The prevalence, incidence and prognostic value of the Brugada-type electrocardiogram

Abstract

The Brugada-type ECG is not a very rare condition in the adult Japanese population. Subjects with a Brugada-type ECG have an increased risk of unexpected death.

Long‐Term Prognosis of Brugada‐Type ECG and ECG With Atypical ST‐Segment Elevation in the Right Precordial Leads Over 20 Years: Results From the Circulatory Risk in Communities Study (CIRCS)

“…In keeping with previous reports,4, 7, 9, 10, 21, 22 there was a male predominance among participants with BrS. In the present study, no SCD among participants with type 1 BrS and only 1 SCD among those with non–type 1 BrS was observed during the follow‐up period, which was consistent with previous community‐based studies,6, 8, 9, 12, 14 except for the Atomic Heart Study 11. In that study, the definition of type 1 BrS, which was characterized by the coexistence of coved and saddleback morphology with J point elevation ≥0.1 mV in V 1 through V 3 , was different from that in the second consensus report 3…”

“…The data from previous studies vary regarding prevalence and prognosis for patients with Brugada‐type ECG (BrS) because of different populations (eg, general population, office workers),4, 5, 6, 7, 8, 9 different ECG definitions,5, 6, 9, 10, 11, 12 relatively short‐term follow‐up,5, 6, 9, 10, 12, 13 or poorly defined SCD 5, 6, 7, 8, 10, 11, 13, 14…”

Epidemiology of Arrhythmias and Sudden Cardiac Death in Asia

“…67 The results of representative early population-based cohort studies are summarized in Table 3. [70][71][72][73][74][75][76][77][78][79] The estimated prevalence of BrS ranges from 0.02% to 0.1% in Europe and from 0.1% to 0.25% in Asia.…”

Relationships Between Depolarization Abnormality and Repolarization Abnormality in Patients with Brugada Syndrome:

“…However, the prevalence of Brugada-type ECGs in Japan is only 0.27% on average (range 0.14%-0.7%). 17,[32][33][34][35] In addition, this study was performed in one institute. Thus, further prospective studies using larger numbers of patients are needed to evaluate the reproducibility of these findings.…”