The prevalence and significance of periodic leg movements during sleep in patients with congestive heart failure

Skomro, Robert; Silva, Rogerio; Alves, Rosana Cardoso; Figueiredo, Adelaide C.; Lorenzi-Filho, Geraldo

doi:10.1007/s11325-008-0207-5

Cited by 35 publications

(17 citation statements)

References 32 publications

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“…These factors, although not explored in this study, could contribute to poor sleep quality in patients with HCM. Moreover, a recent study showed that periodic leg movements were common among patients with congestive heart failure but did not correlate with sleep architecture [20]. The PSQI, in addition to providing a general score that evaluates the overall quality of sleep, allows the separation of sleep quality into 7 items.…”

Section: Discussionmentioning

confidence: 99%

Sleep Quality and Quality of Life in Patients with Hypertrophic Cardiomyopathy

Pedrosa¹,

Lima

Drager³

et al. 2010

Cardiology

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Objectives: To evaluate clinical predictors of poor sleep quality and quality of life (QOL) in patients with hypertrophic cardiomyopathy (HCM). Methods: Consecutive stable patients with HCM were evaluated for the risk of obstructive sleep apnea (OSA) by the Berlin Questionnaire, daytime sleepiness by the Epworth Sleepiness Scale, sleep quality by the Pittsburgh Sleep Questionnaire Index and QOL by the Minnesota Living with Heart Failure Questionnaire. Asymptomatic subjects without HCM were used as controls. Results: We studied 84 patients with HCM and 42 controls who were similar with regard to gender (49 vs. 50% males), age [52 (38–62) vs. 47 (33–58) years] and body mass index (27 ± 4 vs. 27 ± 5). HCM diagnosis, high risk for OSA and female gender were independently associated with poor sleep quality in the entire population. Among patients with HCM, poor QOL was independently associated with poor sleep quality, New York Heart Association functional class and diuretic therapy. Conclusion: Poor sleep quality is very common in patients with HCM and may have a negative impact on the QOL, which in turn is an important marker of prognosis in patients with cardiomyopathies.

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Section: Discussionmentioning

confidence: 99%

Sleep Quality and Quality of Life in Patients with Hypertrophic Cardiomyopathy

Pedrosa¹,

Lima

Drager³

et al. 2010

Cardiology

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“…The AHI was not different between the groups. 57 The previous 2 studies (Javaheri and Skomro et al) showed a similar prevalence of PLMI in ~20% in the CHF population.…”

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confidence: 80%

Cardiovascular comorbidity in patients with restless legs syndrome: current perspectives

Vargas-Pérez¹,

Bagai²,

Walters³

2017

JPRLS

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“…Even among those studies, the study by Yumino and colleagues in which some patients with severely impaired LVEF and with NYHA class IV symptoms were enrolled showed a relatively greater prevalence of PLM (i.e., 37%) 14 compared with the other 2 studies (19% and 20%). 12, 13 On the other hand, a more recent study by Yoshihisa and colleagues in which patients with either reduced or preserved LVEF and those with variable NYHA class (i.e., class I-IV) disease were enrolled showed that the prevalence of severe PLM, defined as PLMI ≥30/h, was 16%; this prevalence is less than that of severe PLM in the present study, in which only patients with reduced LVEF and more symptomatic patients following an episode of ADHF were enrolled. If fact, a recent study by Yoshihisa and colleagues reported that patients with severe PLM have impaired exercise capacity.…”

Section: Other Baseline Data and Outcome Data Collectionmentioning

confidence: 99%

Impact on Clinical Outcomes of Periodic Leg Movements During Sleep in Hospitalized Patients Following Acute Decompensated Heart Failure

Yatsu

Kasai

Suda

et al. 2017

Circ J

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Background: Periodic leg movements during sleep (PLM) are characterized by regularly recurring movement of the legs during sleep. Although PLM is common and a predictor of death in patients with chronic heart failure, the clinical significance of PLM in hospitalized patients with a reduced left ventricular ejection fraction (LVEF) following acute decompensated heart failure (ADHF) remains unknown. Methods and Results:After initial improvement of acute signs and symptoms of ADHF, 94 consecutive patients with reduced LVEF who underwent polysomnography were enrolled. They were divided into 2 groups based on the presence or absence of severe PLM defined as PLM index ≥30. The risks for clinical events, composite of all-cause death and rehospitalization, were assessed using a stepwise multivariable Cox proportional model including variables showing P<0.10 in univariate analyses. Severe PLM was observed in 21 patients (22%). At a median follow-up of 5.2 months, 30 patients experienced clinical events (32%). In the multivariable analysis, the presence of severe PLM was significantly associated with increasing clinical events (hazard ratio, 2.16; 95% confidence interval, 1.03-4.54; P=0.042) independent of hemoglobin level and the severity of sleep-disordered breathing. Conclusions:In hospitalized patients with systolic dysfunction following ADHF, severe PLM was prevalent and significantly associated with increased risk of death and/or rehospitalization.

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The prevalence and significance of periodic leg movements during sleep in patients with congestive heart failure

Abstract: The prevalence of PLMs in consecutive sample of adult CHF outpatients was 19%. There were no differences in subjective daytime sleepiness, sleep architecture, AHI, and severity of CHF in subjects with and without PLMs. PLMs caused a small but statistically significant cardiac acceleration.

Cited by 35 publications

References 32 publications

Sleep Quality and Quality of Life in Patients with Hypertrophic Cardiomyopathy

Sleep Quality and Quality of Life in Patients with Hypertrophic Cardiomyopathy

Cardiovascular comorbidity in patients with restless legs syndrome: current perspectives

Impact on Clinical Outcomes of Periodic Leg Movements During Sleep in Hospitalized Patients Following Acute Decompensated Heart Failure

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