The Prevalence and Correlation of Non-motor Symptoms in Adult Patients with Idiopathic Focal or Segmental Dystonia

Comprehensive analysis of non-motor symptoms and their association with quality of life in Writer's cramp

“…Psychiatric (anxiety and depression) symptoms and sleep disturbance were the most common traits in our cohort. A recent study reported that patients with WC presented with more symptoms of depression, anxiety, apathy, pain, and impaired sleep quality than did the control subjects, which supported our results [6]. Although our patients suffered relatively high prevalence of anxiety and depression symptoms, the majority of these patients presented mild anxiety and depression symptoms.…”

Anxiety-depressive spectrum disorders in cervical dystonia

“…Результаты нашего исследования подтверждают данные целого ряда работ, которые были выполнены ранее и показали высокую распространенность психопатологии у пациентов с ЦД. Согласно существующим исследованиям, проводимым с помощью психометрических методик, очевидно, что у больных с дистонией выявляются такие симптомы, как апатия, ангедония, нарушения сна, чувство немотивированного беспокойства и снижение социального функционирования [9,[17][18][19][20][21][22][23]. Все эти симптомы потенциально могут приводить к значимому снижению КЖ [24][25][26][27].…”

Clinical and genotypic analysis in determining dystonia non-motor phenotypic heterogeneity: a UK Biobank study

“…Dystonia is increasingly recognised to include both motor and non-motor symptoms, with much of the non-motor work to date focusing on psychiatric symptomatology. Anxiety and depression have been shown to be the most prominent features [ 3 – 6 ], impacting quality of life and motor symptom severity [ 7 ]. Other non-motor features described previously include pain, sleep disturbance and changes to cognitive function, with these being less well investigated, although pain has been reported in up to 88.9% of those with cervical dystonia, with a frequency up to five times higher than unaffected controls [ 6 , 8 ].…”

“…Anxiety and depression have been shown to be the most prominent features [ 3 – 6 ], impacting quality of life and motor symptom severity [ 7 ]. Other non-motor features described previously include pain, sleep disturbance and changes to cognitive function, with these being less well investigated, although pain has been reported in up to 88.9% of those with cervical dystonia, with a frequency up to five times higher than unaffected controls [ 6 , 8 ]. Impaired sleep quality has also been reported in up to 77.3% of those with cervical dystonia, together with increased rates of excessive daytime sleepiness and fatigue.…”

“…Impaired sleep quality has also been reported in up to 77.3% of those with cervical dystonia, together with increased rates of excessive daytime sleepiness and fatigue. [ 5 , 6 , 9 – 11 ]. Sleep disturbance has been linked to higher levels of anxiety, depression and pain, suggesting interplay between these multiple non-motor traits [ 11 , 12 ].…”