The Prevalence And Intensity Of Malaria Parasite In Children At Jos University Teaching Hospital, Nigeria

Ikeh, EI; Peletiri, IC; Ia, Angyo

doi:10.4314/hmrj.v1i1.33790

Cited by 5 publications

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“…The prevalence of malaria parasitaemia of 27.7% in this study suggests that malaria remains a major cause of morbidity among the under-five aged group in Maiduguri and environs despite several control measures. The observed prevalence is similar to 26%reported by Ben-Edet et al 6 from Lagos and 27-29.5% by Ikeh et al 8 from Jos, Nigeria. However, other studies have found higher prevalences.…”

Section: Discussionsupporting

confidence: 89%

“…However, other studies have found higher prevalences. While this study and the two others 6,8 with similar estimates were tertiary hospital based, the other studies with relatively higher figures were conducted in PHC facilities 7 , secondary facilities 4 or community 5 based studies. This is not surprising as the lower cadre health facilities are the first point of contact, while the tertiary facilities being referral centers may be seeing patients who might have had previous treatment including antimalarials…”

Section: Discussionsupporting

confidence: 49%

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Prevalence and Pattern of Malaria Parasitaemia among Under-Five Febrile Children Attending Paediatric Out-Patient Clinic at University of Maiduguri Teaching Hospital, Maiduguri

Elechi¹,

Rabasa²,

Muhammad³

et al. 2015

Nig. J. Paed.

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Background: Malaria has remained a major public health problem in Nigeria with the under-five aged children and pregnant women being the most affected. The local epidemiological profile of the disease is dynamic owing to the continuous variation in the various determinants and hence the need for periodic re-evaluation. We aim to determine the prevalence of malariaparasitaemia among the under-five aged children and the effect of various determinants. Material and Method: In this cross-sectional study, 433 outpatients aged below 5 years with fever or history of fever in the previous 72hours were enrolled. Relevant information was obtained and recorded using a questionnaire. Thick and thin films were prepared from a finger or heel prick for each of the patients and subjected to microscopy. Result: The prevalence of malaria parasitaemia was 27.7%. Age, sex, nutritional status, socioeconomic class, temperature at presentation as well as ownership of insecticide treated nets had no significant effect on the prevalence of malaria (p>0.05). Only

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Section: Discussionsupporting

confidence: 89%

Section: Discussionsupporting

confidence: 49%

Prevalence and Pattern of Malaria Parasitaemia among Under-Five Febrile Children Attending Paediatric Out-Patient Clinic at University of Maiduguri Teaching Hospital, Maiduguri

Elechi¹,

Rabasa²,

Muhammad³

et al. 2015

Nig. J. Paed.

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“…The overall prevalence of 54.3% obtained in this study shows that malaria still remains an important public health problem despite several control measures and intervention programmes being put in place by the federal government and other NGOs. The prevalence observed in this study is higher than 27.7, 29.5 and 37.65% reported by Ikeh et al (2008) in Plateau State; Elechi et al (2015) in Borno State and Millicent and Gabriel (2015) in Kaduna State respectively but consistent with the findings of Okoli and Solomon (2014), James et al (2013) and NMSI (2010) in Plateau state.…”

Section: Discussionsupporting

confidence: 89%

Prevalence of malaria infection among persons seeking treatment from private drug retailers in North Central Nigeria

Udeh¹,

Hassan²,

Omalu³

et al. 2019

J. Public Health Dis.

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Malaria is a fatal insect-borne tropical disease that continues to pose public health challenges in Nigeria. This study was carried out to assess the prevalence of malaria infection among persons seeking treatment from private sector drug outlets and Proprietary and Patent Medicine Vendors (PVMs). Rapid diagnostic tests and microscopy were carried out to examine the blood samples collected from the study subjects. A total of 1,300 subjects of varying ages that came to seek for malaria treatment were randomly selected for the study after their free consent had been obtained. Finger prick and venous methods were used to collect blood for the rapid diagnostic test and microscopy. The results of this study revealed that of the total of 700 blood samples analyzed for Males, 402 (57.43%) were positive for microscopy and 396 (56.57%) were positive for RDT. While for females, the result showed that of the 600 blood samples screened, 304 (50.67%) were positive for microscopy and 288 (48.0%) were positive for RDT. In respect to age, for microscopy, the age group 15 to 24 years had the highest prevalence of 155 (86.11%) followed by 25 to 34 years with 150 (51.72%), while the least prevalence of 122 (42.36%) occurred within the 55 to 64 age group. For RDT, the age group 15 to 24 years had the highest prevalence of 161 (84.74%) followed by 25 to 34 years with 153 (54.64%), while least prevalence of 108 (38.30%) occurred within the 55 to 64 age group. Statistical analysis indicated that there is a significant difference in infection rate among the age group at p<0.05. The findings of this study further portray the need for confirmatory tests of suspected malaria cases before treatment.

