The presence of luteinized unruptured follicle syndrome and altered folliculogenesis in rats with surgically induced endometriosis

Moon, Carol Eve M.; Bertero, Maria C.; Curry, Thomas E.; London, Steven N.; Muse, Ken N.; Sharpe, Kathy L.; Vernon, Michael

doi:10.1016/0002-9378(93)90642-v

Cited by 33 publications

(34 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In vivo TIMP1-modulating treatments confirmed earlier reports in this model: Endo rats had fewer follicles and CLs, increased LUFs, and poorer embryo quality compared to Sham rats [15,17]. Adding endometriotic levels of TIMP1 to the peritoneal cavity of Sham rats resulted in a recapitulation of the aberrant in vivo phenomena, providing more evidence that …”

Section: Discussionsupporting

confidence: 83%

“…Differences in the numbers of follicles and CLs between treatment groups were evaluated histologically and quantified morphometrically as described previously [15,17]. These morphometric calculations were based on size so that no antral follicle, CL, or luteinized unruptured follicle (LUF) was counted more than once in each ovary [15].…”

Section: Determination Of the Effect Of In Vivo Modulation Of Timp1 Imentioning

confidence: 99%

“…These morphometric calculations were based on size so that no antral follicle, CL, or luteinized unruptured follicle (LUF) was counted more than once in each ovary [15]. All the morphological and morphometric analyses were performed by two investigators blinded to the study group.…”

Section: Determination Of the Effect Of In Vivo Modulation Of Timp1 Imentioning

confidence: 99%

“…Rats with surgically induced endometriosis (Endo) display pathophysiologies similar to those of primates and humans with the disease, including pain and infertility [12][13][14]. An association between the presence of ectopic endometriotic implants and reduced fecundity in rats has been described [13,[15][16][17].…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Proteasomes and Proteasome Activator 200 kDa (PA200) Accumulate on Chromatin in Response to Ionizing Radiation

Blickwedehl¹,

McEvoy²,

Wong³

et al. 2007

Radiation Research

View full text Add to dashboard Cite

Section: Discussionsupporting

confidence: 83%

Section: Determination Of the Effect Of In Vivo Modulation Of Timp1 Imentioning

confidence: 99%

Section: Determination Of the Effect Of In Vivo Modulation Of Timp1 Imentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Proteasomes and Proteasome Activator 200 kDa (PA200) Accumulate on Chromatin in Response to Ionizing Radiation

Blickwedehl¹,

McEvoy²,

Wong³

et al. 2007

Radiation Research

View full text Add to dashboard Cite

“…The presence of luteinized follicles has been observed in ageing rats, structures that are abnormal in young rats (Acuna et al 2009). Luteinized follicles are characterised by the presence of luteinized granulosa cells (they contain a big cytoplasm similar to luteal cells), and an antral cavity (although there is no oocyte) (Smirnova 1964, Moon et al 1993). These alternative structures, which appear in the ovary of rats during the subfertile period, may produce hormones and paracrine factors, which potentially affect the development of other follicles.…”

Section: R62mentioning

confidence: 99%

Ovarian function and reproductive senescence in the rat: role of ovarian sympathetic innervation

2017

View full text Add to dashboard Cite

Successful reproduction is the result of a myriad interactions in which the ovary and the ovarian follicular reserve play a fundamental role. At present, women who delay maternity until after 30 years of age have a decreased fertility rate due to various causes, including damaged follicles and a reduction in the reserve pool of follicles. Therefore, the period just prior to menopause, also known as the subfertile period, is important. The possibility of modulating the follicular pool and the health of follicles during this period to improve fertility is worth exploring. We have developed an animal model to study the ovarian ageing process during this subfertile period to understand the mechanisms responsible for reproductive senescence. In the rat model, we have shown that the sympathetic nervous system participates in regulating the follicular development during ovarian ageing. This article reviews the existing evidence on the presence and functional role of sympathetic nerve activity in regulating the follicular development during ovarian ageing, with a focus on the subfertile period. Free Spanish abstract: A Spanish translation of this abstract is freely available at http://www.reproduction-online.org/content/153/2/ R59/suppl/DC1. Reproduction (2017) 153 R59-R68

show abstract

Identifying Mechanisms of Endometriosis-Associated Reduced Fecundity in a Rat Model: Novel Insights toward Understanding Human Infertility

Sharpe-Timms

Nabli

Stilley

2020

Advances in Anatomy, Embryology and Cell Biology

View full text Add to dashboard Cite

The presence of luteinized unruptured follicle syndrome and altered folliculogenesis in rats with surgically induced endometriosis

Cited by 33 publications

References 16 publications

Proteasomes and Proteasome Activator 200 kDa (PA200) Accumulate on Chromatin in Response to Ionizing Radiation

Proteasomes and Proteasome Activator 200 kDa (PA200) Accumulate on Chromatin in Response to Ionizing Radiation

Ovarian function and reproductive senescence in the rat: role of ovarian sympathetic innervation

Identifying Mechanisms of Endometriosis-Associated Reduced Fecundity in a Rat Model: Novel Insights toward Understanding Human Infertility

Contact Info

Product

Resources

About