The prevalence of COVID vaccine acceptance among pregnant women: A systematic review and meta-analysis

Halemani, Kurvatteppa; Dhiraaj, Prof sanjay; Latha, T; Mishra, Prabhaker; Issac, Alwin

doi:10.1016/j.cegh.2022.101144

Cited by 8 publications

(6 citation statements)

References 35 publications

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“…Several studies identified the perceived severity of COVID-19 infection ( 74 ), concerns for adverse reactions to COVID-19 vaccine ( 23 , 41 , 45 , 61 ), and concerns about side effects and safety of COVID vaccines ( 29 , 38 , 45 , 52 , 53 , 68 , 75 , 80 ) as the common predictors of COVID-19 vaccine acceptance. In addition, Halemani et al ( 45 ) stated that adverse effects were the top indicators for rejecting the COVID vaccine. On the other hand, a lower level of perceived vaccine harms ( 73 , 74 ) was positively related to CVI.…”

Section: Resultsmentioning

confidence: 99%

“…The association between perceived susceptibility (perceived risk of contracting COVID-19) and CVI was reported in 17 studies. Perceiving susceptibility to COVID-19 infection ( 1 , 35 , 41 , 43 , 45 , 48 , 52 , 53 , 59 , 63 , 73 , 74 ), fear about COVID-19 ( 41 , 46 , 59 ) and anxiety about COVID-19 ( 47 ) were key drivers of CVI. In addition, the risks of infections were one of the main reasons for accepting the COVID vaccine in pregnant women ( 45 ).…”

Section: Resultsmentioning

confidence: 99%

“…Perceiving susceptibility to COVID-19 infection ( 1 , 35 , 41 , 43 , 45 , 48 , 52 , 53 , 59 , 63 , 73 , 74 ), fear about COVID-19 ( 41 , 46 , 59 ) and anxiety about COVID-19 ( 47 ) were key drivers of CVI. In addition, the risks of infections were one of the main reasons for accepting the COVID vaccine in pregnant women ( 45 ).…”

Section: Resultsmentioning

confidence: 99%

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The determinants of COVID-19 vaccination intention: a meta-review

Limbu¹,

Gautam²

2023

Front. Public Health

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BackgroundA large number of systematic reviews have been published that synthesized various determinants of COVID-19 vaccination intention (CVI). However, they reported inconsistent evidence. Therefore, we conducted a meta-review (systematic review of systematic reviews) to provide a comprehensive synthesis of factors influencing CVI.MethodsThis meta-review was conducted in accordance with PRISMA guidelines. PubMed, Scopus, Web of Science, and CINAHL were searched for systematic reviews published from 2020 to 2022 that examined the determinants of CVI. AMSTAR-2 critical appraisal tool was used to ensure the quality of included reviews, and ROBIS tool was used to evaluate the risk of bias.ResultsGlobally, the average rate of COVID-19 vaccination intention was 56.97%. We identified 21 main determinants of CVI: socio-demographic, geographical location, social, political, government role, study timeline, attitude, perceived severity, perceived susceptibility, perceived benefits, perceived barriers, self-efficacy and perceived behavioral control, norms, trust, conspiracy theory/propaganda/misinformation, knowledge, information and communication, vaccination recommendation, vaccination history, history of COVID-19 infection, and health status and well-being.ConclusionsThese results suggest that COVID-19 vaccination intention is a complex process and is affected by numerous multidimensional factors. Therefore, integrated communication strategies and multifaceted interventions may be effective for improving vaccination intention against COVID-19.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

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The determinants of COVID-19 vaccination intention: a meta-review

Limbu¹,

Gautam²

2023

Front. Public Health

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“…The vaccination of breastfeeding women against SARS-CoV-2 is recommended by health agencies to protect both the mother and infant [3][4][5] ; SARS-CoV-2-speci c antibodies can be found in both breast milk and infant stool post-vaccination 6,7 . However, in several countries, vaccination rates among lactating mothers are relatively low due to fears of unpredictable adverse effects on their infants [8][9][10][11] . This reluctance is a cause of concern, as breast milk antibodies not only confer protection to invading pathogens but can also shape the infant's immune system development by facilitating the establishment and maintenance of the infants' gut microbiome 12,13 .…”

Section: Introductionmentioning

confidence: 99%

COVID-19 mRNA vaccine-mediated antibodies in human breast milk and their association with breast milk microbiota composition

