The prevalence of cirrhotic cardiomyopathy according to different diagnostic criteria

Abstract

Funding informationDr Marcel Razpotnik received for the cirrhotic cardiomyopathy project a promotional award for young investigators from the Austrian Society of Ultrasonography (Österreichische Gesellschaft für Ultraschall in der Medizin -ÖGUM).

Role of anti-beta-1-adrenergic receptor antibod ies in cardiac dysfunction in patients with cirrhotic cardiomyopathy

“…The exact prevalence of CCM in cirrhotic patients remains unclear but recent estimates place it around 60% [27,28]. In our study it was only 15%.…”

“…Since approximately 7%-21% of deaths after liver transplantation result from cardiovascular complications [12], it is possible that the new CCC criteria may be too restrictive to apply to advanced-cirrhotic patients. Another recent publication compared the two diagnostic criteria in 122 patients with cirrhosis [28]. They found that the overall prevalence of cirrhotic cardiomyopathy was similar for the old criteria (67.2%), compared to the new (55.7%, P=0 .9).…”

Cirrhotic cardiomyopathy prevalence according to the new criteria

“…A recent study we performed, retrospectively evaluated CCM in 141 liver transplant candidates and found it to affect 34.8%, per the CCMC criteria. 3 However, in the current study, 1 the CCMC criteria yielded a prevalence that is as high as 55.7%. In reviewing the data provided, it appears that the higher prevalence is due to considering patients with GLS >22% as having CCM.…”

Relationship of Nonalcoholic Fatty Liver Disease and Heart Failure With Preserved Ejection Fraction

“…Cirrhotic cardiomyopathy is a clinical syndrome of chronic cardiac dysfunction that occurs in patients with cirrhosis (irrespective of the etiology) with no known cardiac disease and is characterized by high cardiac output at rest and blunted contractility response to stress (whether physiological, pathological, or pharmacologic stress) and/or altered diastolic relaxation with abnormal electrophysiological changes ( 71 ). It is estimated that about 60% of patients with cirrhosis have cirrhotic cardiomyopathy ( 72 ). Proposed redefined criteria were proposed by the Cirrhotic Cardiomyopathy Consortium in 2019 ( Table 2 ) ( 73 ).…”