprint

View full text Add to dashboard Cite

Background: The concentration of fluoride in ground drinking water greater than the world health organization standard value imposes a serious health, social and economic problem in developing countries. In the Ethiopian Rift Valley where deep wells are the major source of drinking water, high fluoride level is expected. Though many epidemiological studies on fluoride concentration and its adverse effects have been conducted in the region, the result is highly scattered and needs systematically summarized for better utilization. Objective: This research is aimed at estimating the pooled level of fluoride concentration in ground drinking water and the prevalence of dental fluorosis among Ethiopian rift valley residences. Methods: Cochrane library, MEDLINE/PubMed and Google scholar databases were searched for studies reporting the mean concentration of fluoride in ground water and prevalence of dental fluorosis in Ethiopian Rift valley. Search terms were identified by extracting key terms from reviews and selected relevant papers and review medical subject headings for relevant terms. Results: The mean fluoride level in ground water and the prevalence of dental fluorosis were pooled from eleven and nine primary studies conducted in Ethiopian Rift Valley respectively. The pooled mean level of fluoride in ground water therefore was 6.03 mg/l (95% CI; 4.72–7.72, p < 0.001) and the pooled prevalence of dental fluorosis among residents in Ethiopian rift valley was 32% (95% CI: 25, 39%, p<0.001), 29% (95% CI: 22, 36%, p<0.001) and 24% (95% CI: 17, 32%, p<0.001 for mild, moderate and sever dental fluorosis respectively. The overall prevalence of dental fluorosis is 28% (95% CI: 24, 32%, p<0.001). Conclusions: Though, the concentration level varies across different part of the rift valley region, still the level of fluoride in ground drinking water is greater than the WHO standard value (1.5mg/l). Relatively high-level pooled prevalence of dental fluorosis was also seen in Ethiopian rift valley. Therefore, further studies covering the temperature, exposure time and other intake path ways with large sample size is recommended. Interventional projects should be implemented to decrease the concentration of fluoride in the ground drinking water source. Key words: Dental fluorosis, Fluoride, Concentration, Rift Valley, Ethiopia

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“…According to a systematic review of Reddy et al [18], the estimate of dental fluorosis in a population that uses fluoridated water with a fluoride content between 0.7 and 1.2 ppm is 29.8% among the studies analyzed. In our study, the prevalence in the studied cities was lower than this estimate [18].…”

Section: Resultsmentioning

confidence: 99%

“…The choice of these cities was intentional because they belonged to the same region, had a similar population number (Morro da Fumaça -17,373 inhabitants and Cocal do Sul, 16,301 [19] [18].…”

Section: Methodsmentioning

confidence: 99%

Retrospective analysis of the fluoride level in the public water supply and its correlation with dental fluorosis at two cities of South Santa Catarina

Marcon¹,

Mezzari

Ceretta

et al. 2018

RSBO

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The prevalence of dental fluorosis and exposure to fluoride in drinking water: A systematic review

Cited by 32 publications

References 19 publications

Fluoride Concentration in Ground Water and Prevalence of Dental Fluorosis in Ethiopian Rift Valley: Systematic Review and Meta-Analysis

Fluoride Concentration in Ground Water and Prevalence of Dental Fluorosis in Ethiopian Rift Valley: Systematic Review and Meta-Analysis

Fluoride Concentration in Ground Water and Prevalence of Dental Fluorosis in Ethiopian Rift Valley: Systematic Review and Meta-Analysis

Retrospective analysis of the fluoride level in the public water supply and its correlation with dental fluorosis at two cities of South Santa Catarina

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