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“…This rate is however higher than 26% reported by Ben-Edet et al [17] from Lagos and 27-29.5% by Ikeh et al [8] from Jos, Nigeria but comparable with other studies with higher preponderances. While this study and the two others [17,18] with lower estimates were tertiary hospital based, the other studies with relatively higher figures were conducted in PHC facilities [19,20], secondary facilities [21] or community [22] based studies. It is therefore noted that the lower level health facilities are usually the first point of contact compared to the tertiary facilities being referral centers could be attending to patients who might have had previous treatment in addition to antimalarial therapies.…”

Section: Resultsmentioning

confidence: 74%

Molecular Surveillance and Burden of Plasmodium falciparum Isolate to the Resistance of Artemisinin and Mefloquine-based Therapy among Febrile Subjects in Ilorin Metropolis, North-Central Nigeria

Nassar

Bakarey

Abubakar

et al. 2021

JAMB

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Introduction: Artemisinin-based combination treatments (ACTs) such as Artemisinin and mefloquine are generally accepted as the best forms of therapy for uncomplicated falciparum malaria and usually exceed more than 90% effectiveness. However, the problem of resistance to the target parasites remains a great challenge especially within the northcentral Nigeria. Therefore this study aimed to assess the burden of resistance of Plasmodium falciparum to artemisinin and Mefloquine from the blood smear febrile patients attending tertiary health facility in Ilorin, Nigeria. Methodology: The study was carried among two hundred and one (201) consented febrile individuals age ranged 1-46 years (Mean=22.7 years; M=39; F=61) between May and August 2019. Blood samples collected were subjected to Microscopy using Giemsa staining technique and Rapid diagnostic test (RDT) using (SD BIOLINE Malaria Ag P.f/Pv, South Korea) kit to detect the presence of P. falciparum A semi-structured questionnaire was used to capture demographic and other relevant information while data was analysed with SPSS version 21. Results: Of the 201 samples tested, 113 (56.5%) were positive for Microscopy and RDT. Fifty of the positive samples for Microscopy and RDT were further subjected to PCR technique for the presence of Plasmodium falciparum and amplification of Kelch13 and FR1gene mutation of which one (2.0%) showed amplification for the PfKelch13 gene mutation for artemisinin while none was recorded for FR1 gene mutation in case of Mefloquine. Conclusion: This study reported a high rate of detection for Plasmodium falciparum using microscopy and RDT but moderately low rate of resistance to amplification for the PfKelch13 gene mutation for artemisinin but none for FR1 gene mutation for mefloquine by PCR. This suggests a clue for further monitoring of the artemisinin and Mefloquine resistance by detection of some molecular markers in k13 and FRI genes of Plasmodium in our communities in Nigeria.

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The Prevalence And Intensity Of Malaria Parasite In Children At Jos University Teaching Hospital, Nigeria

Cited by 5 publications

References 0 publications

Prevalence and Pattern of Malaria Parasitaemia among Under-Five Febrile Children Attending Paediatric Out-Patient Clinic at University of Maiduguri Teaching Hospital, Maiduguri

Prevalence and Pattern of Malaria Parasitaemia among Under-Five Febrile Children Attending Paediatric Out-Patient Clinic at University of Maiduguri Teaching Hospital, Maiduguri

Prevalence of malaria infection among persons seeking treatment from private drug retailers in North Central Nigeria

Molecular Surveillance and Burden of Plasmodium falciparum Isolate to the Resistance of Artemisinin and Mefloquine-based Therapy among Febrile Subjects in Ilorin Metropolis, North-Central Nigeria

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