Zhao

Lok

Sin

et al. 2023

Preprint

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Newborns can acquire immunological protection to SARS-CoV-2 through vaccine-conferred antibodies in human breast milk. However, there are some concerns around lactating mothers with regards to potential short- and long-term adverse events and vaccine-induced changes to their breast milk microbiome composition, which helps shape the early-life microbiome. Here, we recruited 49 lactating mothers from Hong Kong who received two doses of BNT162b2 vaccine between June 2021 and August 2021. Breast milk samples were self-collected by participating mothers pre-vaccination, one week post-first dose, one week post-second dose, and one month post-second dose. The levels of SARS-CoV-2 spike-specific IgA and IgG in breast milk peaked at one week post-second dose. Subsequently, the levels of both antibodies rapidly waned in breast milk, with IgA levels returning to baseline levels one month post-second dose. The richness and composition of human breast milk microbiota changed dynamically throughout the vaccination regimen, but the abundances of beneficial microbes such as Bifidobacterium species did not significantly change after vaccination. In addition, we found that baseline breast milk bacterial composition can predict spike-specific IgA levels at one week post-second dose (Area Under Curve: 0.72, 95% confidence interval: 0.58–0.85). Taken together, our results suggest that infants may acquire immunological protection from breast milk from SARS-CoV-2-vaccinated mothers by both the vertical transmission of antibodies and beneficial microbiota.

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“…However, mental health is the major contributing factor to low birth weight and preterm delivery. Therefore, balancing diet and a safe environment is important for pregnant and lactating women [ 5 - 7 ].…”

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confidence: 99%

Impact of probiotic on anxiety and depression symptoms in pregnant and lactating women and microbiota of infants: A systematic review and meta-analysis

et al. 2023

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Background Probiotics are non-invasive therapies composed of live bacteria and yeast. Administration of prebiotics improved the health status of pregnant and lactating women, as well as newborns. This review aimed to appraise the evidence concerning the effectiveness of probiotics on the mental health of pregnant women, lactating mother and the microbiota of the newborn. Methods This systematic review and meta-analysis ascertained quantitative studies published in Medline (PubMed), Clinical Key, EMBASE, Cumulative Index to Nursing and Allied Health Literature (CINAHL), the Cochrane Library, and Google scholar. Two authors independently screened and extracted the data from the primary studies that analysed the efficacy of probiotics on the mental health of pregnant and lactating women and the microbiota of the newborn. We adopted Cochrane Collaboration guidelines and reported using the Preferred Reporting Items for Systematic review and Meta-Analysis (PRISMA) statement. The qualities of included trials were assessed by Cochrane collaboration's risk of bias tool (ROB-2). Results Sixteen trials comprised 946 pregnant women, 524 were lactating mothers, and 1678 were infants. The sample size of primary studies ranged from 36 to 433. Probiotics were administered as interventions, using either a single strain of Bifidobacterium or Lactobacillus or a double-strain combination of Lactobacillus and Bifidobacterium. Probiotics supplementation reduced anxiety in pregnant (n = 676, standardised mean difference (SMD) = 0.01; 95% confidence interval (CI) = -0.28,0.30, P = 0.04, I 2 = 70) and lactating women (n = 514, SMD = -0.17; 95% CI = -1.62,1.27, P = 0.98, I 2 = 0). Similarly, probiotics decreased depression in pregnant (n = 298, SMD = 0.05; 95% CI = -0.24,0.35, P = 0.20, I 2 = 40) and lactating women (n = 518, SMD = -0.10; 95% CI = -1.29,-1.05, P = 0.11, I 2 = 60%). Similarly, probiotics supplementation improved the gut microbiota and reduced the duration of crying, abdominal distension, abdominal colic and diarrhoea. Conclusion Non-invasive probiotic therapies are more useful to pregnant and lactating women and newborns. Registration The review protocol was registered with PROSPERO (CRD42022372126).

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The prevalence of COVID vaccine acceptance among pregnant women: A systematic review and meta-analysis

Cited by 8 publications

References 35 publications

The determinants of COVID-19 vaccination intention: a meta-review

The determinants of COVID-19 vaccination intention: a meta-review

COVID-19 mRNA vaccine-mediated antibodies in human breast milk and their association with breast milk microbiota composition

Impact of probiotic on anxiety and depression symptoms in pregnant and lactating women and microbiota of infants: A systematic review and meta-analysis

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