The Prevalence and Risk Factors of Gallstone Among Adults in South-East of Iran: A Population-Based Study

Ansari‐Moghaddam, Alireza; Khorram, Alireza; Miri-Bonjar, Mahmodreza; Mohammadi, Mahdi

doi:10.5539/gjhs.v8n4p60

Cited by 28 publications

(26 citation statements)

References 23 publications

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“…This is in agreement with studies done by Novacek G, [10] where occurrence of gallstones was found to be 2 to 3 times higher. Moghaddam AA et al [11] reported a 2.73 times higher incidence of gallstones in female. The conversion rate in our study was found to be 7.5%.…”

Section: Discussionmentioning

confidence: 97%

To Study the Level of High-Sensitive C-Reactive Protein With Ultrasonographic Findings as a Predictive Factor for Difficult Laparoscopic Cholecystectomy

Choudhury¹,

Paul²

2018

jemds

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BACKGROUND Laparoscopic cholecystectomy is considered to be the gold standard for the treatment of gallstones. However, conversion of laparoscopic cholecystectomy to open cholecystectomy is done by surgeons in difficult cases. The aim of the study is to use Hs-CRP level in correlation with ultrasonographic findings to predict difficult laparoscopic cholecystectomy pre-operatively. It would help in anticipating a difficult laparoscopic cholecystectomy pre-operatively, better counselling of patients, avoiding unnecessary laparoscopic dissection and hence less morbidity. MATERIALS AND METHODS This is an observational study. It is an original study conducted in the Department of General Surgery of Gauhati Medical College and Hospital. The study group included 40 consecutive patients undergoing laparoscopic cholecystectomy for cholelithiasis. Cholelithiasis was diagnosed on the basis of ultrasonography done pre-operatively. Hs-CRP level was determined pre-operatively and post-operatively after 6 hrs. and 12 hrs. It was correlated with ultrasonographic findings to predict difficult cholecystectomy. RESULTS The mean value of Hs-CRP was found to be 9.68 mg/L pre-operatively, 21.88 mg/L at 6 hours and 26.57 mg/L at 12 hours. While the mean value of Hs-CRP was found to be significantly higher in cases, which needed conversion. USG findings such as presence of adhesion, GB wall thickness more than 3 mm and narrow Calot's triangle were found to be significant predictors for conversion. On correlation, the positive predictive value increased. CONCLUSION Pre-operative values of Hs-CRP when combined with ultrasonography findings can predict difficult cholecystectomy. It will help in better selection of patients and help in decreasing morbidity.

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Section: Discussionmentioning

confidence: 97%

To Study the Level of High-Sensitive C-Reactive Protein With Ultrasonographic Findings as a Predictive Factor for Difficult Laparoscopic Cholecystectomy

Choudhury¹,

Paul²

2018

jemds

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“…Studies have shown that the use of oral contraceptives and multiparity increase the risk of biliary stasis and therefore leads to gallstones formation. [11,12] The gallbladder motility disorder continues for about 1 year after delivery. The frequency of pregnancy and multiparity are the major risk factors for cholesterol gallstones.…”

Section: Discussionmentioning

confidence: 99%

Acute biliary pancreatitis during pregnancy and post delivery period

Hot

Eğin

Gökçek

et al. 2019

Ulus Travma Acil Cerrahi Derg

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BACKGROUND: Acute pancreatitis has an incidence of approximately 1 in 1000 to 5000 pregnancies, and is most often seen in the third trimester or the postpartum period. The most common cause of pregnancy-related acute pancreatitis is cholelithiasis, which accounts for more than 65% of cases. The aim of this study was to present a detailed analysis of 4 years of experience with cases of acute biliary pancreatitis related to pregnancy from a single center. METHODS:The medical records of 55 consecutive patients who were hospitalized in the emergency surgery clinic for acute biliary pancreatitis related to pregnancy between January 1, 2014 and January 1, 2018 were examined in this single-center, retrospective study. RESULTS:Fifty-five patients with acute biliary pancreatitis related to pregnancy were included in the study. Of the 55 women, 13 (24%) were in the pregnant group, 28 (51%) in the postpartum (6 weeks) group, and 14 (25%) were in the 1-year (6 weeks-1 year) group. There was no statistically significant difference between the 3 groups. The most appropriate treatment for each patient was targeted. Six (10%) patients had recurrent acute pancreatitis. There was no maternal or fetal mortality or morbidity. CONCLUSION:Acute biliary pancreatitis related to pregnancy is not limited to pregnant women, and the incidence of these cases was greater than expected. Acute biliary pancreatitis related to pregnancy can be successfully managed with conservative treatment because it usually has a mild to moderate clinical course. However, the surgeon should keep an early cholecystectomy in mind for patients other than those in the first trimester.

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“…[26] Increasing age is a risk factor for GD and possibly explained by long-term exposure to other related environmental risk factors. [27] Moreover, an elevated fasting blood glucose level is another factor related to coronary artery disease as well as GD. [28] Elevated fasting blood glucose and DM can affect cholesterol and lipoprotein metabolism and cause defective gallbladder contractility.…”

Section: Discussionmentioning

confidence: 99%

The association between gallstone disease and plaque in the abdominopelvic arteries

et al. 2017

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Background:The aim of this study was to assess the atheromatous plaque, in the abdominopelvic arteries as a marker of cardiac risk in patients with or without gallstone disease (GD).Materials and Methods:A total of 136 patients were enrolled in this cross-sectional study. Forty-eight patients had GD and the remaining 88 patients did not. The presence or absence of gallstones was noted during abdominal ultrasonography while vascular risk factors such as plaque formation, intima-media thickness, plaque calcification, mural thrombus, stenosis, aneurysm, and inflammation were recorded during an abdominopelvic computed tomography scan. In addition, percentage of the abdominopelvic aorta surface covered by atheromatous plaque was calculated.Results:The mean age of patients with GD and without GD was 50.81 ± 16.20 and 50.40 ± 12.43, respectively. Patients with GD were more likely to have diabetes mellitus, a higher body mass index (BMI) (P < 0.001), and higher cholesterol (P < 0.01), and low-density lipoprotein-cholesterol (P < 0.02) levels. No significant differences were found between the groups regarding other atherosclerotic risk factors. Patients with GD had significantly higher rates of the vascular risk factors as intima-media thickness, plaque formation, calcification, aneurysm, mural thrombosis, stenosis, and inflammation in all abdominal arterial segments other than aneurysm in the femoral arteries. In addition, patients with GD had severe atheromatous plaques in the abdominal aorta, common iliac, external iliac, and common femoral artery (CFA). In patients with GD, parameters of age, BMI, and systolic and diastolic blood pressure were all correlated with the severity of the atheromatous plaque in abdominal aorta, common iliac, external iliac, and CFA.Conclusion:We demonstrated a direct relationship between GD and abdominopelvic atheromatous plaque, which is a marker for increased cardiovascular risk, for the first time in the literature. Patients with GD exhibit greater abdominopelvic atherosclerosis and therefore, have a higher risk of cardiovascular disease.

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The Prevalence and Risk Factors of Gallstone Among Adults in South-East of Iran: A Population-Based Study

Cited by 28 publications

References 23 publications

To Study the Level of High-Sensitive C-Reactive Protein With Ultrasonographic Findings as a Predictive Factor for Difficult Laparoscopic Cholecystectomy

To Study the Level of High-Sensitive C-Reactive Protein With Ultrasonographic Findings as a Predictive Factor for Difficult Laparoscopic Cholecystectomy

Acute biliary pancreatitis during pregnancy and post delivery period

The association between gallstone disease and plaque in the abdominopelvic arteries

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